{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T20:51:00Z","timestamp":1793911860715,"version":"4.8.0"},"reference-count":110,"publisher":"IOP Publishing","issue":"5","license":[{"start":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T00:00:00Z","timestamp":1721001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T00:00:00Z","timestamp":1721001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Biomed. Mater."],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study was designed to deposit nanodiamonds (NDs) on 3D-printed poly-\n                    <jats:italic>\u03f5<\/jats:italic>\n                    -caprolactone (PCL) scaffolds and evaluate their effect on the surface topography, hydrophilicity, degradation, and\n                    <jats:italic>in-vitro<\/jats:italic>\n                    cell adhesion compared to untreated PCL scaffolds. The PCL scaffold specimens were 3D-printed by fused deposition modeling (FDM) technique with specific porosity parameters. The 3D-printed specimens\u2019 surfaces were modified by NDs deposition followed by oxygen plasma post-treatment using a plasma focus device and a non-thermal atmospheric plasma jet, respectively. Specimens were evaluated through morphological characterization by field emission scanning electron microscope (FESEM), microstructure characterization by Raman spectroscopy, chemical characterization by Fourier transform infrared (FTIR) spectroscopy, hydrophilicity degree by contact angle and water uptake measurements, and\n                    <jats:italic>in-vitro<\/jats:italic>\n                    degradation measurements (\n                    <jats:italic>n<\/jats:italic>\n                    = 6). In addition,\n                    <jats:italic>in-vitro<\/jats:italic>\n                    bone marrow mesenchymal stem cells adhesion was evaluated quantitatively by confocal microscopy and qualitatively by FESEM at different time intervals after cell seeding (\n                    <jats:italic>n<\/jats:italic>\n                    = 6). The statistical significance level was set at\n                    <jats:italic>p<\/jats:italic>\n                    \u2a7d 0.05. The FESEM micrographs, the Raman, and FTIR spectra confirmed the successful surface deposition of NDs on scaffold specimens. The NDs treated specimens showed nano-scale features distributed homogeneously across the surface compared to the untreated ones. Also, the NDs treated specimens revealed a statistically significant smaller contact angle (17.45 \u00b1 1.34 degrees), higher water uptake percentage after 24 h immersion in phosphate buffer saline (PBS) (21.56% \u00b1 1.73), and higher degradation rate after six months of immersion in PBS (43.92 \u00b1 0.77%). Moreover, enhanced cell adhesion at all different time intervals was observed in NDs treated specimens with higher nuclei area fraction percentage (69.87 \u00b1 3.97%) compared to the untreated specimens (11.46 \u00b1 1.34%). Surface deposition of NDs with oxygen-containing functional groups on 3D-printed PCL scaffolds increased their hydrophilicity and degradation rate with significant enhancement of the\n                    <jats:italic>in-vitro<\/jats:italic>\n                    cell adhesion compared to untreated PCL scaffolds.\n                  <\/jats:p>","DOI":"10.1088\/1748-605x\/ad5bac","type":"journal-article","created":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T18:42:46Z","timestamp":1719340966000},"page":"055016","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["Effect of nanodiamonds surface deposition on hydrophilicity, bulk degradation and in-vitro cell adhesion of 3D-printed polycaprolactone scaffolds for bone tissue engineering"],"prefix":"10.1088","volume":"19","author":[{"given":"Hadiah A","family":"ElBakry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3002-7429","authenticated-orcid":true,"given":"Mohamed M","family":"Ammar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taheya A","family":"Moussa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2024,7,15]]},"reference":[{"key":"bmmad5bacbib1","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.biomaterials.2017.06.005","article-title":"Biomaterials polymer structure-property requirements for stereolithographic 3D printing of soft tissue engineering scaffolds","volume":"140","author":"Mondschein","year":"2017","journal-title":"Biomaterials"},{"key":"bmmad5bacbib2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/jfb9030050","article-title":"Tailoring the interface of biomaterials to design effective scaffolds","volume":"9","author":"Parisi","year":"2018","journal-title":"J. Funct. Biomater."