{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T14:41:01Z","timestamp":1788273661938,"version":"build-2803163510"},"reference-count":48,"publisher":"IOP Publishing","issue":"1","license":[{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"name":"Beijing Natural Science Foundation of China","award":["7254433"],"award-info":[{"award-number":["7254433"]}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Phys. Med. Biol."],"published-print":{"date-parts":[[2026,1,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Objective.<\/jats:italic>\n                    This study aimed to automate the extraction of local corneal topography (CT) features in myopic children undergoing orthokeratology (OK), evaluate their causal effects on axial length (AL) control, and develop a predictive model for AL progression.\n                    <jats:italic>Approach.<\/jats:italic>\n                    We retrospectively analyzed myopic children who had received OK treatment for more than 12 months. Advanced digital image processing techniques were employed to automatically quantify three critical CT parameters: treatment zone area (TZA), eccentric distance (ED), and eccentric angle (EA). Counterfactual inference quantified causal relationships between these parameters and AL changes. Baseline characteristics and one-month CT features were used to train a CatBoost prediction model.\n                    <jats:italic>Main results.<\/jats:italic>\n                    This study included 143 myopic subjects (276 eyes) treated with OK lenses. The image processing algorithm performed comparably to manual annotation, with mean absolute percentage errors of 2.1% (TZA), 1.2% (ED), and 0.7% (EA). Per unit increase, TZA, ED, and EA were associated with AL changes of 0.054 mm, \u22120.161 mm, and \u22120.0003 mm, respectively. The CatBoost model, using initial AL and age, predicted six-month and one-year AL with absolute errors of 0.180 and 0.169 mm.\n                    <jats:italic>Significance.<\/jats:italic>\n                    This work establishes an integrated artificial intelligence (AI) framework that combines automated CT analysis, causal inference, and predictive modeling. It provides clinicians with an interpretable tool for assessing OK efficacy and forecasting myopia progression, while paving the way for next-generation healthcare AI systems with integrated perceptual, explanatory, and prognostic capabilities.\n                  <\/jats:p>","DOI":"10.1088\/1361-6560\/ae2b47","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T22:56:34Z","timestamp":1765407394000},"page":"015018","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Artificial intelligence for predicting the axial length response of orthokeratology in myopic children"],"prefix":"10.1088","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4664-4031","authenticated-orcid":true,"given":"Xin","family":"Rong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1374-935X","authenticated-orcid":false,"given":"Zihui","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6964-1685","authenticated-orcid":false,"given":"Zihang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5939-3932","authenticated-orcid":true,"given":"Tianhao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6504-0087","authenticated-orcid":true,"given":"Guangming","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4450-8642","authenticated-orcid":false,"given":"Liu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2025,12,30]]},"reference":[{"key":"pmbae2b47bib1","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1136\/bjophthalmol-2019-315575","type":"journal-article","article-title":"Review: myopia control strategies recommendations from the 2018 WHO\/IAPB\/BHVI meeting on Myopia","volume":"104","author":"Ang","year":"2020","journal-title":"Br. J. Ophthalmol."},{"key":"pmbae2b47bib2","doi-asserted-by":"publisher","first-page":"7567","DOI":"10.3390\/jcm13247567","type":"journal-article","article-title":"Orthokeratology lens decentration with two designs of corneal refractive therapy\u2122 lenses: a one-year prospective study","volume":"13","author":"Batres","year":"2024","journal-title":"J. Clin. Med."},{"key":"pmbae2b47bib3","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/j.clae.2020.03.018","type":"journal-article","article-title":"Overnight orthokeratology","volume":"43","author":"Bullimore","year":"2020","journal-title":"Contact Lens Anterior Eye"},{"key":"pmbae2b47bib4","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1097\/ICL.0000000000001054","type":"journal-article","article-title":"Deep learning based prediction of myopia control effect in children treated with overnight orthokeratology","volume":"50","author":"Cao","year":"2024","journal-title":"Eye Contact Lens."},{"key":"pmbae2b47bib5","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1111\/opo.12812","type":"journal-article","article-title":"Axial length targets for myopia control","volume":"41","author":"Chamberlain","year":"2021","journal-title":"Ophthalmic Physiol. Opt."