{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:15:01Z","timestamp":1793394901229,"version":"4.5.0"},"reference-count":76,"publisher":"IOP Publishing","issue":"6","license":[{"start":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T00:00:00Z","timestamp":1765238400000},"content-version":"vor","delay-in-days":8,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T00:00:00Z","timestamp":1765238400000},"content-version":"tdm","delay-in-days":8,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"crossref","award":["36C25021C0228"],"award-info":[{"award-number":["36C25021C0228"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["T32EB004314-21"],"award-info":[{"award-number":["T32EB004314-21"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000185","name":"Defense Advanced Research Projects Agency","doi-asserted-by":"crossref","award":["N66001-15-C-4014"],"award-info":[{"award-number":["N66001-15-C-4014"]}],"id":[{"id":"10.13039\/100000185","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["J. Neural Eng."],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Objective.<\/jats:italic>\n                    Implanted electrodes for nerve stimulation and myoelectric recording facilitate bidirectional sensory feedback and control for neuromuscular conditions such as limb loss. While increasing implanted electrode channel count offers potential benefits, it also presents engineering and implementation challenges. This case study examines how increasing implanted electrode channel count affects sensory perception and myoelectric controller performance, thereby supporting the value of these advancements.\n                    <jats:italic>Approach.<\/jats:italic>\n                    One participant with upper extremity transradial limb loss received a percutaneous implanted system with two 8-channel extraneural cuff electrodes on the median and ulnar nerves, totaling 16 stimulating channels. The individual later received a wirelessly connected implanted system featuring four 16-channel extraneural cuff electrodes on the median, ulnar, and radial nerves, totaling 64 stimulation channels, and four tetra-intramuscular (TIM) recording electrodes in residual muscles, totaling 32 sensing channels configured into 16 bipolar pairs. To compare sensory perception between the 16- and 64-channel stimulation systems, we assessed cumulative percept location coverage and the number of unique percept locations, estimated through hierarchical clustering. We compared performance across three myoelectric control algorithms that mapped 8, 10, or 14 intramuscular signal inputs through an artificial neural network to control a virtual hand in 4 degrees-of-freedom (DOFs), with simultaneous, independent, and proportional control.\n                    <jats:italic>Main results.<\/jats:italic>\n                    Increasing stimulation channel count expanded cumulative percept location coverage and increased the number of unique percept locations on the hand. Adding intramuscular recording channel inputs improved 4-DOF myoelectric control of a virtual hand, increasing target posture match percentage and path efficiency.\n                    <jats:italic>Significance.<\/jats:italic>\n                    This case study demonstrates that increasing the number of implanted electrodes can advance sensory restoration and myoelectric control for bidirectional upper limb prostheses. Continued development of more complex systems with higher channel counts may further improve outcomes for individuals with limb loss and enhance the function of sensorimotor restoration systems.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Trial registration:<\/jats:bold>\n                    ClinicalTrials.gov ID: NCT04430218, 2020-06-30\n                  <\/jats:p>","DOI":"10.1088\/1741-2552\/ae24ae","type":"journal-article","created":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T22:51:06Z","timestamp":1764197466000},"page":"066024","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Enhanced sensory perception and myoelectric control with high channel count implanted sensorimotor systems"],"prefix":"10.1088","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9596-0677","authenticated-orcid":true,"given":"Sedona R","family":"Cady","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9370-0000","authenticated-orcid":true,"given":"Joris","family":"Lambrecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2298-8510","authenticated-orcid":true,"given":"Dustin J","family":"Tyler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2025,12,9]]},"reference":[{"key":"jneae24aebib1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-018-26952-x","type":"journal-article","article-title":"Home use of a neural-connected sensory prosthesis provides the functional and psychosocial experience of having a hand again","volume":"8","author":"Graczyk","year":"2018","journal-title":"Sci. Rep."},{"key":"jneae24aebib2","doi-asserted-by":"publisher","first-page":"362ra142","DOI":"10.1126\/scitranslmed.aaf5187","type":"journal-article","article-title":"The neural basis of perceived intensity in natural and artificial touch","volume":"8","author":"Graczyk","year":"2016","journal-title":"Sci. Transl. Med."