{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T23:38:36Z","timestamp":1792712316251,"version":"4.5.0"},"reference-count":0,"publisher":"IOP Publishing","license":[{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phys. Med. Biol."],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Objective&amp;#xD;Magnetic resonance-integrated proton therapy (MRiPT) offers the potential for high-precision, image-guided particle therapy but is challenged by magnetic field (MF)-induced proton beam deflection and radiation field deformation. Unless compensated for, these effects compromise dose conformity and prohibit clinical implementation. This work aims to develop and experimentally validate a spot-wise compensation method capable of restoring proton dose distributions in the presence of a measured 3D magnetic vector field map within a clinical treatment planning system (TPS).&amp;#xD;Approach&amp;#xD;A spot-wise compensation framework was implemented in a research version of RayStation, a TPS commercially available for clinical use. The method compensates both lateral beam deflection and MF-induced radiation field deformation by shifting individual pencil-beam spots based on displacement vectors derived from dose calculations in water phantoms using the measured MF of an in-beam MR scanner integrated with a horizontal proton beamline. Two complementary strategies were implemented: a patient-specific approach based on plan-specific displacement calculations, and a generic approach using precomputed displacement maps derived from a reference phantom. Compensation performance was evaluated in representative clinical cases. Dose distributions were experimentally validated using 2D ionisation chamber array measurements.&amp;#xD;Main Results&amp;#xD;Both compensation methods effectively restored target coverage, dose homogeneity, and organ-at-risk sparing to the level of no-MF reference plans. The patient-specific method generally achieved a higher performance, whereas the generic compensation method enabled rapid automated correction with sufficient accuracy for clinical workflows involving deep-seated tumours. Local \u03b3-analysis demonstrated excellent agreement between measured and calculated doses, with pass rates exceeding 98.5% for 3%\/3 mm criteria.&amp;#xD;Significance&amp;#xD;This work demonstrates that compensation of MF-induced proton beam deflection and field deformation can be achieved entirely within a research version of the RayStation TPS using measured, MR scanner-specific MF data. The proposed method provides a scalable, robust framework for future  MRiPT clinical applications.&amp;#xD;<\/jats:p>","DOI":"10.1088\/1361-6560\/aeb84d","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T22:52:42Z","timestamp":1792709562000},"source":"Crossref","is-referenced-by-count":0,"title":["Spot-wise compensation of proton beam deflection and radiation field deformation in the transverse magnetic field of an in-beam MR scanner using a research version of a commercial treatment planning system"],"prefix":"10.1088","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2904-267X","authenticated-orcid":false,"given":"Marisa","family":"Cobanaj","sequence":"first","affiliation":[{"name":"OncoRay - National Center for Radiation Research in Oncology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1850-7382","authenticated-orcid":false,"given":"Erik","family":"Traneus","sequence":"additional","affiliation":[{"name":"RaySearch Laboratories AB"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0707-0856","authenticated-orcid":false,"given":"Felix","family":"Horst","sequence":"additional","affiliation":[{"name":"OncoRay - National Center for Radiation Research in Oncology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna Jeanne","family":"Godino Padre","sequence":"additional","affiliation":[{"name":"OncoRay - National Center for Radiation Research in Oncology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Menkel","sequence":"additional","affiliation":[{"name":"OncoRay - National Center for Radiation Research in Oncology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Trnkova","sequence":"additional","affiliation":[{"name":"Czech Technical University in Prague"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aswin L","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"OncoRay - National Center for Radiation Research in Oncology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franciska","family":"Lebbink","sequence":"additional","affiliation":[{"name":"OncoRay - National Center for Radiation Research in Oncology"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2026,10,22]]},"container-title":["Physics in Medicine &amp; Biology"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aeb84d","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aeb84d\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aeb84d\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aeb84d\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T22:52:42Z","timestamp":1792709562000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6560\/aeb84d"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,22]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1088\/1361-6560\/aeb84d","relation":{},"ISSN":["0031-9155","1361-6560"],"issn-type":[{"value":"0031-9155","type":"print"},{"value":"1361-6560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,22]]}}}