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A tensile test was conducted to investigate the mechanical properties of the scaffolds, and the results showed that the scaffolds perform poorly at a higher SrHAp concentration because of exceeding agglomeration levels. The PVA\/SrHAp15 performed the best antibacterial activity against <jats:italic>E. coli<\/jats:italic> and <jats:italic>S. aureus<\/jats:italic> with an inhibition zone of (15.2 \u00b1 0.2) and (14.5 \u00b1 0.8), respectively. The apatite formation was more abundant in PVA\/SrHAp10 after immersion in a simulated body fluid. Cell viability results showed that the scaffold enabled the osteoblast cells to grow and proliferate. The biocompatibility of HAp and SrHAp resulted in the enhancement of cell adhesion. Based on all tests, the PVA\/SrHAp 10 scaffold shows a strong candidate for further <jats:italic>in vivo<\/jats:italic> studies.<\/jats:p>","DOI":"10.1088\/1748-605x\/ad7e92","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T23:01:30Z","timestamp":1727132490000},"page":"065021","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Electrospun polyvinyl alcohol nanofiber scaffolds incorporated strontium-substituted hydroxyapatite from sand lobster shells: synthesis, characterization, and in vitro biological properties"],"prefix":"10.1088","volume":"19","author":[{"given":"Arian Hermawan","family":"Diputra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I Kadek Hariscandra","family":"Dinatha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilam","family":"Cahyati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3095-7658","authenticated-orcid":true,"given":"Jaka Fajar","family":"Fatriansyah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhamad","family":"Taufik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1858-6890","authenticated-orcid":true,"family":"Hartatiek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9104-9333","authenticated-orcid":true,"given":"Yusril","family":"Yusuf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2024,10,7]]},"reference":[{"key":"bmmad7e92bib1","doi-asserted-by":"publisher","first-page":"e580","DOI":"10.1016\/S2666-7568(21)00172-0","article-title":"Global, regional, and national burden of bone fractures in 204 countries and territories, 1990\u20132019: a systematic analysis from the Global Burden of Disease Study 2019","volume":"2","author":"Wu","year":"2021","journal-title":"Lancet Healthy Longev."},{"key":"bmmad7e92bib2","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1302\/0301-620X.98B.36350","article-title":"Bone grafts and their substitutes","volume":"98-B","author":"Fillingham","year":"2016","journal-title":"Bone Joint J."},{"key":"bmmad7e92bib3","doi-asserted-by":"publisher","first-page":"S18","DOI":"10.1016\/j.injury.2021.01.043","article-title":"Autologous bone graft: is it still the gold standard?","volume":"52","author":"Schmidt","year":"2021","journal-title":"Injury"},{"key":"bmmad7e92bib4","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1097\/00005131-198909000-00002","article-title":"Morbidity at bone graft donor sites","volume":"3","author":"Younger","year":"1989","journal-title":"J. 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