},{"key":"jneae24aebib3","doi-asserted-by":"publisher","first-page":"2052","DOI":"10.1523\/JNEUROSCI.1494-21.2021","type":"journal-article","article-title":"Frequency shapes the quality of tactile percepts evoked through electrical stimulation of the nerves","volume":"42","author":"Graczyk","year":"2022","journal-title":"J. Neurosci. Official J. Soc. Neurosci."},{"key":"jneae24aebib4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1126\/scitranslmed.3008669","type":"journal-article","article-title":"A neural interface provides long-term stable natural touch perception","volume":"6","author":"Tan","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"jneae24aebib5","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s12984-021-00808-4","type":"journal-article","article-title":"Discriminability of multiple cutaneous and proprioceptive hand percepts evoked by intraneural stimulation with Utah slanted electrode arrays in human amputees","volume":"18","author":"Page","year":"2021","journal-title":"J. Neuroeng. Rehabil."},{"key":"jneae24aebib6","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1002\/ana.25384","type":"journal-article","article-title":"Six\u2010month assessment of a hand prosthesis with intraneural tactile feedback","volume":"85","author":"Petrini","year":"2019","journal-title":"Ann. Neurol."},{"key":"jneae24aebib7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1126\/scitranslmed.3008933","type":"journal-article","article-title":"An osseointegrated human-machine gateway for long-term sensory feedback and motor control of artificial limbs","volume":"6","author":"Ortiz-Catalan","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"jneae24aebib8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1088\/1741-2560\/12\/2\/026002","type":"journal-article","article-title":"Stability and selectivity of a chronic, multi-contact cuff electrode for sensory stimulation in human amputees","volume":"12","author":"Tan","year":"2015","journal-title":"J. Neural Eng."},{"key":"jneae24aebib9","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.1056\/NEJMoa1917537","type":"journal-article","article-title":"Self-contained neuromusculoskeletal arm prostheses","volume":"382","author":"Ortiz-Catalan","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"jneae24aebib10","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1113\/jphysiol.1978.sp012411","type":"journal-article","article-title":"Tactile sensibility in the human hand: receptive field characteristics of mechanoreceptive units in the glabrous skin area","volume":"281","author":"Johansson","year":"1978","journal-title":"J. Physiol."},{"key":"jneae24aebib11","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/S0361-9230(96)00324-3","type":"journal-article","article-title":"Peripheral afferents with common function cluster in the median nerve and somatotopically innervate the human palm","volume":"42","author":"Ekedahl","year":"1997","journal-title":"Brain Res. Bull."},{"key":"jneae24aebib12","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1016\/j.jhsa.2008.01.007","type":"journal-article","article-title":"An implanted upper-extremity neuroprosthesis using myoelectric control","volume":"33","author":"Kilgore","year":"2008","journal-title":"J. Hand Surg."},{"key":"jneae24aebib13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1088\/1741-2552\/ad56c9","type":"journal-article","article-title":"A distributed, high-channel-count, implanted bidirectional system for restoration of somatosensation and myoelectric control","volume":"21","author":"Lambrecht","year":"2024","journal-title":"J. Neural Eng."},{"key":"jneae24aebib14","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1186\/s12984-025-01613-z","type":"journal-article","article-title":"First-in-human implementation of a bidirectional somatosensory neuroprosthetic system with wireless communication","volume":"22","author":"Cady","year":"2025","journal-title":"J. Neuroeng. Rehabil."},{"key":"jneae24aebib15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1088\/1741-2552\/abc025","type":"journal-article","article-title":"Long-term performance of Utah slanted electrode arrays and intramuscular electromyographic leads implanted chronically in human arm nerves and muscles","volume":"17","author":"George","year":"2020","journal-title":"J. Neural Eng."},{"key":"jneae24aebib16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12984-019-0607-8","type":"journal-article","article-title":"Stable, three degree-of-freedom myoelectric prosthetic control via chronic bipolar intramuscular electrodes: a case study","volume":"16","author":"Dewald","year":"2019","journal-title":"J. Neuroeng. Rehabil."},{"key":"jneae24aebib17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12984-021-00833-3","type":"journal-article","article-title":"Stable, simultaneous and proportional 4-DoF prosthetic hand control via synergy-inspired linear interpolation: a case series","volume":"18","author":"Lukyanenko","year":"2021","journal-title":"J. Neuroeng. Rehabil."