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When particles are unbiased in their runs along dense filament networks, encounters are shown to be well approximated by a continuum run-and-tumble model. For biased particles, regions of convergent filament orientation serve as traps that slow the overall spatial exploration but can allow for faster encounter rates by funneling particles into regions of reduced dimensionality. These findings provide a framework for estimating intracellular encounter kinetics, highlighting the role of key physical features such as the effective diffusivity, run times, and network architecture.<\/jats:p>","DOI":"10.1088\/1478-3975\/ae5d10","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T22:55:29Z","timestamp":1775688929000},"page":"026010","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Encounter times of intermittently running particles"],"prefix":"10.1088","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3068-9527","authenticated-orcid":true,"given":"Lizzy","family":"Teryoshin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8557-3921","authenticated-orcid":false,"given":"Mario","family":"Hidalgo-Soria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4139-9209","authenticated-orcid":true,"given":"Elena F","family":"Koslover","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"pbae5d10bib1","first-page":"541","type":"book","article-title":"Searching through cellular landscapes","author":"Koslover","year":"2024"},{"key":"pbae5d10bib2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.237016","type":"journal-article","article-title":"The role of microtubules in secretory protein transport","volume":"133","author":"Fourriere","year":"2020","journal-title":"J. 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