{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T04:31:15Z","timestamp":1768710675445,"version":"3.49.0"},"reference-count":29,"publisher":"IOP Publishing","issue":"2","license":[{"start":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T00:00:00Z","timestamp":1586390400000},"content-version":"vor","delay-in-days":8,"URL":"https:\/\/publishingsupport.iopscience.iop.org\/iop-standard\/v1"},{"start":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T00:00:00Z","timestamp":1586390400000},"content-version":"tdm","delay-in-days":8,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003626","name":"Defense Acquisition Program Administration","doi-asserted-by":"crossref","award":["UD170030ID"],"award-info":[{"award-number":["UD170030ID"]}],"id":[{"id":"10.13039\/501100003626","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100016275","name":"Seoul National University Bundang Hospital","doi-asserted-by":"crossref","award":["14-2019-002"],"award-info":[{"award-number":["14-2019-002"]}],"id":[{"id":"10.13039\/100016275","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["J. Neural Eng."],"published-print":{"date-parts":[[2020,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Objective.<\/jats:italic>\n                    Obstructive sleep apnea (OSA) is a disorder with a high prevalence rate that may induce serious complications. Recent progress in the area of hypoglossal nerve stimulation has played a role as an alternative to conventional therapies though, some patients having retropalatal collapse still have not benefitted. Therefore, here we propose a new type of upper-airway stimulation, referred to as the palatal implant system, which recovers the upper-airway patency by electrically stimulating the soft palate.\n                    <jats:italic>Approach.<\/jats:italic>\n                    The system consists of two major parts: an implant that stimulates the soft palate through electrodes and an intra-oral device that delivers power and data simultaneously to the implant via an inductive link. Evaluations of the system are conducted in bench-top,\n                    <jats:italic>in vitro<\/jats:italic>\n                    , and\n                    <jats:italic>in vivo<\/jats:italic>\n                    tests to evaluate its feasibility as an OSA treatment, and the potential development of the system is addressed in the discussion section.\n                    <jats:italic>Main results.<\/jats:italic>\n                    In the bench-top test, the power efficiency was 12.4% at\n                    <jats:italic>d<\/jats:italic>\n                    = 5 mm and the system could operate up to 8 mm distance in a bio-medium. Data transmission was also successful at distances ranging 2 to 8 mm within an error margin of 10%. The measured CSC\n                    <jats:sub>c<\/jats:sub>\n                    and the impedance magnitude of the electrode were 62.25 mC cm\n                    <jats:sup>\u22122<\/jats:sup>\n                    and 390 \u03a9, respectively, proving a feasibility of the electrode as a stimluator interface. The system was applied to a rabbit and contraction of the soft palate muscle was recorded via a C-arm fluoroscopy.\n                    <jats:italic>Significance.<\/jats:italic>\n                    As a proof of concept, we suggest and demonstrate the palatal implant system as a new therapy for those undergoing treatment for OSA.\n                  <\/jats:p>","DOI":"10.1088\/1741-2552\/ab7d61","type":"journal-article","created":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T17:16:03Z","timestamp":1583514963000},"page":"026017","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Palatal implant system can provide effective treatment for obstructive sleep apnea by recovering retropalatal patency"],"prefix":"10.1088","volume":"17","author":[{"given":"Jungmin","family":"Seo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seunghyeon","family":"Yun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinyong","family":"Shim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Woo","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9210-9681","authenticated-orcid":false,"given":"Jin-Woo","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong-Whun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2885-043X","authenticated-orcid":false,"given":"Sung June","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"266","published-online":{"date-parts":[[2020,4,9]]},"reference":[{"key":"jneab7d61bib1","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1109\/TCPMT.2011.2178092","type":"journal-article","article-title":"Reliability of liquid crystal polymer air cavity packaging","volume":"2","author":"Aihara","year":"2012","journal-title":"IEEE Trans. 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All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2019-09-12","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2020-03-06","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2020-04-09","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}