},{"key":"bmmad5bacbib3","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1007\/s12033-018-0084-5","article-title":"PCL\u2013based composite scaffold matrices for tissue engineering applications","volume":"60","author":"Siddiqui","year":"2018","journal-title":"Mol. Biotechnol."},{"key":"bmmad5bacbib4","doi-asserted-by":"publisher","first-page":"218","DOI":"10.3390\/bioengineering10020218","article-title":"Polymeric materials, advances and applications in tissue engineering: a review","volume":"10","author":"Socci","year":"2023","journal-title":"Bioengineering"},{"key":"bmmad5bacbib5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms20020435","article-title":"Current trends in fabrication of biomaterials for bone and cartilage regeneration: materials modifications and biophysical stimulations","volume":"20","author":"Przekora","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"bmmad5bacbib6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2019\/3429527","article-title":"Scaffold techniques and designs in tissue engineering functions and purposes: a review","volume":"3429527","author":"Eltom","year":"2019","journal-title":"Adv. Mater. Sci. Eng."},{"key":"bmmad5bacbib7","doi-asserted-by":"publisher","first-page":"11238","DOI":"10.1021\/acs.chemrev.0c01200","article-title":"Fabrication of biomedical scaffolds using biodegradable polymers","volume":"121","author":"Kirillova","year":"2022","journal-title":"Chem. Rev."},{"key":"bmmad5bacbib8","doi-asserted-by":"publisher","first-page":"241","DOI":"10.2174\/1874070701812010241","article-title":"A review of three-dimensional printing for biomedical and tissue engineering applications","volume":"12","author":"Devi","year":"2018","journal-title":"Open Biotechnol. J."},{"key":"bmmad5bacbib9","volume":"vol 29","author":"Malikmammadov","year":"2018"},{"key":"bmmad5bacbib10","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.jobcr.2019.10.003","article-title":"Polycaprolactone as biomaterial for bone scaffolds: review of literature","volume":"10","author":"Dwivedi","year":"2020","journal-title":"J. Oral Biol. Craniofac. Res."},{"key":"bmmad5bacbib11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-020-78977-w","article-title":"Fabrication and characterization of mechanically competent 3D printed polycaprolactone\u2013reduced graphene oxide scaffolds","volume":"10","author":"Seyedsalehi","year":"2020","journal-title":"Sci. Rep."},{"key":"bmmad5bacbib12","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1208\/s12249-022-02419-1","article-title":"Biomaterials for tissue engineering applications and current updates in the field: a comprehensive review","volume":"23","author":"Eldeeb","year":"2022","journal-title":"AAPS Pharm. Sci. Tech."},{"key":"bmmad5bacbib13","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.msec.2020.111433","article-title":"3D printing of silk microparticle reinforced polycaprolactone scaffolds for tissue engineering applications","volume":"118","author":"Vyas","year":"2021","journal-title":"Mater. Sci. Eng. C"},{"key":"bmmad5bacbib14","author":"Fabbri","year":"2017"},{"key":"bmmad5bacbib15","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1002\/ppap.201000153","article-title":"Plasma surface modification of biodegradable polymers: a review","volume":"8","author":"Morent","year":"2011","journal-title":"Plasma Process. Polym."},{"key":"bmmad5bacbib16","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.ejpb.2013.06.012","article-title":"Plasma treatment for improving cell biocompatibility of a biodegradable polymer scaffold for vascular graft applications","volume":"85","author":"Valence","year":"2013","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"bmmad5bacbib17","doi-asserted-by":"publisher","first-page":"254","DOI":"10.3762\/bjnano.6.24","article-title":"Oxygen-plasma-modified biomimetic nanofibrous scaffolds for enhanced compatibility of cardiovascular implants","volume":"6","author":"Pappa","year":"2015","journal-title":"Eilstein J. Nanotechnol."},{"key":"bmmad5bacbib18","doi-asserted-by":"publisher","DOI":"10.1088\/1758-5082\/2\/1\/014109","article-title":"Accelerated differentiation of osteoblast cells on polycaprolactone scaffolds driven by a combined effect of protein coating and plasma modification","volume":"2","author":"Yildirim","year":"2010","journal-title":"Biofabrication."},{"key":"bmmad5bacbib19","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1007\/s11090-015-9667-0","article-title":"Plasma processing of scaffolds for tissue engineering and regenerative medicine","volume":"36","author":"Intranuovo","year":"2015","journal-title":"Plasma Chem."},{"key":"bmmad5bacbib20","doi-asserted-by":"publisher","first-page":"201","DOI":"10.5772\/62007","article-title":"Non-thermal plasma technology for the improvement of scaffolds for tissue engineering and regenerative medicine\u2014a review","volume":"62007","author":"Cools","year":"2016","journal-title":"Plasma Sci. Technol."