{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T14:49:37Z","timestamp":1775918977203,"version":"3.50.1"},"reference-count":55,"publisher":"IOP Publishing","issue":"10","license":[{"start":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T00:00:00Z","timestamp":1526515200000},"content-version":"vor","delay-in-days":16,"URL":"https:\/\/publishingsupport.iopscience.iop.org\/iop-standard\/v1"},{"start":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T00:00:00Z","timestamp":1526515200000},"content-version":"tdm","delay-in-days":16,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Phys. Med. Biol."],"published-print":{"date-parts":[[2018,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>With recent changes in the recommended annual limit on eye lens exposures to ionizing radiation, there is considerable interest in predictive computational dosimetry models of the human eye and its various ocular structures including the crystalline lens, ciliary body, cornea, retina, optic nerve, and central retinal artery. Computational eye models to date have been constructed as stylized models, high-resolution voxel models, and polygon mesh models. Their common feature, however, is that they are typically constructed of nominal size and of a roughly spherical shape associated with the emmetropic eye. In this study, we present a geometric eye model that is both scalable (allowing for changes in eye size) and deformable (allowing for changes in eye shape), and that is suitable for use in radiation transport studies of ocular exposures and radiation treatments of eye disease. The model allows continuous and variable changes in eye size (axial lengths from 20 to 26\u2009mm) and eye shape (diopters from\u2009\u2009\u221212 to\u2009\u2009+6). As an explanatory example of its use, five models (emmetropic eyes of small, average, and large size, as well as average size eyes of\u2009\u2009\u221212D and\u2009\u2009+6D) were constructed and subjected to normally incident beams of monoenergetic electrons and photons, with resultant energy-dependent dose coefficients presented for both anterior and posterior eye structures. Electron dose coefficients were found to vary with changes to both eye size and shape for the posterior eye structures, while their values for the crystalline lens were found to be sensitive to changes in only eye size. No dependence upon eye size or eye shape was found for photon dose coefficients at energies below 2 MeV. Future applications of the model can include more extensive tabulations of dose coefficients to all ocular structures (not only the lens) as a function of eye size and shape, as well as the assessment of x-ray therapies for ocular disease for patients with non-emmetropic eyes.<\/jats:p>","DOI":"10.1088\/1361-6560\/aab955","type":"journal-article","created":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T16:18:09Z","timestamp":1521821889000},"page":"105017","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":13,"title":["A scalable and deformable stylized model of the adult human eye for radiation dose assessment"],"prefix":"10.1088","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3416-2924","authenticated-orcid":false,"given":"Daniel","family":"El Basha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2124-5472","authenticated-orcid":false,"given":"Takuya","family":"Furuta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3442-2311","authenticated-orcid":false,"given":"Siva S R","family":"Iyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7175-9968","authenticated-orcid":false,"given":"Wesley E","family":"Bolch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"266","published-online":{"date-parts":[[2018,5,17]]},"reference":[{"key":"pmbaab955bib001","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1667\/RR1688.1","type":"journal-article","article-title":"Radiation cataractogenesis: a review of recent studies","volume":"172","author":"Ainsbury","year":"2009","journal-title":"Radiat. Res."},{"key":"pmbaab955bib002","doi-asserted-by":"publisher","first-page":"8846","DOI":"10.14260\/jemds\/2015\/1282","type":"journal-article","article-title":"Relation of refractive error with corneal curvature of the eye in subjects with refractive error","volume":"4","author":"Arora","year":"2015","journal-title":"J. Evol. Med. Dent. Sci."