{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T05:09:38Z","timestamp":1768712978360,"version":"3.49.0"},"reference-count":43,"publisher":"IOP Publishing","issue":"1","license":[{"start":{"date-parts":[[2020,2,12]],"date-time":"2020-02-12T00:00:00Z","timestamp":1581465600000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/publishingsupport.iopscience.iop.org\/iop-standard\/v1"},{"start":{"date-parts":[[2020,2,12]],"date-time":"2020-02-12T00:00:00Z","timestamp":1581465600000},"content-version":"tdm","delay-in-days":11,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"crossref","award":["N01-NS-5-2365"],"award-info":[{"award-number":["N01-NS-5-2365"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000146","name":"Division of Chemical, Bioengineering, Environmental, and Transport Systems","doi-asserted-by":"crossref","award":["1751821"],"award-info":[{"award-number":["1751821"]}],"id":[{"id":"10.13039\/100000146","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"crossref","award":["B2359-C"],"award-info":[{"award-number":["B2359-C"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["J. Neural Eng."],"published-print":{"date-parts":[[2020,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Objective<\/jats:italic>\n                    . This study\u2019s goal was to demonstrate person-specific predictions of the force production capabilities of a paralyzed arm when actuated with a functional electrical stimulation (FES) neuroprosthesis. These predictions allow us to determine, for each hand position in a person\u2019s workspace, if FES activated muscles can produce enough force to hold the arm against gravity and other passive forces, the amount of force the arm can potentially exert on external objects, and in which directions FES can move the arm.\n                    <jats:italic>Approach<\/jats:italic>\n                    . We computed force production predictions for a person with high tetraplegia and an FES neuroprosthesis used to activate muscles in her shoulder and arm. We developed Gaussian process regression models of the force produced at the end of the forearm when stimulating individual muscles at different wrist positions in the person\u2019s workspace. For any given wrist position, we predicted all possible forces a person can produce by any combination of individual muscles. Based on the force predictions, we determined if FES could produce force sufficient to overcome passive forces to hold a wrist position, the maximum force FES could produce in all directions, and the set of directions in which FES could move the arm. To estimate the error in our predictions, we then compared our force predictions based on single-muscle models to the actual forces produced when stimulating combinations of the person\u2019s muscles.\n                    <jats:italic>Main results<\/jats:italic>\n                    . Our models classified the person\u2019s ability to hold static arm positions correctly for 83% (Session #1) and 69% (Session #2) for 39 wrist positions over two sessions. We predicted this person\u2019s ability to produce force at the end of her arm with an RMS error of 5.5 N and the percent of directions for which FES could achieve motion with RMS error of 10%. The accuracy of these predictions is similar to that found in the literature for FES systems with fewer degrees of freedom and fewer muscles.\n                    <jats:italic>Significance<\/jats:italic>\n                    . These person and device-specific predictions of functional capabilities of the arm allow neuroprosthesis developers to set achievable functional objectives for the systems they develop. These predictions can potentially serve as a screening tool for clinicians to use in planning neuroprosthetic interventions, greatly reducing the risk and uncertainty in such interventions.\n                  <\/jats:p>","DOI":"10.1088\/1741-2552\/ab68b3","type":"journal-article","created":{"date-parts":[[2020,1,7]],"date-time":"2020-01-07T17:45:23Z","timestamp":1578419123000},"page":"016051","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Predicting functional force production capabilities of upper extremity functional electrical stimulation neuroprostheses: a proof of concept study"],"prefix":"10.1088","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8583-0705","authenticated-orcid":false,"given":"Eric M","family":"Schearer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek N","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"266","published-online":{"date-parts":[[2020,2,12]]},"reference":[{"key":"jneab68b3bib001","doi-asserted-by":"publisher","first-page":"1821","DOI":"10.1016\/S0140-6736(17)30601-3","type":"journal-article","article-title":"Restoration of reaching and grasping movements through brain-controlled muscle stimulation in a person with tetraplegia: a proof-of-concept demonstration","volume":"389","author":"Ajiboye","year":"2017","journal-title":"Lancet"},{"key":"jneab68b3bib002","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1089\/neu.2004.21.1371","type":"journal-article","article-title":"Targeting recovery: priorities of the spinal cord-injured population","volume":"21","author":"Anderson","year":"2004","journal-title":"J. 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