},{"key":"bmmad5bacbib21","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1089\/ten.tec.2013.0701","article-title":"A surface-modified poly(e-caprolactone) scaffold comprising variable nanosized surface-roughness using a plasma treatment","volume":"20","author":"Jeon","year":"2014","journal-title":"Tissue Eng."},{"key":"bmmad5bacbib22","doi-asserted-by":"publisher","first-page":"11","DOI":"10.5923\/j.nn.20180801.03","article-title":"Recent progress in biomedical applications of nanodiamonds","volume":"8","author":"Martel-Estrada","year":"2018","journal-title":"Nanosci. Nanotechnol."},{"key":"bmmad5bacbib23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/smll.201704263","article-title":"Nanodiamonds and their applications in cells","volume":"14","author":"Chipaux","year":"2018","journal-title":"Adv. Sci. News"},{"key":"bmmad5bacbib24","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1038\/nnano.2011.209","article-title":"The properties and applications of nanodiamonds","volume":"7","author":"Mochalin","year":"2014","journal-title":"Nat. Nanotechnol."},{"key":"bmmad5bacbib25","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.jddst.2023.105130","article-title":"Nanodiamonds for tissue engineering and regeneration","volume":"90","author":"Moein","year":"2023","journal-title":"J. Drug Deliv. Sci. Tech."},{"key":"bmmad5bacbib26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jpha.2018.11.003","article-title":"Nanodiamonds with powerful ability for drug delivery and biomedical applications: recent updates on in vivo study and patents","volume":"9","author":"Yang","year":"2019","journal-title":"J. Pharm. Anal."},{"key":"bmmad5bacbib27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/nano11010153","article-title":"Surface modification of fluorescent nanodiamonds for biological applications","volume":"11","author":"Jung","year":"2021","journal-title":"Nanomaterials"},{"key":"bmmad5bacbib28","doi-asserted-by":"publisher","first-page":"3524","DOI":"10.1166\/jnn.2009.NS26","article-title":"Nanodiamond as promising material for bone tissue engineering","volume":"9","author":"Grausova","year":"2009","journal-title":"J. Nanosci. Nanotechnol."},{"key":"bmmad5bacbib29","doi-asserted-by":"publisher","first-page":"1783","DOI":"10.1089\/ten.tea.2012.0336","article-title":"Biological effects of functionalizing copolymer scaffolds with nanodiamond particles","volume":"19","author":"Xing","year":"2013","journal-title":"Tissue Eng."},{"key":"bmmad5bacbib30","first-page":"1","article-title":"Using cold plasma as a surface treatment with PEEK dental implant: a case series","volume":"5","author":"Dohiem","year":"2019","journal-title":"Futur. Dent. J."},{"key":"bmmad5bacbib31","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.diamond.2010.01.002","article-title":"Termination of diamond surfaces with hydrogen, oxygen and fluorine using a small, simple plasma gun","volume":"19","author":"Salvadori","year":"2010","journal-title":"Diam. Relat. Mater."},{"key":"bmmad5bacbib32","doi-asserted-by":"publisher","first-page":"2433","DOI":"10.1016\/j.biomaterials.2008.01.036","article-title":"The role of oxygen termination of nanocrystalline diamond on immobilisation of BMP-2 and subsequent bone formation","volume":"29","author":"Kloss","year":"2008","journal-title":"Biomaterials"},{"key":"bmmad5bacbib33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-017-07361-y","article-title":"Surface functionalisation of nanodiamonds for human neural stem cell adhesion and proliferation","volume":"7","author":"Taylor","year":"2017","journal-title":"Sci. Rep."},{"key":"bmmad5bacbib34","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.msec.2020.111525","article-title":"Fabrication of 3D printed antimicrobial polycaprolactone scaffolds for tissue engineering applications","volume":"118","author":"Radhakrishnan","year":"2021","journal-title":"Mater. Sci. Eng. C"},{"key":"bmmad5bacbib35","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1109\/TPS.2004.826031","article-title":"Shadowgraphic studies of DLC film deposition process in dense plasma focus device","volume":"32","author":"Soh","year":"2004","journal-title":"IEEE Trans. Plasma Sci."},{"key":"bmmad5bacbib36","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1088\/0022-3727\/42\/17\/175001","article-title":"Magnetic CoPt nanoparticles deposition using plasma focus device","volume":"8","author":"Pan","year":"2009","journal-title":"Plasma Sci. Nucl. Fusion J."},{"key":"bmmad5bacbib37","doi-asserted-by":"publisher","first-page":"2539","DOI":"10.1109\/TPS.2015.2445055","article-title":"Dense plasma focus device based high growth rate room temperature synthesis of nanostructured zinc oxide thin films","volume":"43","author":"Tan","year":"2015","journal-title":"IEEE Trans. Plasma Sci."