},{"key":"pmbaab955bib003","doi-asserted-by":"publisher","first-page":"3380","DOI":"10.1167\/iovs.04-0292","type":"journal-article","article-title":"Eye shape in emmetropia and myopia","volume":"45","author":"Atchison","year":"2004","journal-title":"Investigative Ophthalmol. Vis. Sci."},{"key":"pmbaab955bib004","doi-asserted-by":"publisher","first-page":"2698","DOI":"10.1167\/iovs.04-1506","type":"journal-article","article-title":"Shape of the retinal surface in emmetropia and myopia","volume":"46","author":"Atchison","year":"2005","journal-title":"Investigative Ophthalmol. Vis. Sci."},{"key":"pmbaab955bib005","doi-asserted-by":"publisher","first-page":"4353","DOI":"10.1167\/iovs.08-2008","type":"journal-article","article-title":"Ciliary body thickness and refractive error in children","volume":"49","author":"Bailey","year":"2008","journal-title":"Investigative Ophthalmol. Vis. Sci."},{"key":"pmbaab955bib006","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1093\/rpd\/ncw194","type":"journal-article","article-title":"Compilation of conversion coefficients for the dose to the lens of the eye","volume":"174","author":"Behrens","year":"2017","journal-title":"Radiat. Prot. Dosim."},{"key":"pmbaab955bib007","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1088\/0031-9155\/56\/2\/009","type":"journal-article","article-title":"Dose conversion coefficients for photon exposure of the human eye lens","volume":"56","author":"Behrens","year":"2011","journal-title":"Phys. Med. Biol."},{"key":"pmbaab955bib008","doi-asserted-by":"publisher","first-page":"4069","DOI":"10.1088\/0031-9155\/54\/13\/008","type":"journal-article","article-title":"Dose conversion coefficients for electron exposure of the human eye lens","volume":"54","author":"Behrens","year":"2009","journal-title":"Phys. Med. Biol."},{"key":"pmbaab955bib009","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1177\/0146645314562320","type":"journal-article","article-title":"Dosimetric models of the eye and lens of the eye and their use in assessing dose coefficients for ocular exposures","volume":"44","author":"Bolch","year":"2015","journal-title":"Ann. ICRP"},{"key":"pmbaab955bib010","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1136\/bjo.2006.099879","type":"journal-article","article-title":"Linear relationship of refractive and biometric lenticular changes during accommodation in emmetropic and myopic eyes","volume":"91","author":"Bolz","year":"2007","journal-title":"Br. J. Ophthalmol."},{"key":"pmbaab955bib011","doi-asserted-by":"publisher","first-page":"6887","DOI":"10.1088\/0031-9155\/58\/19\/6887","type":"journal-article","article-title":"Influence of eye size and beam entry angle on dose to non-targeted tissues of the eye during stereotactic x-ray radiosurgery of AMD","volume":"58","author":"Cantley","year":"2013","journal-title":"Phys. Med. Biol."},{"key":"pmbaab955bib012","doi-asserted-by":"publisher","first-page":"5261","DOI":"10.1088\/0031-9155\/59\/18\/5261","type":"journal-article","article-title":"Multi-resolution voxel phantom modeling: a high-resolution eye model for computational dosimetry","volume":"59","author":"Caracappa","year":"2014","journal-title":"Phys. Med. Biol."},{"key":"pmbaab955bib013","first-page":"311","type":"journal-article","article-title":"Corneal topography and myopia. A cross-sectional study","volume":"38","author":"Carney","year":"1997","journal-title":"Investigative Ophthalmol. Vis. Sci."},{"key":"pmbaab955bib014","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1088\/0031-9155\/20\/2\/002","type":"journal-article","article-title":"Dimensions of the human eye relevant to radiation protection","volume":"20","author":"Charles","year":"1975","journal-title":"Phys. Med. Biol."},{"key":"pmbaab955bib015","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1097\/OPX.0000000000000298","type":"journal-article","article-title":"Measurement of anterior scleral curvature using anterior segment OCT","volume":"91","author":"Choi","year":"2014","journal-title":"Optom. Vis. Sci."},{"key":"pmbaab955bib016","doi-asserted-by":"publisher","author":"Denniston","year":"2014","DOI":"10.1093\/med\/9780199679980.001.0001","type":"book"},{"key":"pmbaab955bib017","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1111\/j.1755-3768.2011.02235.x","type":"journal-article","article-title":"Allvar Gullstrand (1862\u20131930)\u2014the gentleman with the lamp","volume":"89","author":"Ehinger","year":"2011","journal-title":"Acta Ophthalmol."