{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T17:06:47Z","timestamp":1794330407358,"version":"4.9.0"},"reference-count":63,"publisher":"IOP Publishing","issue":"3","license":[{"start":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T00:00:00Z","timestamp":1715904000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T00:00:00Z","timestamp":1715904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"crossref","award":["2016-03564"],"award-info":[{"award-number":["2016-03564"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"crossref"}]},{"name":"University of Applied Sciences and Arts Northwestern Switzerland"},{"name":"Swedish foundation for strategic research","award":["BD15-0032"],"award-info":[{"award-number":["BD15-0032"]}]},{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"crossref","award":["205320_207491"],"award-info":[{"award-number":["205320_207491"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["J. Neural Eng."],"published-print":{"date-parts":[[2024,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Deep brain stimulation (DBS) is a therapy for Parkinson\u2019s disease (PD) and essential tremor (ET). The mechanism of action of DBS is still incompletely understood. Retrospective group analysis of intra-operative data recorded from ET patients implanted in the ventral intermediate nucleus of the thalamus (Vim) is rare. Intra-operative stimulation tests generate rich data and their use in group analysis has not yet been explored.\n                    <jats:italic>Objective.<\/jats:italic>\n                    To implement, evaluate, and apply a group analysis workflow to generate probabilistic stimulation maps (PSMs) using intra-operative stimulation data from ET patients implanted in Vim.\n                    <jats:italic>Approach.<\/jats:italic>\n                    A group-specific anatomical template was constructed based on the magnetic resonance imaging scans of 6 ET patients and 13 PD patients. Intra-operative test data (total:\n                    <jats:italic>n<\/jats:italic>\n                    = 1821) from the 6 ET patients was analyzed: patient-specific electric field simulations together with tremor assessments obtained by a wrist-based acceleration sensor were transferred to this template. Occurrence and weighted mean maps were generated. Voxels associated with symptomatic response were identified through a linear mixed model approach to form a PSM. Improvements predicted by the PSM were compared to those clinically assessed. Finally, the PSM clusters were compared to those obtained in a multicenter study using data from chronic stimulation effects in ET.\n                    <jats:italic>Main results.<\/jats:italic>\n                    Regions responsible for improvement identified on the PSM were in the posterior sub-thalamic area (PSA) and at the border between the Vim and ventro-oral nucleus of the thalamus (VO). The comparison with literature revealed a center-to-center distance of less than 5 mm and an overlap score (Dice) of 0.4 between the significant clusters. Our workflow and intra-operative test data from 6 ET-Vim patients identified effective stimulation areas in PSA and around Vim and VO, affirming existing medical literature.\n                    <jats:italic>Significance.<\/jats:italic>\n                    This study supports the potential of probabilistic analysis of intra-operative stimulation test data to reveal DBS\u2019s action mechanisms and to assist surgical planning.\n                  <\/jats:p>","DOI":"10.1088\/1741-2552\/ad4742","type":"journal-article","created":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T18:28:51Z","timestamp":1714760931000},"page":"036017","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Probabilistic stimulation mapping from intra-operative thalamic deep brain stimulation data in essential tremor"],"prefix":"10.1088","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3445-576X","authenticated-orcid":true,"given":"Dorian","family":"Vogel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1641-9848","authenticated-orcid":false,"given":"Teresa","family":"Nordin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1340-9093","authenticated-orcid":false,"given":"Stefanie","family":"Feiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0012-7867","authenticated-orcid":true,"given":"Karin","family":"W\u00e5rdell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3262-0867","authenticated-orcid":true,"given":"J\u00e9r\u00f4me","family":"Coste","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4395-5328","authenticated-orcid":false,"given":"Jean-Jacques","family":"Lemaire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5726-6761","authenticated-orcid":false,"given":"Simone","family":"Hemm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2024,5,17]]},"reference":[{"key":"jnead4742bib1","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1159\/000478273","article-title":"Refining the deep brain stimulation target within the limbic globus pallidus internus for Tourette syndrome","volume":"95","author":"Akbarian-Tefaghi","year":"2017","journal-title":"Stereotact. Funct. Neurosurg."