{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T13:04:39Z","timestamp":1779541479956,"version":"3.53.1"},"reference-count":18,"publisher":"IOP Publishing","issue":"1","license":[{"start":{"date-parts":[[2017,12,28]],"date-time":"2017-12-28T00:00:00Z","timestamp":1514419200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/publishingsupport.iopscience.iop.org\/iop-standard\/v1"},{"start":{"date-parts":[[2017,12,28]],"date-time":"2017-12-28T00:00:00Z","timestamp":1514419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"name":"Jubil\u00e4umsfond, \u00d6sterreichische Nationalbank"}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Physiol. Meas."],"published-print":{"date-parts":[[2018,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Objective<\/jats:italic>\n                    : In neonates, a patent ductus arteriosus (DA) may be associated with severe complications. We used near-infrared spectroscopy (NIRS) with venous occlusion to investigate the influence of an open DA on peripheral muscle oxygenation\/perfusion in preterm neonates.\n                    <jats:italic>Approach<\/jats:italic>\n                    : We analyzed secondary outcome parameters collected as part of prospective observational studies. NIRS measurements were performed between the first and third day of life. Arterial oxygen saturation (SaO\n                    <jats:sub>2<\/jats:sub>\n                    ) and heart rate (HR) were monitored by pulse oximetry on the ipsilateral foot. Venous occlusion was performed with a blood pressure cuff on the thigh. Tissue oxygenation index (TOI), hemoglobin flow (Hbflow), oxygen delivery (DO\n                    <jats:sub>2<\/jats:sub>\n                    ), oxygen consumption (VO\n                    <jats:sub>2<\/jats:sub>\n                    ), mixed venous oxygenation (SvO\n                    <jats:sub>2<\/jats:sub>\n                    ), and fractional oxygen extraction (FOE) were assessed. Echocardiography was performed within plus\/minus 6\u2009h from NIRS measurements.\n                    <jats:italic>Main results<\/jats:italic>\n                    : Twenty-eight neonates were included. In neonates with open DA (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009\u2009=\u2009\u200915), the FOE was significantly higher (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009\u2009=\u2009\u20090.046). DA diameter correlated negatively with SvO\n                    <jats:sub>2<\/jats:sub>\n                    (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009\u2009=\u2009\u2009\u22120.413,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009\u2009=\u2009\u20090.032) and positively with FOE (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009\u2009=\u2009\u20090.417,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009\u2009=\u2009\u20090.030). In neonates with open DA, SaO\n                    <jats:sub>2<\/jats:sub>\n                    was significantly lower (p\u2009\u2009=\u2009\u20090.041). DA diameter correlated negatively with SaO\n                    <jats:sub>2<\/jats:sub>\n                    (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009\u2009=\u2009\u2009\u22120.377,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009\u2009=\u2009\u20090.048) and positively with HR (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009\u2009=\u2009\u20090.489,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009\u2009=\u2009\u20090.010).\n                    <jats:italic>Significance<\/jats:italic>\n                    : Our results showed that an open DA influences peripheral muscle oxygenation in preterm neonates.\n                  <\/jats:p>","DOI":"10.1088\/1361-6579\/aa9c3b","type":"journal-article","created":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T12:15:12Z","timestamp":1511266512000},"page":"015003","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Influence of ductus arteriosus on peripheral muscle oxygenation and perfusion in neonates"],"prefix":"10.1088","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3932-665X","authenticated-orcid":false,"given":"Lukas P","family":"Mileder","sequence":"first","affiliation":[{"name":"Medical University of Graz"},{"name":"Medical University of Graz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tessa","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Medical University of Graz"},{"name":"University of Munich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nariae","family":"Baik-Schneditz","sequence":"additional","affiliation":[{"name":"Medical University of Graz"},{"name":"Medical University of Graz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmin","family":"Pansy","sequence":"additional","affiliation":[{"name":"Medical University of Graz"},{"name":"Medical University of Graz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Schwaberger","sequence":"additional","affiliation":[{"name":"Medical University of Graz"},{"name":"Medical University of Graz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinna","family":"Binder-Heschl","sequence":"additional","affiliation":[{"name":"Medical University of Graz"},{"name":"Medical University of Graz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berndt","family":"Urlesberger","sequence":"additional","affiliation":[{"name":"Medical University of Graz"},{"name":"Medical University of Graz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Pichler","sequence":"additional","affiliation":[{"name":"Medical University of Graz"},{"name":"Medical University of Graz"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2017,12,28]]},"reference":[{"key":"pmeaaa9c3bbib001","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1159\/000092870","type":"journal-article","article-title":"Mechanisms regulating the ductus arteriosus","volume":"89","author":"Clyman","year":"2006","journal-title":"Biol. 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All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2017-07-14","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2017-11-21","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2017-12-28","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}