},{"key":"pmbaab955bib018","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/j.ajo.2012.07.015","type":"journal-article","article-title":"The relationship between axial length and choroidal thickness in eyes with high myopia","volume":"155","author":"Flores-Moreno","year":"2013","journal-title":"Am. J. Ophthalmol."},{"key":"pmbaab955bib019","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/j.ajo.2009.04.029","type":"journal-article","article-title":"Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes","volume":"148","author":"Fujiwara","year":"2009","journal-title":"Am. J. Ophthalmol."},{"key":"pmbaab955bib020","doi-asserted-by":"publisher","first-page":"296","DOI":"10.3928\/15428877-20120426-02","type":"journal-article","article-title":"Enhanced depth imaging optical coherence tomography: choroidal thickness and correlations with age, refractive error, and axial length","volume":"43","author":"Goldenberg","year":"2012","journal-title":"Ophthalmic Surg. Lasers Imaging"},{"key":"pmbaab955bib021","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1097\/OPX.0b013e3181622602","type":"journal-article","article-title":"Axial length, corneal radius, and age of myopia onset","volume":"85","author":"Gonzalez Blanco","year":"2008","journal-title":"Optom. Vis. Sc."},{"key":"pmbaab955bib022","author":"Gross","year":"2008","type":"book"},{"key":"pmbaab955bib023","doi-asserted-by":"publisher","first-page":"2644","DOI":"10.1167\/iovs.09-4774","type":"journal-article","article-title":"Comparison of retinal thickness in normal eyes using stratus and spectralis optical coherence tomography","volume":"51","author":"Grover","year":"2010","journal-title":"Investigative Ophthalmol. Vis. Sci."},{"key":"pmbaab955bib024","doi-asserted-by":"publisher","first-page":"3671","DOI":"10.1118\/1.3168554","type":"journal-article","article-title":"Kilovoltage stereotactic radiosurgery for age-related macular degeneration: assessment of optic nerve dose and patient effective dose","volume":"36","author":"Hanlon","year":"2009","journal-title":"Med. Phys."},{"key":"pmbaab955bib025","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.joco.2017.08.009","type":"journal-article","article-title":"Global and regional estimates of prevalence of refractive errors: systematic review and meta-analysis","volume":"30","author":"Hassan","year":"2018","journal-title":"J. Curr. Ophthal."},{"key":"pmbaab955bib026","author":"Hirayama","year":"2005","type":"report"},{"key":"pmbaab955bib027","first-page":"1","type":"journal-article","article-title":"ICRP Publication 110: adult reference computational phantoms","volume":"39","author":"ICRP","year":"2009","journal-title":"Ann. ICRP"},{"key":"pmbaab955bib028","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.icrp.2011.10.001","type":"journal-article","article-title":"ICRP publication 116: conversion coefficients for radiological protection quantities for external radiation exposures","volume":"40","author":"ICRP","year":"2010","journal-title":"Ann. ICRP"},{"key":"pmbaab955bib029","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.icrp.2012.02.001","type":"journal-article","article-title":"ICRP publication 118: ICRP Statement on tissue reactions and early and late effects of radiation in normal tissues and organs: threshold doses for tissue reactionsin a radiation protection context","volume":"41","author":"ICRP","year":"2012","journal-title":"Ann. ICRP"},{"key":"pmbaab955bib030","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.icrp.2013.05.004","type":"journal-article","article-title":"ICRP publication 123: assessment of radiation exposure of astronauts in space","volume":"42","author":"ICRP","year":"2013","journal-title":"Ann. ICRP"},{"key":"pmbaab955bib031","author":"ICRU","year":"1992","type":"book"},{"key":"pmbaab955bib032","first-page":"1","type":"journal-article","article-title":"ICRU report 84: reference data for the validation of doses from cosmic-radiation exposure of aircraft crew","volume":"10","author":"ICRU","year":"2010","journal-title":"J. ICRU"},{"key":"pmbaab955bib033","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1080\/00223131.2017.1297742","type":"journal-article","article-title":"Benchmark study of the recent version of the PHITS code","volume":"54","author":"Iwamoto","year":"2017","journal-title":"J. Nucl. Sci. Technol."