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Mater."],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Antimicrobial peptides (AMPs) are considered as novel potential alternatives to antibiotics against increasing number of multi drug resistant (MDR) pathogens. Although AMPs have shown strong antimicrobial activity against gram-negative or gram-positive microorganisms, AMP conjugated biomaterials that are effective against MDR microorganisms are yet to be developed. Herein, the potential use of (RWRWRWRW)-NH2 (AMP-1) and KRFRIRVRV-NH2 (AMP-2) peptide conjugated electrospun polylactic\u2013co-glycolic-acid (PLGA) nanofibers (NFs) fabricated and their antimicrobial effect by themselves and in their dual combination (1:1) were evaluated on\n                    <jats:italic>P. aeruginosa<\/jats:italic>\n                    and methicillin-resistant\n                    <jats:italic>S. aureus<\/jats:italic>\n                    (MRSA). Those AMP conjugated NFs did not inhibit proliferation of keratinocytes. These results suggest that AMP conjugated NF, which has multiple biological activities, would be a promising candidate as a wound dressing material.\n                  <\/jats:p>","DOI":"10.1088\/1748-605x\/abb722","type":"journal-article","created":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T18:32:00Z","timestamp":1599762720000},"page":"015020","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["Antibacterial activity of antimicrobial peptide-conjugated nanofibrous membranes"],"prefix":"10.1088","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0895-4768","authenticated-orcid":false,"given":"G\u00fcnnur","family":"Onak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9762-2265","authenticated-orcid":false,"given":"Utku K\u00fcr\u015fat","family":"Ercan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4175-4402","authenticated-orcid":false,"given":"Ozan","family":"Karaman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2020,12,11]]},"reference":[{"key":"bmmabb722bib1","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1089\/wound.2015.0635","type":"journal-article","article-title":"Challenges in the treatment of chronic wounds","volume":"4","author":"Frykberg","year":"2015","journal-title":"Adv. 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