},{"key":"bmmad5bacbib38","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1063\/1.5142198","article-title":"Near- and far-field Raman spectroscopic studies of nanodiamond composite films deposited by coaxial arc plasma","volume":"116","author":"Ali","year":"2020","journal-title":"Appl. Phys. Lett."},{"key":"bmmad5bacbib39","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1007\/s10582-006-0205-4","article-title":"Deposition of nanolayers by means of dense plasma focus","volume":"56","author":"Chernyshova","year":"2006","journal-title":"Czech. J. Phys."},{"key":"bmmad5bacbib40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1063\/1.4997877","article-title":"Ti film deposition process of a plasma focus: study by an experimental design","volume":"7","author":"Inestrosa-Izurieta","year":"2017","journal-title":"AIP Adv."},{"key":"bmmad5bacbib41","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1088\/0963-0252\/16\/2\/006","article-title":"Optimization of a plasma focus device as an electron beam source for thin film","volume":"250","author":"Zhang","year":"2007","journal-title":"Plasma Sources Sci. Technol."},{"key":"bmmad5bacbib42","doi-asserted-by":"publisher","first-page":"11517","DOI":"10.1039\/c1cp20424f","article-title":"Surface properties of hydrogenated nanodiamonds: a chemical investigation","volume":"13","author":"Girard","year":"2011","journal-title":"Phys. Chem. Chem. Phys."},{"key":"bmmad5bacbib43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/nano10050948","article-title":"High nanodiamond content-PCL composite for tissue engineering scaffolds","volume":"10","author":"Fox","year":"2020","journal-title":"Nanomaterials"},{"key":"bmmad5bacbib44","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/j.colsurfa.2018.12.023","article-title":"Surface modification and disaggregation of detonation nanodiamond particles with biodegradable polyurethane","volume":"563","author":"Hu","year":"2019","journal-title":"Colloids Surf. A"},{"key":"bmmad5bacbib45","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ma13030512","article-title":"3D printing of polycaprolactone\u2014polyaniline electroactive scaffolds for bone tissue engineering","volume":"13","author":"Wibowo","year":"2020","journal-title":"Materials"},{"key":"bmmad5bacbib46","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1002\/jbm.a.34398","article-title":"Plasma treatment of electrospun PCL random nanofiber meshes (NFMs) for biological property improvement","volume":"101","author":"Yan","year":"2012","journal-title":"Biomed. Mater. Res. J."},{"key":"bmmad5bacbib47","doi-asserted-by":"publisher","first-page":"2396","DOI":"10.1002\/pen.23193","article-title":"Morphology, wettability, and mechanical properties of polycaprolactone\/hydroxyapatite composite scaffolds with interconnected pore structures fabricated by a mini-deposition system","volume":"52","author":"Jiang","year":"2012","journal-title":"Polym. Eng. Sci."},{"key":"bmmad5bacbib48","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1021\/acsmacrolett.8b00424","article-title":"Hydrolytic degradation and erosion of polyester biomaterials","volume":"7","author":"Woodard","year":"2018","journal-title":"Am. Chem. Soc."},{"key":"bmmad5bacbib49","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1016\/j.compscitech.2012.01.023","article-title":"Preparation and characterization of polycaprolactone\/forsterite nanocomposite porous scaffolds designed for bone tissue regeneration","volume":"72","author":"Diba","year":"2012","journal-title":"Compos. Sci. Technol."},{"key":"bmmad5bacbib50","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10856-019-6244-8","article-title":"Biodegradable silver-loaded polycation modified nanodiamonds\/polyurethane scaffold with improved antibacterial and mechanical properties for cartilage tissue repairing","volume":"30","author":"Wang","year":"2019","journal-title":"J. Mater. Sci., Mater. Med."},{"key":"bmmad5bacbib51","doi-asserted-by":"publisher","first-page":"2276","DOI":"10.1038\/nprot.2007.319","article-title":"Changing medium and passaging cell lines","volume":"2","author":"Masters","year":"2007","journal-title":"Nat. Protocols"},{"key":"bmmad5bacbib52","doi-asserted-by":"publisher","first-page":"2745","DOI":"10.2147\/IJN.S44885","article-title":"In vitro proliferation and osteogenic differentiation of mesenchymal stem cells on nanoporous alumina","volume":"8","author":"Song","year":"2013","journal-title":"Int. J. Nanomed."},{"key":"bmmad5bacbib53","doi-asserted-by":"publisher","first-page":"4495","DOI":"10.1016\/j.actbio.2010.06.024","article-title":"Three-dimensional nanocomposite scaffolds fabricated via selective laser sintering for bone tissue engineering","volume":"6","author":"Duan","year":"2010","journal-title":"Acta Biomater."