},{"key":"pmbaab955bib034","doi-asserted-by":"publisher","first-page":"1791","DOI":"10.1167\/iovs.15-18529","type":"journal-article","article-title":"Retinal thickness and axial length","volume":"57","author":"Jonas","year":"2016","journal-title":"Investigative Ophthalmol. Vis. Sci."},{"key":"pmbaab955bib035","doi-asserted-by":"publisher","first-page":"5151","DOI":"10.1118\/1.2990780","type":"journal-article","article-title":"Dosimetry characterization of a multibeam radiotherapy treatment for age-related macular degeneration","volume":"35","author":"Lee","year":"2008","journal-title":"Med. Phys."},{"key":"pmbaab955bib036","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1097\/IJG.0b013e318264ba68","type":"journal-article","article-title":"Differences in iris thickness among african americans, caucasian americans, hispanic americans, chinese americans, and filipino-americans","volume":"22","author":"Lee","year":"2013","journal-title":"J. Glaucoma"},{"key":"pmbaab955bib037","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.meddos.2015.10.005","type":"journal-article","article-title":"Ion therapy for uveal melanoma in new human eye phantom based on GEANT4 toolkit","volume":"41","author":"Mahdipour","year":"2016","journal-title":"Med. Dosim."},{"key":"pmbaab955bib038","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.exer.2013.01.014","type":"journal-article","article-title":"Regulation of scleral metabolism in myopia and the role of transforming growth factor-beta","volume":"114","author":"McBrien","year":"2013","journal-title":"Exp. Eye Res."},{"key":"pmbaab955bib039","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/S1350-9462(02)00063-0","type":"journal-article","article-title":"Role of the sclera in the development and pathological complications of myopia","volume":"22","author":"McBrien","year":"2003","journal-title":"Prog. Retinal Eye Res."},{"key":"pmbaab955bib040","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1038\/eye.2008.178","type":"journal-article","article-title":"Ciliary body thickness in unilateral high axial myopia","volume":"23","author":"Muftuoglu","year":"2009","journal-title":"Eye"},{"key":"pmbaab955bib041","author":"NCRP","year":"1999","type":"book"},{"key":"pmbaab955bib042","doi-asserted-by":"publisher","first-page":"8695","DOI":"10.1088\/0031-9155\/60\/22\/8695","type":"journal-article","article-title":"Incorporation of detailed eye model into polygon-mesh versions of ICRP-110 reference phantoms","volume":"60","author":"Nguyen","year":"2015","journal-title":"Phys. Med. Biol."},{"key":"pmbaab955bib043","doi-asserted-by":"publisher","first-page":"6919","DOI":"10.1088\/0031-9155\/56\/21\/010","type":"journal-article","article-title":"Dose conversion coefficients for monoenergetic electrons incident on a realistic human eye model with different lens cell populations","volume":"56","author":"Nogueira","year":"2011","journal-title":"Phys. Med. Biol."},{"key":"pmbaab955bib044","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1111\/j.1600-0420.2005.00498.x","type":"journal-article","article-title":"Central corneal thickness in high myopia","volume":"83","author":"Pedersen","year":"2005","journal-title":"Acta Ophthalmol. Scand."},{"key":"pmbaab955bib045","doi-asserted-by":"publisher","first-page":"5039","DOI":"10.1364\/BOE.6.005039","type":"journal-article","article-title":"OCT-based crystalline lens topography in accommodating eyes","volume":"6","author":"Perez-Merino","year":"2015","journal-title":"Biomed. Opt. Express"},{"key":"pmbaab955bib046","doi-asserted-by":"publisher","first-page":"135","DOI":"10.3928\/15428877-20120102-03","type":"journal-article","article-title":"Anterior segment dimensions in asian and caucasian eyes measured by optical coherence tomography","volume":"43","author":"Qin","year":"2012","journal-title":"Ophthalmic Surg. Lasers Imaging"},{"key":"pmbaab955bib047","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/j.ajo.2010.05.009","type":"journal-article","article-title":"Long-term changes in axial length in adult eyes with pathologic myopia","volume":"150","author":"Saka","year":"2010","journal-title":"Am. J. Ophthalmol."