},{"key":"jneae24aebib18","doi-asserted-by":"publisher","first-page":"eadf7360","DOI":"10.1126\/scirobotics.adf7360","type":"journal-article","article-title":"A highly integrated bionic hand with neural control and feedback for use in daily life","volume":"8","author":"Ortiz-Catalan","year":"2023","journal-title":"Sci. Robot."},{"key":"jneae24aebib19","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.jneumeth.2014.07.016","type":"journal-article","article-title":"First-in-man demonstration of a fully implanted myoelectric sensors system to control an advanced electromechanical prosthetic hand","volume":"244","author":"Pasquina","year":"2015","journal-title":"J. Neurosci. Methods"},{"key":"jneae24aebib20","doi-asserted-by":"publisher","first-page":"eaaw6306","DOI":"10.1126\/scirobotics.aaw6306","type":"journal-article","article-title":"Long-term implant of intramuscular sensors and nerve transfers for wireless control of robotic arms in above-elbow amputees","volume":"4","author":"Salminger","year":"2019","journal-title":"Sci. Robot."},{"key":"jneae24aebib21","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/accb0c","type":"journal-article","article-title":"Long-term upper-extremity prosthetic control using regenerative peripheral nerve interfaces and implanted EMG electrodes","volume":"20","author":"Vu","year":"2023","journal-title":"J. Neural Eng."},{"key":"jneae24aebib22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1109\/JTEHM.2016.2616123","type":"journal-article","article-title":"A comparison of pattern recognition control and direct control of a multiple degree-of-freedom transradial prosthesis","volume":"4","author":"Kuiken","year":"2016","journal-title":"IEEE J. Transl. Eng. Health Med."},{"key":"jneae24aebib23","doi-asserted-by":"publisher","DOI":"10.3389\/fresc.2024.1345364","type":"journal-article","article-title":"Implications of EMG channel count: enhancing pattern recognition online prosthetic testing","volume":"5","author":"Simon","year":"2024","journal-title":"Front. Rehabil. Sci."},{"key":"jneae24aebib24","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/aabca0","type":"journal-article","article-title":"Influence of nerve cuff channel count and implantation site on the separability of afferent ENG","volume":"15","author":"Silveira","year":"2018","journal-title":"J. Neural Eng."},{"key":"jneae24aebib25","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/abd0ce","type":"journal-article","article-title":"The Argo: a high channel count recording system for neural recording in vivo","volume":"18","author":"Sahasrabuddhe","year":"2021","journal-title":"J. Neural Eng."},{"key":"jneae24aebib26","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/J.JHSB.2004.04.002","type":"journal-article","article-title":"Atlas of hand anatomy and clinical implications. Han-Liang Yu, Robert A. Chase, berish strauch mosby","volume":"29","author":"Comtet","year":"2004","journal-title":"J. Hand Surg."},{"key":"jneae24aebib27","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1109\/TNSRE.2002.806840","type":"journal-article","article-title":"Functionally selective peripheral nerve stimulation with a flat interface nerve electrode","volume":"10","author":"Tyler","year":"2002","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"key":"jneae24aebib28","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1109\/10.83572","type":"journal-article","article-title":"In-line lead connector for use with implanted neuroprosthesis","volume":"38","author":"Letechipia","year":"1991","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"jneae24aebib29","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1111\/ner.12165","type":"journal-article","article-title":"A fully implanted intramuscular bipolar myoelectric signal recording electrode","volume":"17","author":"Memberg","year":"2014","journal-title":"Neuromodulation"},{"key":"jneae24aebib30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1088\/1741-2552\/aa6632","type":"journal-article","article-title":"The design of and chronic tissue response to a composite nerve electrode with patterned stiffness","volume":"14","author":"Freeberg","year":"2017","journal-title":"J. Neural Eng."},{"key":"jneae24aebib31","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1109\/10.204774","type":"journal-article","article-title":"A new strategy for multifunction myoelectric control","volume":"40","author":"Hudgins","year":"1993","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"jneae24aebib32","first-page":"3557","type":"conference-proceedings","article-title":"User-in-the-loop continuous and proportional control of a virtual prosthesis in a posture matching task","volume":"vol 2012","author":"Pulliam","year":"2012"},{"key":"jneae24aebib33","doi-asserted-by":"publisher","first-page":"2283","DOI":"10.1109\/TBME.2022.3141308","type":"journal-article","article-title":"Analysis of neural network based proportional myoelectric hand prosthesis control","volume":"69","author":"Wand","year":"2022","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"jneae24aebib34","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1682\/JRRD.2010.12.0237","type":"journal-article","article-title":"Electromyogram-based neural network control of transhumeral prostheses","volume":"48","author":"Pulliam","year":"2011","journal-title":"J. Rehabil. Res. Dev."