},{"key":"jnead4742bib2","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.neuroimage.2017.07.012","article-title":"Subthalamic deep brain stimulation sweet spots and hyperdirect cortical connectivity in Parkinson\u2019s disease","volume":"158","author":"Akram","year":"2017","journal-title":"NeuroImage"},{"key":"jnead4742bib3","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.nicl.2018.01.008","article-title":"Connectivity derived thalamic segmentation in deep brain stimulation for tremor","volume":"18","author":"Akram","year":"2018","journal-title":"NeuroImage Clin."},{"key":"jnead4742bib4","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1109\/TBME.2014.2363494","article-title":"Relationship between neural activation and electric field distribution during deep brain stimulation","volume":"62","author":"\u00c5str\u00f6m","year":"2015","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"jnead4742bib5","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1007\/s11517-011-0842-z","article-title":"Influence of heterogeneous and anisotropic tissue conductivity on electric field distribution in deep brain stimulation","volume":"50","author":"\u00c5str\u00f6m","year":"2012","journal-title":"Med. Biol. Eng. Comput."},{"key":"jnead4742bib6","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1159\/000492230","article-title":"Prediction of electrode contacts for clinically effective deep brain stimulation in essential tremor","volume":"96","author":"\u00c5str\u00f6m","year":"2018","journal-title":"Stereotact. Funct. Neurosurg."},{"key":"jnead4742bib7","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s11517-008-0411-2","article-title":"Method for patient-specific finite element modeling and simulation of deep brain stimulation","volume":"47","author":"Astr\u00f6m","year":"2009","journal-title":"Med. Biol. Eng. Comput."},{"key":"jnead4742bib8","doi-asserted-by":"publisher","first-page":"2457","DOI":"10.1016\/j.neuroimage.2009.09.062","article-title":"The optimal template effect in hippocampus studies of diseased populations","volume":"49","author":"Avants","year":"2010","journal-title":"NeuroImage"},{"key":"jnead4742bib9","doi-asserted-by":"publisher","first-page":"e543","DOI":"10.1212\/WNL.0000000000005956","article-title":"DBS of the PSA and the VIM in essential tremor: a randomized, double-blind, crossover trial","volume":"91","author":"Barbe","year":"2018","journal-title":"Neurology"},{"key":"jnead4742bib10","first-page":"39","article-title":"Chronic VIM thalamic stimulation in Parkinson\u2019s disease, essential tremor and extra-pyramidal dyskinesias","volume":"58","author":"Benabid","year":"1993","journal-title":"Acta Neurochir. Suppl."},{"key":"jnead4742bib11","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1159\/000098600","article-title":"Acute and long-term effects of subthalamic nucleus stimulation in Parkinson\u2019s disease","volume":"62","author":"Benabid","year":"1994","journal-title":"Stereotact. Funct. Neurosurg."},{"key":"jnead4742bib12","doi-asserted-by":"publisher","first-page":"37","DOI":"10.47924\/neurotarget2017137","article-title":"Software for stereotactic surgery planning","volume":"11","author":"Beninca","year":"2017","journal-title":"Neurotarget"},{"key":"jnead4742bib13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1008023","article-title":"OSS-DBS: open-source simulation platform for deep brain stimulation with a comprehensive automated modeling","volume":"16","author":"Butenko","year":"2020","journal-title":"PLoS Comput. Biol."},{"key":"jnead4742bib14","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/j.neuroimage.2006.09.034","article-title":"Patient-specific analysis of the volume of tissue activated during deep brain stimulation","volume":"34","author":"Butson","year":"2007","journal-title":"NeuroImage"},{"key":"jnead4742bib15","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1016\/j.brs.2018.03.009","article-title":"Non-motor outcomes of subthalamic stimulation in Parkinson\u2019s disease depend on location of active contacts","volume":"11","author":"Dafsari","year":"2018","journal-title":"Brain Stimul."},{"key":"jnead4742bib16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000516098","article-title":"Stimulation sweet spot in subthalamic deep brain stimulation\u2014myth or reality? A critical review of literature","volume":"99","author":"de Roquemaurel","year":"2021","journal-title":"Stereotact. Funct. Neurosurg."},{"key":"jnead4742bib17","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1002\/ana.25567","article-title":"Probabilistic sweet spots predict motor outcome for deep brain stimulation in Parkinson disease","volume":"86","author":"Dembek","year":"2019","journal-title":"Ann. Neurol."