{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T12:20:11Z","timestamp":1788006011366,"version":"build-2784847793"},"reference-count":41,"publisher":"IOP Publishing","issue":"5","license":[{"start":{"date-parts":[[2017,4,12]],"date-time":"2017-04-12T00:00:00Z","timestamp":1491955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/publishingsupport.iopscience.iop.org\/iop-standard\/v1"},{"start":{"date-parts":[[2017,4,12]],"date-time":"2017-04-12T00:00:00Z","timestamp":1491955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100005416","name":"The Research Council of Norway","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Sensocure AS"}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Physiol. Meas."],"published-print":{"date-parts":[[2017,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Objective<\/jats:italic>\n                    : Bioimpedance has been used to investigate changes in electrical parameters during ischemia in various tissues. The small intestine is a multi-layered structure, with several distinct tissue types, and ischemia related changes occur at different times in the different intestinal layers. When investigating how the electrical properties in the small intestine is affected by ischemia, some researchers have used\n                    <jats:italic>ex vivo<\/jats:italic>\n                    models while others have used\n                    <jats:italic>in vivo<\/jats:italic>\n                    models. In this study, we compare ischemic time development of electrical parameters in ischemic\n                    <jats:italic>in vivo<\/jats:italic>\n                    versus\n                    <jats:italic>ex vivo<\/jats:italic>\n                    small intestine.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Approach<\/jats:italic>\n                    : Measurements were performed using a two-electrode setup, with a Solartron 1260\/1294 impedance gain-phase analyser. Electrodes were placed on the surface of ischemic pig jejunum, applying a voltage and measuring the resulting electrical admittance. In each pig, 4 segments of the jejunum were made ischemic by clamping the mesenteric arteries and veins, resulting in a 30\u2009cm central zone of warm ischemia and edema. The\n                    <jats:italic>in vivo<\/jats:italic>\n                    part of the experiment lasted 10\u2009h, after which 3 pieces of perfused small intestine were resected, stored in Ringer-acetat at 38 \u00b0C, and measured during a 10\u2009h\n                    <jats:italic>ex vivo<\/jats:italic>\n                    experiment.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Main results and significance<\/jats:italic>\n                    : We found significant differences (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009\u2009&lt;\u2009\u20090.0001) between the values of electric parameters when comparing the\n                    <jats:italic>in vivo<\/jats:italic>\n                    and\n                    <jats:italic>ex vivo<\/jats:italic>\n                    measurements as a function of ischemic time development. We also observed some similarities in the trends.\n                    <jats:italic>In vivo<\/jats:italic>\n                    , we measured an overall decrease in impedance during the duration of the experiment, probably as a result from the formation of edema.\n                    <jats:italic>Ex vivo<\/jats:italic>\n                    , the low frequency impedance increased initially for approximately 3\u2009h before starting to decrease.\n                  <\/jats:p>","DOI":"10.1088\/1361-6579\/aa67b7","type":"journal-article","created":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T10:15:13Z","timestamp":1490004913000},"page":"715-728","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":12,"title":["Ischemic small intestine\u2014\n                    <i>in vivo<\/i>\n                    versus\n                    <i>ex vivo<\/i>\n                    bioimpedance measurements"],"prefix":"10.1088","volume":"38","author":[{"given":"Runar J","family":"Strand-Amundsen","sequence":"first","affiliation":[{"name":"Oslo University Hospital\u2014Rikshospitalet"},{"name":"University of Oslo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik M","family":"Reims","sequence":"additional","affiliation":[{"name":"Oslo University Hospital\u2014Rikshospitalet"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Tronstad","sequence":"additional","affiliation":[{"name":"Oslo University Hospital\u2014Rikshospitalet"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e5vard","family":"Kalv\u00f8y","sequence":"additional","affiliation":[{"name":"Oslo University Hospital\u2014Rikshospitalet"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d8rjan G","family":"Martinsen","sequence":"additional","affiliation":[{"name":"Oslo University Hospital\u2014Rikshospitalet"},{"name":"University of Oslo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan O","family":"H\u00f8getveit","sequence":"additional","affiliation":[{"name":"Oslo University Hospital\u2014Rikshospitalet"},{"name":"University of Oslo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom E","family":"Ruud","sequence":"additional","affiliation":[{"name":"Oslo University Hospital\u2014Rikshospitalet"},{"name":"Baerum Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tor I","family":"T\u00f8nnessen","sequence":"additional","affiliation":[{"name":"Oslo University Hospital\u2014Rikshospitalet"},{"name":"University of Oslo\u2014Rikshospitalet"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2017,4,12]]},"reference":[{"key":"pmeaaa67b7bib001","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1136\/jcp.s3-11.1.68","type":"journal-article","article-title":"Ischaemic bowel disease","volume":"11","author":"Alschibaja","year":"1977","journal-title":"J. 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All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2016-12-08","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2017-03-20","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2017-04-12","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}