},{"key":"pmbae2b47bib6","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2025.102446","type":"journal-article","article-title":"Changes of axial elongation and corneal topography after switching from standard to reduced back optic zone diameter orthokeratology lenses","volume":"48","author":"Chen","year":"2025","journal-title":"Contact Lens Anterior Eye"},{"key":"pmbae2b47bib7","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1136\/bjophthalmol-2020-317980","type":"journal-article","article-title":"Two-year add-on effect of using low concentration atropine in poor responders of orthokeratology in myopic children","volume":"106","author":"Chen","year":"2022","journal-title":"Br. J. Ophthalmol."},{"key":"pmbae2b47bib8","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2023.108095","type":"journal-article","article-title":"Trends in digital image processing of isolated microalgae by incorporating classification algorithm","volume":"63","author":"Chong","year":"2023","journal-title":"Biotechnol. Adv."},{"key":"pmbae2b47bib9","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1097\/ICL.0000000000000981","type":"journal-article","article-title":"Is orthokeratology treatment zone decentration effective and safe in controlling myopic progression?","volume":"49","author":"Chu","year":"2023","journal-title":"Eye Contact Lens."},{"key":"pmbae2b47bib10","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1097\/ICL.0000000000000985","type":"journal-article","article-title":"Effects of orthokeratology lens decentration induced by paracentral corneal asymmetry on axial length elongation","volume":"49","author":"Ding","year":"2023","journal-title":"Eye Contact Lens."},{"key":"pmbae2b47bib11","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.1057863","type":"journal-article","article-title":"Machine learning for predicting the treatment effect of orthokeratology in children","volume":"10","author":"Fang","year":"2022","journal-title":"Front. Pediatr."},{"key":"pmbae2b47bib12","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.clae.2019.11.006","type":"journal-article","article-title":"Reducing treatment zone diameter in orthokeratology and its effect on peripheral ocular refraction","volume":"43","author":"Gifford","year":"2020","journal-title":"Contact Lens Anterior Eye"},{"key":"pmbae2b47bib13","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2024.102316","type":"journal-article","article-title":"Impact of back optic zone diameter (BOZD) in orthokeratology on axial length elongation: a meta-analysis and systematic review","volume":"48","author":"Gu","year":"2025","journal-title":"Contact Lens Anterior Eye"},{"key":"pmbae2b47bib14","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1111\/opo.12834","type":"journal-article","article-title":"One-year results of the variation of orthokeratology lens treatment zone (VOLTZ) study: a prospective randomised clinical trial","volume":"41","author":"Guo","year":"2021","journal-title":"Ophthalmic Physiol. Opt."},{"key":"pmbae2b47bib15","doi-asserted-by":"publisher","first-page":"417","DOI":"10.3414\/ME13-10-0123","type":"journal-article","article-title":"Boosting\u2014an unusual yet attractive optimiser","volume":"53","author":"Hothorn","year":"2014","journal-title":"Methods Inf. Med."},{"key":"pmbae2b47bib16","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1136\/bjophthalmol-2018-312933","type":"journal-article","article-title":"Areal summed corneal power shift is an important determinant for axial length elongation in myopic children treated with overnight orthokeratology","volume":"103","author":"Hu","year":"2019","journal-title":"Br. J. Ophthalmol."},{"key":"pmbae2b47bib17","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1080\/02713683.2023.2167212","type":"journal-article","article-title":"Development and validation of a simple nomogram for predicting rapid myopia progression in children with orthokeratology management","volume":"48","author":"Huang","year":"2023a","journal-title":"Curr. Eye Res."},{"key":"pmbae2b47bib18","doi-asserted-by":"publisher","first-page":"7715","DOI":"10.1038\/s41598-023-34580-3","type":"journal-article","article-title":"Factors influencing axial elongation in myopic children using overnight orthokeratology","volume":"13","author":"Huang","year":"2023b","journal-title":"Sci. Rep."},{"key":"pmbae2b47bib19","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1111\/aos.14911","type":"journal-article","article-title":"Control of myopia using orthokeratology lenses in Scandinavian children aged 6\u201312 years. Eighteen-month data from the Danish randomized study: clinical study of near-sightedness; TREATMENT with orthokeratology lenses (CONTROL study)","volume":"100","author":"Jakobsen","year":"2022","journal-title":"Acta Ophthalmol."},{"key":"pmbae2b47bib20","doi-asserted-by":"publisher","first-page":"1525","DOI":"10.1111\/opo.13551","type":"journal-article","article-title":"Comparison of two designs of orthokeratology lenses with smaller back optic zone diameters in myopia control","volume":"45","author":"Jing","year":"2025","journal-title":"Ophthalmic Physiol. Opt."},{"key":"pmbae2b47bib21","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1167\/iovs.61.2.22","type":"journal-article","article-title":"Higher-order aberrations and axial elongation in myopic children treated with orthokeratology","volume":"61","author":"Lau","year":"2020","journal-title":"Investigative Ophthalmol. Vis. Sci."},{"key":"pmbae2b47bib22","doi-asserted-by":"publisher","DOI":"10.1088\/3049-4761\/adce0d","type":"journal-article","article-title":"Engineering artificial intelligence: framework, challenges, and future direction","volume":"1","author":"Lee","year":"2025","journal-title":"Mach. Learn."