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This approach significantly enhances the dynamic responsiveness of the start-stop transition during printing, thereby reducing harmful errors by up to 93%. Leveraging this enhanced material, we have efficiently fabricated arrays of multi-branched vascular scaffolds that exhibit exceptional morphological fidelity and possess elastic moduli that faithfully approximate the physiological modulus spectrum of native blood vessels, ranging from 2.5 to 45 MPa. The methodology we propose for the compatibilization and modification of elastomeric materials addresses the challenge of real-time precision control, representing a significant advancement in the domain of melt polymer 3D printing. This innovation holds considerable promise for the creation of detailed multi-branch vascular scaffolds and other sophisticated organotypic structures critical to advancing tissue engineering and regenerative medicine.<\/jats:p>","DOI":"10.1088\/1748-605x\/ad407c","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T22:30:18Z","timestamp":1713479418000},"page":"035042","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["High-precision 3D printing of multi-branch vascular scaffold with plasticized PLCL thermoplastic elastomer"],"prefix":"10.1088","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3032-7089","authenticated-orcid":true,"given":"Yunda","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3321-4438","authenticated-orcid":true,"given":"Heran","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuheng","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zewei","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihua","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiongfei","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2024,4,30]]},"reference":[{"key":"bmmad407cbib1","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1126\/science.8493529","article-title":"Tissue engineering","volume":"260","author":"Langer","year":"1993","journal-title":"Science"},{"key":"bmmad407cbib2","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1038\/nmat1421","article-title":"Porous scaffold design for tissue engineering","volume":"4","author":"Hollister","year":"2005","journal-title":"Nat. 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