{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:14:23Z","timestamp":1789755263319,"version":"4.0.1"},"reference-count":45,"publisher":"IOP Publishing","issue":"1","license":[{"start":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:00:00Z","timestamp":1512518400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/publishingsupport.iopscience.iop.org\/iop-standard\/v1"},{"start":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:00:00Z","timestamp":1512518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek","doi-asserted-by":"crossref","award":["G.066213"],"award-info":[{"award-number":["G.066213"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Hermes Fonds","award":["141243"],"award-info":[{"award-number":["141243"]}]},{"DOI":"10.13039\/501100003132","name":"Agentschap voor Innovatie door Wetenschap en Technologie","doi-asserted-by":"crossref","award":["150432"],"award-info":[{"award-number":["150432"]}],"id":[{"id":"10.13039\/501100003132","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["J. Neural Eng."],"published-print":{"date-parts":[[2018,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Objective<\/jats:italic>\n                    . Electrically evoked auditory steady-state responses (EASSRs) are potentially useful for objective cochlear implant (CI) fitting and follow-up of the auditory maturation in infants and children with a CI. EASSRs are recorded in the electro-encephalogram (EEG) in response to electrical stimulation with continuous pulse trains, and are distorted by significant CI artifacts related to this electrical stimulation. The aim of this study is to evaluate a CI artifacts attenuation method based on independent component analysis (ICA) for three EASSR datasets.\n                    <jats:italic>Approach<\/jats:italic>\n                    . ICA has often been used to remove CI artifacts from the EEG to record transient auditory responses, such as cortical evoked auditory potentials. Independent components (ICs) corresponding to CI artifacts are then often manually identified. In this study, an ICA based CI artifacts attenuation method was developed and evaluated for EASSR measurements with varying CI artifacts and EASSR characteristics. Artifactual ICs were automatically identified based on their spectrum.\n                    <jats:italic>Main results<\/jats:italic>\n                    . For 40 Hz amplitude modulation (AM) stimulation at comfort level, in high SNR recordings, ICA succeeded in removing CI artifacts from all recording channels, without distorting the EASSR. For lower SNR recordings, with 40 Hz AM stimulation at lower levels, or 90 Hz AM stimulation, ICA either distorted the EASSR or could not remove all CI artifacts in most subjects, except for two of the seven subjects tested with low level 40 Hz AM stimulation. Noise levels were reduced after ICA was applied, and up to 29 ICs were rejected, suggesting poor ICA separation quality.\n                    <jats:italic>Significance<\/jats:italic>\n                    . We hypothesize that ICA is capable of separating CI artifacts and EASSR in case the contralateral hemisphere is EASSR dominated. For small EASSRs or large CI artifact amplitudes, ICA separation quality is insufficient to ensure complete CI artifacts attenuation without EASSR distortion.\n                  <\/jats:p>","DOI":"10.1088\/1741-2552\/aa87ce","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T12:15:03Z","timestamp":1512562503000},"page":"016006","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":16,"title":["Independent component analysis for cochlear implant artifacts attenuation from electrically evoked auditory steady-state response measurements"],"prefix":"10.1088","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9784-2826","authenticated-orcid":false,"given":"Hanne","family":"Deprez","sequence":"first","affiliation":[{"name":"KU Leuven"},{"name":"KU Leuven"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Gransier","sequence":"additional","affiliation":[{"name":"KU Leuven"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Hofmann","sequence":"additional","affiliation":[{"name":"KU Leuven"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"van Wieringen","sequence":"additional","affiliation":[{"name":"KU Leuven"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Wouters","sequence":"additional","affiliation":[{"name":"KU Leuven"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Moonen","sequence":"additional","affiliation":[{"name":"KU Leuven"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2017,12,6]]},"reference":[{"key":"jneaa87cebib001","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1109\/MSP.2014.2371671","type":"journal-article","article-title":"Sound coding in cochlear implants: from electric pulses to hearing","volume":"32","author":"Wouters","year":"2015","journal-title":"IEEE Signal Process. 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