},{"key":"jneae24aebib35","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1109\/TNSRE.2011.2178039","type":"journal-article","article-title":"Simultaneous and proportional estimation of hand kinematics from EMG during mirrored movements at multiple degrees-of-freedom","volume":"20","author":"Muceli","year":"2012","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"key":"jneae24aebib36","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1109\/86.481972","type":"journal-article","article-title":"EMG feature evaluation for movement control of upper extremity prostheses","volume":"3","author":"Zardoshti-Kermani","year":"1995","journal-title":"IEEE Trans. Rehabil. Eng."},{"key":"jneae24aebib37","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1016\/0006-8993(80)90804-5","type":"journal-article","article-title":"Spatial properties of the population of mechanoreceptive units in the glabrous skin of the human hand","volume":"184","author":"Johansson","year":"1980","journal-title":"Brain Res."},{"key":"jneae24aebib38","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1113\/jphysiol.1995.sp020622","type":"journal-article","article-title":"Receptive field characteristics of tactile units with myelinated afferents in hairy skin of human subjects","volume":"483","author":"Vallbo","year":"1995","journal-title":"J. Physiol."},{"key":"jneae24aebib39","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s10827-011-0381-5","type":"journal-article","article-title":"Probabilistic modeling of selective stimulation of the human sciatic nerve with a flat interface nerve electrode","volume":"33","author":"Schiefer","year":"2012","journal-title":"J. Comput. Neurosci."},{"key":"jneae24aebib40","doi-asserted-by":"publisher","first-page":"5811","DOI":"10.1109\/IEMBS.2011.6091438","type":"conference-proceedings","article-title":"Optimizing nerve cuff stimulation of targeted regions through use of genetic algorithms","author":"Brill","year":"2011"},{"key":"jneae24aebib41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41551-023-01153-8","type":"journal-article","article-title":"Restoration of sensory feedback from the foot and reduction of phantom limb pain via closed-loop spinal cord stimulation","volume":"8","author":"Nanivadekar","year":"2023","journal-title":"Nat. Biomed. Eng."},{"key":"jneae24aebib42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-017-11306-w","type":"journal-article","article-title":"A somatotopic bidirectional hand prosthesis with transcutaneous electrical nerve stimulation based sensory feedback","volume":"7","author":"D\u2019Anna","year":"2017","journal-title":"Sci. Rep."},{"key":"jneae24aebib43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fnins.2020.00120","type":"journal-article","article-title":"Long-term home-use of sensory-motor-integrated bidirectional bionic prosthetic arms promotes functional, perceptual, and cognitive changes","volume":"14","author":"Schofield","year":"2020","journal-title":"Front. Neurosci."},{"key":"jneae24aebib44","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-47867-1","type":"journal-article","article-title":"Visual inputs and postural manipulations affect the location of somatosensory percepts elicited by electrical stimulation","volume":"9","author":"Christie","year":"2019","journal-title":"Sci. Rep."},{"key":"jneae24aebib45","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12984-017-0320-4","type":"journal-article","article-title":"Restoration of motor control and proprioceptive and cutaneous sensation in humans with prior upper-limb amputation via multiple Utah Slanted Electrode Arrays (USEAs) implanted in residual peripheral arm nerves","volume":"14","author":"Wendelken","year":"2017","journal-title":"J. Neuroeng. Rehabil."},{"key":"jneae24aebib46","doi-asserted-by":"publisher","first-page":"eaax2352","DOI":"10.1126\/scirobotics.aax2352","type":"journal-article","article-title":"Biomimetic sensory feedback through peripheral nerve stimulation improves dexterous use of a bionic hand","volume":"4","author":"George","year":"2019","journal-title":"Sci. Robot."},{"key":"jneae24aebib47","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1088\/1741-2560\/13\/3\/036001","type":"journal-article","article-title":"Restoring motor control and sensory feedback in people with upper extremity amputations using arrays of 96 microelectrodes implanted in the median and ulnar nerves","volume":"13","author":"Davis","year":"2016","journal-title":"J. Neural Eng."},{"key":"jneae24aebib48","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/aabd5d","type":"journal-article","article-title":"Evoked haptic sensations in the hand via non-invasive proximal nerve stimulation","volume":"15","author":"Shin","year":"2018","journal-title":"J. Neural Eng."