},{"key":"bmmad5bacbib54","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/j.cej.2019.04.017","article-title":"Alkaline phosphatase enzyme-induced biomineralization of chitosan scaffolds with enhanced osteogenesis for bone tissue engineering","volume":"371","author":"Li","year":"2019","journal-title":"Chem. Eng. J."},{"key":"bmmad5bacbib55","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1089\/3dp.2018.0056","article-title":"Hybrid additive manufacturing system for zonal plasmatreated scaffolds","volume":"5","author":"Liu","year":"2018","journal-title":"3D Print. Addit. Manuf."},{"key":"bmmad5bacbib56","doi-asserted-by":"publisher","DOI":"10.1088\/2631-7990\/acbd6c","article-title":"Embedding aligned nanofibrous architectures within 3D-printed polycaprolactone scaffolds for directed cellular infiltration and tissue regeneration","volume":"5","author":"Meng","year":"2023","journal-title":"Int. J. Extrem. Manuf."},{"key":"bmmad5bacbib57","doi-asserted-by":"publisher","first-page":"992","DOI":"10.3390\/ma9120992","article-title":"Enhancing the hydrophilicity and cell attachment of 3D printed PCL\/graphene scaffolds for bone tissue engineering","volume":"9","author":"Wang","year":"2016","journal-title":"Materials"},{"key":"bmmad5bacbib58","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.molstruc.2020.128135","article-title":"A 2D-Raman correlation spectroscopy study of the interaction of the polymer nanocomposites with carbon nanotubes and human osteoblast-like cells interface","volume":"12","author":"Ko","year":"2020","journal-title":"J. Mol. Struct."},{"key":"bmmad5bacbib59","doi-asserted-by":"publisher","first-page":"1","DOI":"10.29252\/ijop.13.1.3","article-title":"Laser micro-Raman spectroscopy of CVD nanocrystalline diamond thin film","volume":"13","author":"Motahari","year":"2019","journal-title":"Int. J. Opt. Photon."},{"key":"bmmad5bacbib60","doi-asserted-by":"publisher","first-page":"5338","DOI":"10.1039\/c8ra06652c","article-title":"Modification of 3D printed PCL scaffolds by PVAc and HA to enhance cytocompatibility and osteogenesis","volume":"9","author":"Ma","year":"2019","journal-title":"R. Soc. Chem. J."},{"key":"bmmad5bacbib61","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1016\/j.biomaterials.2005.09.019","article-title":"The in vivo degradation, absorption and excretion of PCL-based implant","volume":"27","author":"Sun","year":"2006","journal-title":"Biomaterials."},{"key":"bmmad5bacbib62","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1080\/17452750802547338","article-title":"Fabrication and plasma treatment of 3D polycaprolactane tissue scaffolds for enhanced cellular function","volume":"3","author":"Sun","year":"2008","journal-title":"Virtual Phys. Prototyp."},{"key":"bmmad5bacbib63","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40824-018-0126-x","article-title":"Fabrication and optimization of nanodiamonds-composited poly (\u03f5-caprolactone) fibrous matrices for potential regeneration of hard tissues","volume":"22","author":"Ahn","year":"2018","journal-title":"Biomaterials."},{"key":"bmmad5bacbib64","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.jare.2019.03.011","article-title":"Carbon based nanomaterials for tissue engineering of bone: building new bone on small black scaffolds: a review","volume":"18","author":"Eivazzadeh-keihan","year":"2019","journal-title":"J. Adv. Res."},{"key":"bmmad5bacbib65","doi-asserted-by":"publisher","first-page":"6629","DOI":"10.1039\/C7TB00723J","article-title":"Functionalization of bone implants with nanodiamond particles and angiopoietin-1 to improve vascularization and bone regeneration","volume":"5","author":"Wu","year":"2017","journal-title":"J. Mater. Chem. B"},{"key":"bmmad5bacbib66","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.201600427","article-title":"A copolymer scaffold functionalized with nanodiamond particles enhances osteogenic metabolic activity and bone regeneration","volume":"17","author":"Yassin","year":"2017","journal-title":"Macromol. Biosci. J."},{"key":"bmmad5bacbib67","doi-asserted-by":"publisher","first-page":"1611","DOI":"10.1016\/j.apsusc.2006.02.047","article-title":"Nano-structured Fe thin film deposition using plasma focus device","volume":"253","author":"Rawat","year":"2009","journal-title":"Appl. Surf. Sci."},{"key":"bmmad5bacbib68","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1142\/9789814504898_0012","article-title":"Nanostructure iron-silicon thin film deposition using plasma focus device","volume":"8","author":"Kotb","year":"2013","journal-title":"Mod. Trends Phys. Res."},{"key":"bmmad5bacbib69","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/ncomms3618","article-title":"Formation of nanodiamonds at near-ambient conditions via microplasma dissociation of ethanol vapour","volume":"4","author":"Kumar","year":"2014","journal-title":"Nat. Commun."