},{"key":"jnead4742bib18","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.nicl.2016.11.019","article-title":"Probabilistic mapping of deep brain stimulation effects in essential tremor","volume":"13","author":"Dembek","year":"2017","journal-title":"NeuroImage Clin."},{"key":"jnead4742bib19","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1002\/ana.24204","article-title":"Functional anatomy of subthalamic nucleus stimulation in Parkinson disease: STN DBS location and PD","volume":"76","author":"Eisenstein","year":"2014","journal-title":"Ann. Neurol."},{"key":"jnead4742bib20","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1002\/ana.25975","article-title":"Probabilistic mapping of deep brain stimulation: insights from 15 years of therapy","volume":"89","author":"Elias","year":"2021","journal-title":"Ann. Neurol."},{"key":"jnead4742bib21","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1016\/j.neuroimage.2018.09.061","article-title":"Optimization and comparative evaluation of nonlinear deformation algorithms for atlas-based segmentation of DBS target nuclei","volume":"184","author":"Ewert","year":"2019","journal-title":"NeuroImage"},{"key":"jnead4742bib22","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1016\/j.mri.2012.05.001","article-title":"3D slicer as an image computing platform for the quantitative imaging network","volume":"30","author":"Fedorov","year":"2012","journal-title":"J. Magn. Reson."},{"key":"jnead4742bib23","doi-asserted-by":"publisher","first-page":"S102","DOI":"10.1016\/S1053-8119(09)70884-5","article-title":"Unbiased nonlinear average age-appropriate brain templates from birth to adulthood","volume":"47","author":"Fonov","year":"2009","journal-title":"NeuroImage"},{"key":"jnead4742bib24","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1093\/brain\/awp315","article-title":"Reversing cognitive\u2013motor impairments in Parkinson\u2019s disease patients using a computational modelling approach to deep brain stimulation programming","volume":"133","author":"Frankemolle","year":"2010","journal-title":"Brain"},{"key":"jnead4742bib25","doi-asserted-by":"publisher","first-page":"2271","DOI":"10.1088\/0031-9155\/41\/11\/003","article-title":"The dielectric properties of biological tissues: III. Parametric models for the dielectric spectrum of tissues","volume":"41","author":"Gabriel","year":"1996","journal-title":"Phys. Med. Biol."},{"key":"jnead4742bib26","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.parkreldis.2019.05.017","article-title":"Intraoperative test stimulation of the subthalamic nucleus aids postoperative programming of chronic stimulation settings in Parkinson\u2019s disease","volume":"65","author":"Geraedts","year":"2019","journal-title":"Parkinsonism Relat. Disord."},{"key":"jnead4742bib27","doi-asserted-by":"publisher","first-page":"S33","DOI":"10.3233\/JPD-179007","article-title":"My 25 stimulating years with DBS in Parkinson\u2019s disease","volume":"7","author":"Hariz","year":"2017","journal-title":"J. Parkinsons Dis."},{"key":"jnead4742bib28","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.neuroimage.2018.08.068","article-title":"Lead-DBS v2: towards a comprehensive pipeline for deep brain stimulation imaging","volume":"184","author":"Horn","year":"2019","journal-title":"NeuroImage"},{"key":"jnead4742bib29","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1016\/j.neuroimage.2015.08.048","article-title":"Toward a standardized structural\u2013functional group connectome in MNI space","volume":"124","author":"Horn","year":"2016","journal-title":"NeuroImage"},{"key":"jnead4742bib30","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.brs.2016.09.001","article-title":"Role of soft-tissue heterogeneity in computational models of deep brain stimulation","volume":"10","author":"Howell","year":"2017","journal-title":"Brain Stimul."},{"key":"jnead4742bib31","doi-asserted-by":"publisher","first-page":"5212","DOI":"10.1109\/EMBC.2019.8856307","article-title":"Patient-specific simulations of deep brain stimulation electric field with aid of in-house software ELMA","author":"Johansson","year":"2019"},{"key":"jnead4742bib32","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1136\/jnnp-2019-320379","article-title":"Image-based analysis and long-term clinical outcomes of deep brain stimulation for Tourette syndrome: a multisite study","volume":"90","author":"Johnson","year":"2019","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"jnead4742bib33","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.678592","article-title":"Stimulation-induced side effects of deep brain stimulation in the ventralis intermedius and posterior subthalamic area for essential tremor","volume":"12","author":"Kim","year":"2021","journal-title":"Front. Neurol."