},{"key":"jneae24aebib49","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1126\/science.adq5978","type":"journal-article","article-title":"Tactile edges and motion via patterned microstimulation of the human somatosensory cortex","volume":"387","author":"Valle","year":"2025","journal-title":"Science"},{"key":"jneae24aebib50","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1109\/TNSRE.2008.918425","type":"journal-article","article-title":"A model of selective activation of the femoral nerve with a flat interface nerve electrode for a lower extremity neuroprosthesis","volume":"16","author":"Schiefer","year":"2008","journal-title":"IEEE Trans. Neural Syst. Rehab. Eng."},{"key":"jneae24aebib51","doi-asserted-by":"publisher","first-page":"1854","DOI":"10.2106\/00004623-199312000-00018","type":"journal-article","article-title":"Peripheral nerve compression","volume":"75","author":"Gelberman","year":"1993","journal-title":"J. Bone Jt. Surg."},{"key":"jneae24aebib52","doi-asserted-by":"publisher","first-page":"366","DOI":"10.3390\/diagnostics10060366","type":"journal-article","article-title":"The branching and innervation pattern of the radial nerve in the forearm: clarifying the literature and understanding variations and their clinical implications","volume":"10","author":"Sawyer","year":"2020","journal-title":"Diagnostics"},{"key":"jneae24aebib53","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1002\/mus.25534","type":"journal-article","article-title":"Quantification of human upper extremity nerves and fascicular anatomy","volume":"56","author":"Brill","year":"2017","journal-title":"Muscle Nerve"},{"key":"jneae24aebib54","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/0006-8993(85)90771-1","type":"journal-article","article-title":"Peripheral axotomy induces neurofilament decrease, atrophy, demyelination and degeneration of root and fasciculus gracilis fibers","volume":"340","author":"Dyck","year":"1985","journal-title":"Brain Res."},{"key":"jneae24aebib55","doi-asserted-by":"publisher","first-page":"2061","DOI":"10.1109\/IEMBS.2010.5626472","type":"conference-proceedings","article-title":"Steering deep brain stimulation fields using a high resolution electrode array","author":"Toader","year":"2010"},{"key":"jneae24aebib56","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1109\/IEMBS.2011.6090244","type":"conference-proceedings","article-title":"Current steering and current focusing with a high-density intracochlear electrode array","author":"Falcone","year":"2011"},{"key":"jneae24aebib57","doi-asserted-by":"publisher","DOI":"10.1177\/1687814019844643","type":"journal-article","article-title":"Multi-modal prosthetic fingertip sensor with proximity, contact, and force localization capabilities","volume":"11","author":"Segil","year":"2019","journal-title":"Adv. Mech. Eng."},{"key":"jneae24aebib58","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1109\/NER52421.2023.10123819","type":"conference-proceedings","article-title":"Distributed tactile sensors for palmar surfaces of prosthetic hands","volume":"vol 00","author":"Truong","year":"2023"},{"key":"jneae24aebib59","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6439\/aaa1d8","type":"journal-article","article-title":"Fabrication and characterization of bending and pressure sensors for a soft prosthetic hand","volume":"28","author":"Rocha","year":"2018","journal-title":"J. Micromech. Microeng."},{"key":"jneae24aebib60","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1109\/TNSRE.2018.2844807","type":"journal-article","article-title":"Design and functional evaluation of a dexterous myoelectric hand prosthesis with biomimetic tactile sensor","volume":"26","author":"Zhang","year":"2018","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"key":"jneae24aebib61","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1109\/TBCAS.2021.3107723","type":"journal-article","article-title":"Embedded electrotactile feedback system for hand prostheses using matrix electrode and electronic skin","volume":"15","author":"Abbass","year":"2021","journal-title":"IEEE Trans. Biomed. Circuits Syst."},{"key":"jneae24aebib62","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1113\/jphysiol.1979.sp012619","type":"journal-article","article-title":"Tactile sensibility in the human hand: relative and absolute densities of four types of mechanoreceptive units in glabrous skin","volume":"286","author":"Johansson","year":"1979","journal-title":"J. Physiol."},{"key":"jneae24aebib63","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.hcl.2008.03.010","type":"journal-article","article-title":"Anatomy and pathomechanics of the thumb","volume":"24","author":"Leversedge","year":"2008","journal-title":"Hand Clin."},{"key":"jneae24aebib64","first-page":"21","author":"Wietlisbach","year":"2019","type":"book"},{"key":"jneae24aebib65","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1109\/EMBC53108.2024.10782980","type":"conference-proceedings","article-title":"From sequential to simultaneous prosthetic control: decoding simultaneous finger movements from individual ground truth EMG patterns","author":"Zbinden","year":"2024"},{"key":"jneae24aebib66","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1109\/TNSRE.2010.2047590","type":"journal-article","article-title":"Continuous detection and decoding of dexterous finger flexions with implantable myoelectric sensors","volume":"18","author":"Baker","year":"2010","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"key":"jneae24aebib67","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/abef3a","type":"journal-article","article-title":"Computational approaches to decode grasping force and velocity level in upper limb amputee from intraneural peripheral signals","volume":"18","author":"Cracchiolo","year":"2021","journal-title":"J. Neural Eng."