},{"key":"bmmad5bacbib70","doi-asserted-by":"publisher","first-page":"1689","DOI":"10.1089\/ten.tea.2013.0569","article-title":"Surface plasma treatment of poly(caprolactone) micro, nano, and multiscale fibrous scaffolds for enhanced osteoconductivity","volume":"20","author":"Sankar","year":"2014","journal-title":"Tissue Eng."},{"key":"bmmad5bacbib71","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1088\/1361-6463\/aa76f5","article-title":"Modern plasma physics and chemistry","volume":"1","author":"Hatakeyama","year":"2017","journal-title":"J. Phys. D: Appl. Phys."},{"key":"bmmad5bacbib72","doi-asserted-by":"publisher","first-page":"11635","DOI":"10.1021\/ja063303n","article-title":"Control of sp2\/sp3 carbon ratio and surface chemistry of nanodiamond powders by selective oxidation in air","volume":"128","author":"Osswald","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"bmmad5bacbib73","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1021\/jp063383h","article-title":"A theoretical study of the energetic stability and geometry of hydrogen- and oxygen-terminated diamond (100) surfaces","volume":"111","author":"Petrini","year":"2007","journal-title":"J. Phys. Chem. C"},{"key":"bmmad5bacbib74","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jpha.2019.09.003","article-title":"Nanodiamonds with powerful ability for drug delivery and biomedical applications: recent updates on in vivo study and patents","volume":"10","author":"Chauhan","year":"2020","journal-title":"J. Pharm. Anal."},{"key":"bmmad5bacbib75","doi-asserted-by":"publisher","DOI":"10.1016\/j.matdes.2023.112179","article-title":"Recent advances in the structure and biomedical applications of nanodiamonds and their future perspectives","volume":"233","author":"Pan","year":"2023","journal-title":"Mater. Des."},{"key":"bmmad5bacbib76","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.dental.2016.11.011","article-title":"Non-thermal atmospheric pressure plasma functionalized dental implant for enhancement of bacterial resistance and osseointegration","volume":"33","author":"Lee","year":"2017","journal-title":"Dent. Mater."},{"key":"bmmad5bacbib77","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1002\/ppap.201500104","article-title":"He\/O2 atmospheric pressure plasma jet treatments of PCL scaffolds for tissue engineering and regenerative medicine","volume":"12","author":"Trizio","year":"2015","journal-title":"Plasma Process. Polym."},{"key":"bmmad5bacbib78","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1002\/ppap.201300104","article-title":"Carboxyl surface functionalization of poly (L-lactic acid) electrospun nanofibers through atmospheric non-thermal plasma affects fibroblast morphology","volume":"11","author":"Dolci","year":"2014","journal-title":"Plasma Process. Polym."},{"key":"bmmad5bacbib79","doi-asserted-by":"publisher","first-page":"7654","DOI":"10.1166\/jnn.2014.9414","article-title":"Air atmospheric pressure plasma jet pretreatment for drop-wise loading of dexamethasone on hydroxyapatite scaffold for increase of osteoblast attachment","volume":"14","author":"Lee","year":"2014","journal-title":"J. Nanosci. Nanotechnol."},{"key":"bmmad5bacbib80","doi-asserted-by":"publisher","first-page":"7938","DOI":"10.1016\/j.jmrt.2023.05.076","article-title":"Surface modifications of scaffolds for bone regeneration","volume":"24","author":"Teimouri","year":"2023","journal-title":"J. Mater. Res. Technol."},{"key":"bmmad5bacbib81","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/j.diamond.2006.108394","article-title":"Large-area and low-temperature nanodiamond coating by microwave plasma chemical vapor deposition","volume":"16","author":"Tsugawa","year":"2006","journal-title":"New Diam. Front. Carbon Technol."},{"key":"bmmad5bacbib82","doi-asserted-by":"publisher","first-page":"19647","DOI":"10.1039\/C6RA02486F","article-title":"Antimicrobial electrospun poly(caprolactone) scaffolds for gingival fibroblast growth","volume":"6","author":"Baranowska-korczyc","year":"2016","journal-title":"R. Soc. Chem. Adv."},{"key":"bmmad5bacbib83","doi-asserted-by":"publisher","first-page":"8573","DOI":"10.1021\/acs.jpcc.8b00354","article-title":"Effect of surface passivation on nanodiamond crystallinity","volume":"122","author":"Beck","year":"2018","journal-title":"J. Phys. Chem. C"},{"key":"bmmad5bacbib84","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.mssp.2017.10.002","article-title":"Impact of carrier gas flow rate on the synthesis of nanodiamonds via microplasma technique","volume":"74","author":"Iqbal","year":"2018","journal-title":"Mater. Sci. Semicond. Process."