},{"key":"pmbaab955bib048","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1080\/00223131.2017.1419890","type":"journal-article","article-title":"Features of particle and heavy ion transport code system (PHITS) version 3.02","volume":"55","author":"Sato","year":"2018","journal-title":"J. Nucl. Sci. Technol."},{"key":"pmbaab955bib049","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1097\/OPX.0b013e3181a7b3ce","type":"journal-article","article-title":"Accommodative fluctuations, lens tension, and ciliary body thickness in children","volume":"86","author":"Schultz","year":"2009","journal-title":"Optom. Vis. Sci."},{"key":"pmbaab955bib050","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1111\/aos.13184","type":"journal-article","article-title":"Curvature of iris profile in spectral domain optical coherence tomography and dependency to refraction, age and pupil size\u2014the MIPH eye&health study","volume":"95","author":"Schuster","year":"2017","journal-title":"Acta Ophthalmol."},{"key":"pmbaab955bib051","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/j.jacr.2009.12.015","type":"journal-article","article-title":"Radiation exposure from medical imaging in patients with chronic and recurrent conditions","volume":"7","author":"Stein","year":"2010","journal-title":"J. Am. Coll. Radiol."},{"key":"pmbaab955bib052","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1080\/02713689808951218","type":"journal-article","article-title":"Hyperopia is predominantly axial in nature","volume":"17","author":"Strang","year":"1998","journal-title":"Curr. Eye Res."},{"key":"pmbaab955bib053","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1667\/RR2207.1","type":"journal-article","article-title":"Radiation cataract risk in interventional cardiology personnel","volume":"174","author":"Vano","year":"2010","journal-title":"Radiat. Res."},{"key":"pmbaab955bib054","author":"Worgul","year":"1991","type":"book"},{"key":"pmbaab955bib055","author":"Wyszecki","year":"1982","edition":"2nd edn","type":"book"}],"container-title":["Physics in Medicine &amp; Biology"],"original-title":[],"link":[{"URL":"http:\/\/stacks.iop.org\/0031-9155\/63\/i=10\/a=105017?key=crossref.044cdd86b14d954be2760fbf2472c4a9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aab955\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"http:\/\/stacks.iop.org\/0031-9155\/63\/i=10\/a=105017\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aab955","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aab955","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aab955\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aab955\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aab955\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aab955\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"},{"URL":"http:\/\/stacks.iop.org\/0031-9155\/63\/i=10\/a=105017\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/stacks.iop.org\/0031-9155\/63\/i=10\/a=105017?key=crossref.044cdd86b14d954be2760fbf2472c4a9","content-type":"text\/html","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aab955\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T13:56:17Z","timestamp":1775915777000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aab955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,1]]},"references-count":55,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2018,5,17]]},"published-print":{"date-parts":[[2018,5,1]]}},"URL":"https:\/\/doi.org\/10.1088\/1361-6560\/aab955","relation":{},"ISSN":["0031-9155","1361-6560"],"issn-type":[{"value":"0031-9155","type":"print"},{"value":"1361-6560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,1]]},"assertion":[{"value":"A scalable and deformable stylized model of the adult human eye for radiation dose assessment","name":"article_title","label":"Article Title"},{"value":"Physics in Medicine & Biology","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2018 Institute of Physics and Engineering in Medicine. All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2017-09-10","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2018-03-23","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2018-05-17","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}