},{"key":"pmbae2b47bib23","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2024.102178","type":"journal-article","article-title":"Influence of back optic zone diameter on corneal morphology with orthokeratology lenses","volume":"48","author":"Li","year":"2025","journal-title":"Contact Lens Anterior Eye"},{"key":"pmbae2b47bib24","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2022.101755","type":"journal-article","article-title":"The effect of back optic zone diameter on relative corneal refractive power distribution and corneal higher-order aberrations in orthokeratology","volume":"46","author":"Li","year":"2023","journal-title":"Contact Lens Anterior Eye"},{"key":"pmbae2b47bib25","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.798314","type":"journal-article","article-title":"Comparison of two main orthokeratology lens designs in efficacy and safety for myopia control","volume":"9","author":"Lu","year":"2022","journal-title":"Front. Med. Lausanne"},{"key":"pmbae2b47bib26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2016\/1732476","type":"journal-article","article-title":"Repeatability and reproducibility of quantitative corneal shape analysis after orthokeratology treatment using image-pro plus software","volume":"2016","author":"Mei","year":"2016","journal-title":"J. Ophthalmol."},{"key":"pmbae2b47bib27","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.infoh.2025.03.001","type":"journal-article","article-title":"Next-generation agentic AI for transforming healthcare","volume":"2","author":"Nalan","year":"2025","journal-title":"Inform. Health"},{"key":"pmbae2b47bib28","doi-asserted-by":"publisher","first-page":"1843","DOI":"10.18240\/ijo.2024.10.10","type":"journal-article","article-title":"Effects of different orthokeratology lens designs on slowing axial length elongation in children with myopia","volume":"17","author":"Ni","year":"2024","journal-title":"Int. J. Ophthalmol."},{"key":"pmbae2b47bib29","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1111\/cxo.12947","type":"journal-article","article-title":"Optical changes and visual performance with orthokeratology","volume":"103","author":"Nti","year":"2020","journal-title":"Clin. Exp. Optom."},{"key":"pmbae2b47bib30","doi-asserted-by":"publisher","first-page":"336","DOI":"10.3390\/jcm10020336","type":"journal-article","article-title":"The role of back optic zone diameter in myopia control with orthokeratology lenses","volume":"10","author":"Paun\u00e9","year":"2021","journal-title":"J. Clin. Med."},{"key":"pmbae2b47bib31","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1109\/TMI.2023.3331488","type":"journal-article","article-title":"Prediction of myopia eye axial elongation with orthokeratology treatment via dense I2I based corneal topography change analysis","volume":"43","author":"Rong","year":"2024","journal-title":"IEEE Trans. Med. Imaging"},{"key":"pmbae2b47bib32","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1186\/s12886-022-02310-4","type":"journal-article","article-title":"The effect of orthokeratology treatment zone decentration on myopia progression","volume":"22","author":"Sun","year":"2022","journal-title":"BMC Ophthalmol."},{"key":"pmbae2b47bib33","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1186\/s40662-020-00214-2","type":"journal-article","article-title":"A machine learning-based algorithm used to estimate the physiological elongation of ocular axial length in myopic children","volume":"7","author":"Tang","year":"2020","journal-title":"Eye Vis."},{"key":"pmbae2b47bib34","doi-asserted-by":"publisher","first-page":"e76","DOI":"10.1111\/aos.16678","type":"journal-article","article-title":"Machine learning-based nomogram to predict poor response to overnight orthokeratology in Chinese myopic children: a multicentre, retrospective study","volume":"103","author":"Tang","year":"2025","journal-title":"Acta Ophthalmol."},{"key":"pmbae2b47bib35","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1167\/tvst.10.14.21","type":"journal-article","article-title":"A deep learning-based framework for accurate evaluation of corneal treatment zone after orthokeratology","volume":"10","author":"Tang","year":"2021","journal-title":"Transl Vis. Sci. Technol."},{"key":"pmbae2b47bib36","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.clae.2021.02.003","type":"journal-article","article-title":"CLEAR\u2014orthokeratology","volume":"44","author":"Vincent","year":"2021","journal-title":"Contact Lens Anterior Eye"},{"key":"pmbae2b47bib37","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1186\/s12886-024-03398-6","type":"journal-article","article-title":"Study of association between corneal shape parameters and axial length elongation during orthokeratology using image-pro plus software","volume":"24","author":"Wang","year":"2024","journal-title":"BMC Ophthalmol."},{"key":"pmbae2b47bib38","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2024.102136","type":"journal-article","article-title":"Altering optical zone diameter, reverse curve width, and compression factor: impacts on visual performance and axial elongation in orthokeratology","volume":"47","author":"Wu","year":"2024","journal-title":"Contact Lens Anterior Eye"},{"key":"pmbae2b47bib39","doi-asserted-by":"publisher","first-page":"6341","DOI":"10.1021\/acs.jcim.5c00726","type":"journal-article","article-title":"Prediction of ligand-receptor interactions based on CatBoost and deep forest and their application in cell-cell communication analysis","volume":"65","author":"Wu","year":"2025","journal-title":"J. Chem. Inf. Model."