},{"key":"bmmad5bacbib85","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/2193-8865-3-27","article-title":"Effect of catalyst on growth of diamond by plasma-enhanced chemical vapor deposition","volume":"3","author":"Zare","year":"2013","journal-title":"J. Nanostruct. Chem."},{"key":"bmmad5bacbib86","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.diamond.2022.108820","article-title":"Preparation and characterization of diamond-like carbon films on various substrates by PECVD system","volume":"3","author":"Vaghri","year":"2012","journal-title":"Stud. Univ. Babes-Bolyai Chem."},{"key":"bmmad5bacbib87","doi-asserted-by":"publisher","first-page":"187","DOI":"10.4028\/www.scientific.net\/AMM.79.187","article-title":"Synthesis and characterization of nanocrystalline diamond films deposited by microwave plasma chemical vapour deposition","volume":"79","author":"Zhou","year":"2011","journal-title":"Appl. Mech. Mater."},{"key":"bmmad5bacbib88","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.diamond.2011.10.023","article-title":"Wettability of plasma-treated nanocrystalline diamond films","volume":"24","author":"Yang Teii","year":"2012","journal-title":"Diam. Relat. Mater"},{"key":"bmmad5bacbib89","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.eurpolymj.2015.08.025","article-title":"Non-mulberry silk fibroin grafted PCL nanofibrous scaffold: promising ECM for bone tissue engineering","volume":"15","author":"Kundu","year":"2015","journal-title":"Eur. Polym. J."},{"key":"bmmad5bacbib90","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fmats.2020.528590","article-title":"Surface functionalization of three polycaprolactone-bioactive glass scaffolds by grafting GelMA under UV irradiation","volume":"7","author":"Ghorbani","year":"2020","journal-title":"J. Front. Mater."},{"key":"bmmad5bacbib91","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1002\/mame.201400387","article-title":"Reinforced degradable biocomposite by homogenously distributed functionalized nanodiamond particles","volume":"300","author":"Sun","year":"2015","journal-title":"Macromol. Mater. Eng."},{"key":"bmmad5bacbib92","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/jfb7030027","article-title":"Synthesis and characterization of nanodiamond reinforced chitosan for bone tissue engineering","volume":"7","author":"Sun","year":"2016","journal-title":"J. Funct. Biomater."},{"key":"bmmad5bacbib93","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1117\/12.2252892","article-title":"Nanodiamond preparation and surface characterization for biological applications","volume":"10079","author":"Woodhams","year":"2017","journal-title":"Proc. SPIE"},{"key":"bmmad5bacbib94","doi-asserted-by":"publisher","first-page":"8743","DOI":"10.1039\/C5RA19669H","article-title":"Biodegradable polyurethane acrylate\/HEMAgrafted nanodiamond composites with bone regenerative potential applications: structure, mechanical properties and biocompatibility","volume":"6","author":"Alishiri","year":"2016","journal-title":"R. Soc. Chem. Adv."},{"key":"bmmad5bacbib95","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1002\/jbm.a.32227","article-title":"Orthopedic nano diamond coatings: control of surface properties and their impact on osteoblast adhesion and proliferation","volume":"91","author":"Yang","year":"2009","journal-title":"J. Biomed. Mater. Res. A"},{"key":"bmmad5bacbib96","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.matchemphys.2017.03.051","article-title":"Surface modification of PCL-diopside fibrous membrane via gelatin immobilization for bone tissue engineering","volume":"194","author":"Hosseini","year":"2017","journal-title":"Mater. Chem. Phys."},{"key":"bmmad5bacbib97","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1002\/pi.2195","article-title":"Comparison of the degradation of polycaprolactone and polycaprolactone\u2014(\u03b2-tricalcium phosphate) scaffolds in alkaline medium","volume":"56","author":"Lam","year":"2007","journal-title":"Polym. Int."},{"key":"bmmad5bacbib98","doi-asserted-by":"publisher","first-page":"869","DOI":"10.2147\/IJN.S73628","article-title":"Osteogenic cell differentiation on H-terminated and O-terminated nanocrystalline diamond films","volume":"10","author":"Liskova","year":"2015","journal-title":"Int. J. Nanomed."},{"key":"bmmad5bacbib99","doi-asserted-by":"publisher","first-page":"2740","DOI":"10.3390\/nano11102740","article-title":"Interaction of nanodiamonds with water:impact of surface chemistry on hydrophilicity, aggregation and electrical properties","volume":"11","author":"Apr\u00e0","year":"2021","journal-title":"Nanomaterials"},{"key":"bmmad5bacbib100","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms22063086","article-title":"The marine polysaccharide ulvan confers potent osteoinductive capacity to PCL \u2010 based scaffolds for bone tissue engineering applications","volume":"22","author":"Kikionis","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"bmmad5bacbib101","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1002\/adhm.201500723","article-title":"In vivo host response and degradation of copolymer scaffolds functionalized with nanodiamonds and bone morphogenetic protein 2","volume":"5","author":"Suliman","year":"2016","journal-title":"Adv. Healthcare Mater."