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Testing included the comparison of porosity, swelling, mechanical integrity, cellular infiltration, and mineralization potential between all types of cryogels. The addition of bone char to CG cryogels produced scaffolds with appropriate porosity and interconnectivity. Additionally, the bone char cryogels exhibited an adequate swelling potential, suitable mechanical properties, excellent cell attachment, and increased mineralization. These properties support this cryogel for such an application in tissue engineering.<\/jats:p>","DOI":"10.1088\/1748-605x\/aa5d76","type":"journal-article","created":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T09:15:14Z","timestamp":1485940514000},"page":"025005","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":31,"title":["The calcification potential of cryogel scaffolds incorporated with various forms of hydroxyapatite for bone regeneration"],"prefix":"10.1088","volume":"12","author":[{"given":"Katherine R","family":"Hixon","sequence":"first","affiliation":[{"name":"Saint Louis University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher T","family":"Eberlin","sequence":"additional","affiliation":[{"name":"Saint Louis University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy","family":"Lu","sequence":"additional","affiliation":[{"name":"Saint Louis University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sydney M","family":"Neal","sequence":"additional","affiliation":[{"name":"Saint Louis University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha D","family":"Case","sequence":"additional","affiliation":[{"name":"Saint Louis University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah H","family":"McBride-Gagyi","sequence":"additional","affiliation":[{"name":"Saint Louis University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott A","family":"Sell","sequence":"additional","affiliation":[{"name":"Saint Louis University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2017,3,7]]},"reference":[{"key":"bmmaa5d76bib1","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1038\/nrrheum.2014.164","type":"journal-article","article-title":"Fracture healing: mechanisms and interventions","volume":"11","author":"Einhorn","year":"2015","journal-title":"Nat. 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