},{"key":"jnead4742bib34","doi-asserted-by":"publisher","first-page":"724","DOI":"10.3171\/2009.3.JNS09111","article-title":"Microstimulation-induced inhibition as a tool to aid targeting the ventral border of the subthalamic nucleus: clinical article","volume":"111","author":"Lafreniere-Roula","year":"2009","journal-title":"J. Neurosurg."},{"key":"jnead4742bib35","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.jneumeth.2012.11.002","article-title":"Anatomo-clinical atlases correlate clinical data and electrode contact coordinates: application to subthalamic deep brain stimulation","volume":"212","author":"Lalys","year":"2013","journal-title":"J. Neurosci. Methods"},{"key":"jnead4742bib36","doi-asserted-by":"publisher","DOI":"10.1051\/978-2-7598-2576-9","article-title":"Textbook on MRI mapping of the human deep brain: maps and extended 3D analysis","author":"Lemaire","year":"2021"},{"key":"jnead4742bib37","doi-asserted-by":"publisher","first-page":"851","DOI":"10.3389\/fneur.2019.00851","article-title":"MRI atlas of the human deep brain","volume":"10","author":"Lemaire","year":"2019","journal-title":"Front. Neurol."},{"key":"jnead4742bib38","doi-asserted-by":"publisher","first-page":"ons161","DOI":"10.1227\/01.NEU.0000365617.41061.A3","article-title":"Anatomy of the human thalamus based on spontaneous contrast and microscopic voxels in high-field magnetic resonance imaging","volume":"66","author":"Lemaire","year":"2010","journal-title":"Oper. Neurosurg."},{"key":"jnead4742bib39","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1038\/s41582-018-0128-2","article-title":"Deep brain stimulation: current challenges and future directions","volume":"15","author":"Lozano","year":"2019","journal-title":"Nat. Rev. Neurol."},{"key":"jnead4742bib40","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1006\/nimg.2000.0552","article-title":"Visualization of subthalamic nuclei with cortex attenuated inversion recovery MR imaging","volume":"11","author":"Magnotta","year":"2000","journal-title":"NeuroImage"},{"key":"jnead4742bib41","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2021.102846","article-title":"Connectivity correlates to predict essential tremor deep brain stimulation outcome: evidence for a common treatment pathway","volume":"32","author":"Middlebrooks","year":"2021","journal-title":"NeuroImage Clin."},{"key":"jnead4742bib42","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.parkreldis.2018.09.004","article-title":"Benefits and risks of unilateral and bilateral ventral intermediate nucleus deep brain stimulation for axial essential tremor symptoms","volume":"60","author":"Mitchell","year":"2019","journal-title":"Parkinsonism Relat. Disord."},{"key":"jnead4742bib43","doi-asserted-by":"publisher","DOI":"10.3109\/9781420016796","author":"Morel","year":"2007","edition":"1st edn"},{"key":"jnead4742bib44","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2023.119862","article-title":"Lead-DBS v3.0: mapping deep brain stimulation effects to local anatomy and global networks","volume":"268","author":"Neudorfer","year":"2023","journal-title":"NeuroImage"},{"key":"jnead4742bib45","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1016\/j.brs.2019.05.001","article-title":"Directional stimulation of subthalamic nucleus sweet spot predicts clinical efficacy: proof of concept","volume":"12","author":"Nguyen","year":"2019","journal-title":"Brain Stimul."},{"key":"jnead4742bib46","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1016\/j.brs.2022.08.010","article-title":"Probabilistic maps for deep brain stimulation\u2014impact of methodological differences","volume":"15","author":"Nordin","year":"2022","journal-title":"Brain Stimul."},{"key":"jnead4742bib47","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2019.102026","article-title":"White matter tracing combined with electric field simulation\u2014a patient-specific approach for deep brain stimulation","volume":"24","author":"Nordin","year":"2019","journal-title":"NeuroImage Clin."},{"key":"jnead4742bib48","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1002\/ana.26324","article-title":"Probabilistic mapping reveals optimal stimulation site in essential tremor","volume":"91","author":"Nowacki","year":"2022","journal-title":"Ann. Neurol."},{"key":"jnead4742bib49","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1227\/01.NEU.0000180960.75347.11","article-title":"Statistical analysis of 168 bilateral subthalamic nucleus implantations by means of the probabilistic functional atlas","volume":"57","author":"Nowinski","year":"2005","journal-title":"Oper. Neurosurg."},{"key":"jnead4742bib50","doi-asserted-by":"publisher","first-page":"995","DOI":"10.3171\/2011.7.JNS11250","article-title":"Multi-institutional evaluation of deep brain stimulation targeting using probabilistic connectivity-based thalamic segmentation: clinical article","volume":"115","author":"Pouratian","year":"2011","journal-title":"J. Neurosurg."