},{"key":"bmmad5bacbib102","author":"Rezek","year":"2017","edition":"6th edn"},{"key":"bmmad5bacbib103","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1016\/j.polymdegradstab.2012.05.038","article-title":"Hydrolytic and enzymatic degradation of a poly (\u03f5-caprolactone) network","volume":"97","author":"Castilla-cort\u00e1zar","year":"2012","journal-title":"Polym. Degrad. Stab."},{"key":"bmmad5bacbib104","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1080\/17452759.2011.605839","article-title":"Evaluation of in vitro degradation of PCL scaffolds fabricated via BioExtrusion","volume":"6","author":"Domingosa","year":"2011","journal-title":"Virtual Phys. Prototyp."},{"key":"bmmad5bacbib105","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2014\/802435","article-title":"In vitro degradation of poly(caprolactone)\/nHA composites","volume":"802435","author":"D\u00edaz","year":"2014","journal-title":"J. Nanomater."},{"key":"bmmad5bacbib106","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/membranes8010012","article-title":"Hydrolytic degradation and mechanical stability of poly(\u03f5-caprolactone)\/reduced graphene oxide membranes as scaffolds for in vitro neural tissue regeneration","volume":"8","author":"S\u00e1nchez-Gonz\u00e1lez","year":"2018","journal-title":"Membranes"},{"key":"bmmad5bacbib107","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2023.113342","article-title":"Biomedical applications of biodegradable polycaprolactone-functionalized magnetic iron oxides nanoparticles and their polymer nanocomposites","volume":"227","author":"Obisesan","year":"2023","journal-title":"Colloids Surf. B"},{"key":"bmmad5bacbib108","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1088\/1742-6596\/558\/1\/012056","article-title":"Effect of nanodiamond modification of siloxane surfaces on stem cell behaviour","volume":"588","author":"Keremidarska","year":"2014","journal-title":"J. Phys. Sci."},{"key":"bmmad5bacbib109","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1021\/acsami.6b03997","article-title":"Electrospun polyhydroxybutyrate\/poly(\u03f5-caprolactone)\/58S Sol-Gel bioactive glass hybrid scaffolds with highly improved osteogenic potential for bone tissue engineering","volume":"23","author":"Ding","year":"2016","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"bmmad5bacbib110","doi-asserted-by":"publisher","first-page":"2146","DOI":"10.1002\/pssa.200879729","article-title":"Improved adhesion, growth and maturation of human bone-derived cells on nanocrystalline diamond films","volume":"205","author":"Kopecek","year":"2008","journal-title":"Phys. Status Solidi"}],"container-title":["Biomedical Materials"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ad5bac","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ad5bac\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ad5bac","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ad5bac\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ad5bac\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ad5bac\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ad5bac\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ad5bac\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T03:03:04Z","timestamp":1721012584000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ad5bac"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,15]]},"references-count":110,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,7,15]]},"published-print":{"date-parts":[[2024,9,1]]}},"URL":"https:\/\/doi.org\/10.1088\/1748-605x\/ad5bac","relation":{},"ISSN":["1748-6041","1748-605X"],"issn-type":[{"value":"1748-6041","type":"print"},{"value":"1748-605X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,15]]},"assertion":[{"value":"Effect of nanodiamonds surface deposition on hydrophilicity, bulk degradation and in-vitro cell adhesion of 3D-printed polycaprolactone scaffolds for bone tissue engineering","name":"article_title","label":"Article Title"},{"value":"Biomedical Materials","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2024 The Author(s). Published by IOP Publishing Ltd","name":"copyright_information","label":"Copyright Information"},{"value":"2023-11-21","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-06-25","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-07-15","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}