},{"key":"pmbae2b47bib40","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1111\/aos.15662","type":"journal-article","article-title":"Changes of corneal biomechanics in children using orthokeratology and their roles in predicting axial length progression-A prospective 2-year study","volume":"101","author":"Xiang","year":"2023","journal-title":"Acta Ophthalmol."},{"key":"pmbae2b47bib41","doi-asserted-by":"publisher","first-page":"e686","DOI":"10.1111\/aos.14658","type":"journal-article","article-title":"Development and validation of a prediction model for axial length elongation in myopic children treated with overnight orthokeratology","volume":"99","author":"Xu","year":"2020","journal-title":"Acta Ophthalmol."},{"key":"pmbae2b47bib42","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1080\/02713683.2020.1820528","type":"journal-article","article-title":"The effect of relative corneal refractive power shift distribution on axial length growth in myopic children undergoing orthokeratology treatment","volume":"46","author":"Yang","year":"2021","journal-title":"Curr. Eye Res."},{"key":"pmbae2b47bib43","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2025.102400","type":"journal-article","article-title":"Therapeutic efficacy of orthokeratology lenses with different back optic zone diameters in myopia control: a systematic review and meta-analysis","volume":"48","author":"Yang","year":"2025","journal-title":"Contact Lens Anterior Eye"},{"key":"pmbae2b47bib44","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2023.102081","type":"journal-article","article-title":"Deep neural network with self-attention based automated determination system for treatment zone and peripheral steepened zone in orthokeratology for adolescent myopia","volume":"47","author":"Zhang","year":"2024","journal-title":"Contact Lens Anterior Eye"},{"key":"pmbae2b47bib45","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1167\/tvst.11.2.18","type":"journal-article","article-title":"Change in corneal power distribution in orthokeratology: a predictor for the change in axial length","volume":"11","author":"Zhang","year":"2022","journal-title":"Transl Vis. Sci. Technol."},{"key":"pmbae2b47bib46","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2022.101749","type":"journal-article","article-title":"The effect of corneal power distribution on axial elongation in children using three different orthokeratology lens designs","volume":"46","author":"Zhang","year":"2023","journal-title":"Contact Lens Anterior Eye"},{"key":"pmbae2b47bib47","doi-asserted-by":"publisher","first-page":"4514","DOI":"10.1167\/iovs.14-13935","type":"journal-article","article-title":"Central and peripheral corneal power change in myopic orthokeratology and its relationship with 2-year axial length change","volume":"56","author":"Zhong","year":"2015","journal-title":"Investigative Ophthalmol. Vis. Sci."},{"key":"pmbae2b47bib48","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.18240\/ijo.2022.08.15","type":"journal-article","article-title":"Photopic pupil size change in myopic orthokeratology and its influence on axial length elongation","volume":"15","author":"Zhu","year":"2022","journal-title":"Int. J. Ophthalmol."}],"container-title":["Physics in Medicine &amp; Biology"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/ae2b47","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/ae2b47\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/ae2b47","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/ae2b47\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/ae2b47\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/ae2b47\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/ae2b47\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/ae2b47\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T07:14:44Z","timestamp":1767078884000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/ae2b47"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,30]]},"references-count":48,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12,30]]},"published-print":{"date-parts":[[2026,1,14]]}},"URL":"https:\/\/doi.org\/10.1088\/1361-6560\/ae2b47","relation":{},"ISSN":["0031-9155","1361-6560"],"issn-type":[{"value":"0031-9155","type":"print"},{"value":"1361-6560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,30]]},"assertion":[{"value":"Artificial intelligence for predicting the axial length response of orthokeratology in myopic children","name":"article_title","label":"Article Title"},{"value":"Physics in Medicine & Biology","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2025 The Author(s). Published on behalf of Institute of Physics and Engineering in Medicine by IOP Publishing Ltd","name":"copyright_information","label":"Copyright Information"},{"value":"2025-07-22","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2025-12-10","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2025-12-30","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}