},{"key":"jneae24aebib68","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1109\/TNSRE.2013.2278411","type":"journal-article","article-title":"Intuitive, online, simultaneous, and proportional myoelectric control over two degrees-of-freedom in upper limb amputees","volume":"22","author":"Jiang","year":"2014","journal-title":"IEEE Trans. Neural Syst. Rehabil."},{"key":"jneae24aebib69","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1109\/TBME.2022.3194104","type":"journal-article","article-title":"Simultaneous and proportional real-time myocontrol of up to three degrees of freedom of the wrist and hand","volume":"70","author":"Nowak","year":"2023","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"jneae24aebib70","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0203835","type":"journal-article","article-title":"Real-time, simultaneous myoelectric control using a convolutional neural network","volume":"13","author":"Ameri","year":"2018","journal-title":"PLoS One"},{"key":"jneae24aebib71","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/1743-0003-9-42","type":"journal-article","article-title":"EMG-based simultaneous and proportional estimation of wrist\/hand kinematics in uni-lateral trans-radial amputees","volume":"9","author":"Jiang","year":"2012","journal-title":"J. Neuroeng. Rehabil."},{"key":"jneae24aebib72","doi-asserted-by":"publisher","first-page":"39","DOI":"10.3389\/fnbot.2020.00039","type":"journal-article","article-title":"Neuromusculoskeletal arm prostheses: personal and social implications of living with an intimately integrated bionic arm","volume":"14","author":"Middleton","year":"2020","journal-title":"Front. Neurorobot."},{"key":"jneae24aebib73","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0277917","type":"journal-article","article-title":"Kinematic analysis of impairments and compensatory motor behavior during prosthetic grasping in below-elbow amputees","volume":"17","author":"Touillet","year":"2022","journal-title":"PLoS One"},{"key":"jneae24aebib74","doi-asserted-by":"publisher","first-page":"2470","DOI":"10.1080\/09638288.2020.1829106","type":"journal-article","article-title":"Dexterity, activity performance, disability, quality of life, and independence in upper limb Veteran prosthesis users: a normative study","volume":"44","author":"Resnik","year":"2022","journal-title":"Disabil. Rehabil."},{"key":"jneae24aebib75","doi-asserted-by":"publisher","first-page":"2057","DOI":"10.1016\/j.apmr.2008.05.016","type":"journal-article","article-title":"Control of a six degree of freedom prosthetic arm after targeted muscle reinnervation surgery","volume":"89","author":"Miller","year":"2008","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"jneae24aebib76","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1186\/s12984-018-0402-y","type":"journal-article","article-title":"Control within a virtual environment is correlated to functional outcomes when using a physical prosthesis","volume":"15","author":"Hargrove","year":"2018","journal-title":"J. Neuroeng. Rehabil."}],"container-title":["Journal of Neural Engineering"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ae24ae","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ae24ae\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ae24ae","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ae24ae\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ae24ae\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ae24ae\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ae24ae\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ae24ae\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T13:37:37Z","timestamp":1765287457000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1741-2552\/ae24ae"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,1]]},"references-count":76,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,12,9]]},"published-print":{"date-parts":[[2025,12,1]]}},"URL":"https:\/\/doi.org\/10.1088\/1741-2552\/ae24ae","relation":{},"ISSN":["1741-2560","1741-2552"],"issn-type":[{"value":"1741-2560","type":"print"},{"value":"1741-2552","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,1]]},"assertion":[{"value":"Enhanced sensory perception and myoelectric control with high channel count implanted sensorimotor systems","name":"article_title","label":"Article Title"},{"value":"Journal of Neural Engineering","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2025 The Author(s). Published by IOP Publishing Ltd","name":"copyright_information","label":"Copyright Information"},{"value":"2025-05-14","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2025-11-26","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2025-12-09","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}