},{"key":"jnead4742bib51","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1002\/mdc3.13490","article-title":"Benefits and risks of a Staged\u2010Bilateral VIM versus unilateral VIM DBS for essential tremor","volume":"9","author":"Prakash","year":"2022","journal-title":"Mov. Disord. Clin. Pract."},{"key":"jnead4742bib52","author":"Schaltenbrand","year":"1977"},{"key":"jnead4742bib53","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1515\/cdbme-2015-0117","article-title":"Use of quantitative tremor evaluation to enhance target selection during deep brain stimulation surgery for essential tremor","volume":"1","author":"Shah","year":"2015","journal-title":"Curr. Direct. Biomed. Eng."},{"key":"jnead4742bib54","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1007\/s11517-016-1559-9","article-title":"Intraoperative acceleration measurements to quantify improvement in tremor during deep brain stimulation surgery","volume":"55","author":"Shah","year":"2017","journal-title":"Med. Biol. Eng. Comput."},{"key":"jnead4742bib55","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1007\/s11517-020-02130-y","article-title":"Stimulation maps: visualization of results of quantitative intraoperative testing for deep brain stimulation surgery","volume":"58","author":"Shah","year":"2020","journal-title":"Med. Biol. Eng. Comput."},{"key":"jnead4742bib56","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2020.117018","article-title":"Deep brain stimulation: imaging on a group level","volume":"219","author":"Treu","year":"2020","journal-title":"NeuroImage"},{"key":"jnead4742bib57","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1016\/j.brs.2011.10.007","article-title":"Direct stereotactic targeting of the ventrointermediate nucleus of the thalamus based on anatomic 1.5-T MRI mapping with a white matter attenuated inversion recovery (WAIR) sequence","volume":"5","author":"Vassal","year":"2012","journal-title":"Brain Stimul."},{"key":"jnead4742bib58","article-title":"#26250\u2014stereoslicer, A plugin for 3Dslicer to handle data from stereotactic surgeries","author":"Vogel","year":"2021a"},{"key":"jnead4742bib59","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2020.102271","article-title":"Anatomical brain structures normalization for deep brain stimulation in movement disorders","volume":"27","author":"Vogel","year":"2020","journal-title":"NeuroImage Clin."},{"key":"jnead4742bib60","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1007\/978-3-030-64610-3_16","article-title":"Atlas optimization for deep brain stimulation","author":"Vogel","year":"2021b"},{"key":"jnead4742bib61","first-page":"148","article-title":"Patient-specific brain modelling for deep brain stimulation simulations","author":"W\u00e5rdell","year":"2013"},{"key":"jnead4742bib62","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1007\/8415_2011_104","article-title":"Patient-specific modeling and simulation of deep brain stimulation","author":"W\u00e5rdell","year":"2011"},{"key":"jnead4742bib63","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/j.neuroimage.2006.09.026","article-title":"A three-dimensional, histological and deformable atlas of the human basal ganglia. I. Atlas construction based on immunohistochemical and MRI data","volume":"34","author":"Yelnik","year":"2007","journal-title":"NeuroImage"}],"container-title":["Journal of Neural Engineering"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ad4742","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ad4742\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ad4742","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ad4742\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ad4742\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ad4742\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ad4742\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ad4742\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T04:19:48Z","timestamp":1715919588000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ad4742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,17]]},"references-count":63,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,5,17]]},"published-print":{"date-parts":[[2024,6,1]]}},"URL":"https:\/\/doi.org\/10.1088\/1741-2552\/ad4742","relation":{},"ISSN":["1741-2560","1741-2552"],"issn-type":[{"value":"1741-2560","type":"print"},{"value":"1741-2552","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,17]]},"assertion":[{"value":"Probabilistic stimulation mapping from intra-operative thalamic deep brain stimulation data in essential tremor","name":"article_title","label":"Article Title"},{"value":"Journal of Neural Engineering","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2024 The Author(s). Published by IOP Publishing Ltd","name":"copyright_information","label":"Copyright Information"},{"value":"2023-11-17","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-05-03","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-05-17","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}