{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T17:14:26Z","timestamp":1778778866288,"version":"3.51.4"},"reference-count":37,"publisher":"IOP Publishing","issue":"11","license":[{"start":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:00:00Z","timestamp":1699228800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:00:00Z","timestamp":1699228800000},"content-version":"tdm","delay-in-days":5,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100002790","name":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"crossref","award":["RGPIN-2020-04057"],"award-info":[{"award-number":["RGPIN-2020-04057"]}],"id":[{"id":"10.13039\/501100002790","id-type":"DOI","asserted-by":"crossref"}]},{"name":"John D Petrie QC Memorial Scholarship"},{"name":"Alberta Summer Innovates"},{"name":"Kinesiology Undergraduate Research Scholarship"}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Physiol. Meas."],"published-print":{"date-parts":[[2023,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Objective.<\/jats:italic>\n                    To evaluate sex differences in the reliability of absolute and relative cerebral blood velocity (CBv) during concurrent supine cycling with lower body negative pressure (LBNP).\n                    <jats:italic>Approach<\/jats:italic>\n                    . A total of 19 participants (11 females; aged 20\u201333 years) completed five testing sessions, occurring on 7 d intervals. Visit 1 was a maximal-ramp-cycle test to ascertain peak CBv wattage. During visits 2\u20135, supine cycling protocol occurred at individualized peak CBv wattages with progressive decreases in LBNP from 0 to \u221220, \u221240, \u221260, \u221270, and \u221280 Torr. Menstrual cycle day was self-reported via the Rhinessa Women\u2019s Questionnaire. Transcranial Doppler ultrasound insonated bilateral middle cerebral artery velocity (MCAv). Two-way ANOVA assessed potential day- and sex-differences at each LBNP stage. Reliability was determined using intraclass correlation coefficients (ICC) and coefficient of variation (CoV).\n                    <jats:italic>Main results<\/jats:italic>\n                    . For all physiological measures, no main-effects were present for day- or interaction-terms (\n                    <jats:italic>p<\/jats:italic>\n                    &gt; 0.067; negligible-to-small effect sizes), while sex differences were noted for MCAv, blood pressure, and heart rate (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.046). Across visits, males and females displayed excellent and good-to-excellent levels of reliability for MCAv metrics, respectively (ICC range: 0.745\u20130.999; CoV range: 0.33%\u20139.90%).\n                    <jats:italic>Significance<\/jats:italic>\n                    . During the current investigation, both relative and absolute CBv demonstrated high reliability in both male and female participants during a supine LBNP cycling protocol. An exploratory analysis revealed increased variance was found in female participants dependent on contraceptive use. Despite this, results indicate future LBNP studies may include females at any menstrual cycle stage.\n                  <\/jats:p>","DOI":"10.1088\/1361-6579\/ad0425","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T18:32:53Z","timestamp":1697567573000},"page":"114001","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Influence of sex on the reliability of cerebral blood velocity regulation during lower body negative pressure and supine cycling with considerations of the menstrual cycle"],"prefix":"10.1088","volume":"44","author":[{"given":"Nathan E","family":"Johnson","sequence":"first","affiliation":[{"name":"University of Calgary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9756-5793","authenticated-orcid":false,"given":"Joel S","family":"Burma","sequence":"additional","affiliation":[{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jina","family":"Seok","sequence":"additional","affiliation":[{"name":"University of Calgary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren N","family":"Miutz","sequence":"additional","affiliation":[{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Dayton"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan D","family":"Smirl","sequence":"additional","affiliation":[{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"},{"name":"University of Calgary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"266","published-online":{"date-parts":[[2023,11,6]]},"reference":[{"key":"pmeaad0425bib1","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1152\/japplphysiol.00854.2014","type":"journal-article","article-title":"Transcranial doppler ultrasound: valid, invalid, or both?","volume":"117","author":"Ainslie","year":"2014","journal-title":"J. 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