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Additionally, the mechanical properties of PGI membrane were that the elongation at break increased to 19.9% and the tensile strength to 2.9 MPa. <jats:italic>In vitro<\/jats:italic> release studies indicated at least 48% release rate of IBC from the PGI nanofibrous membrane in 12 h, and release period up to 14 d. Antioxidant results revealed PGI membranes had fine abilities for scavenging free radical. The elimination of over 99% of <jats:italic>Staphylococcus aureus<\/jats:italic> and elimination of 54% <jats:italic>Candida albicans<\/jats:italic> demonstrated the antibacterial capacities of the PGI membrane, indicating its potential as antibacterial and antioxidant materials. Subsequent faster wound healing, lower oxidative damage for 4-HNE and 8-OHdG, further demonstrated that PGI can reduce oxidative damage at the wound and promote wound healing. These findings also suggest the potential of PGI in the field of tissue engineering.<\/jats:p>","DOI":"10.1088\/1748-605x\/adb8b2","type":"journal-article","created":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T06:24:14Z","timestamp":1740723854000},"page":"025035","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Isobavachalcone-loaded electrospun polycaprolactone\/gelatin nanofibers for antibacterial and antioxidant applications"],"prefix":"10.1088","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5557-080X","authenticated-orcid":true,"given":"Peibo","family":"Guo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyi","family":"Lv","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ao","family":"Qu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjing","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huijing","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7093-3023","authenticated-orcid":true,"given":"Zijian","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"266","published-online":{"date-parts":[[2025,2,28]]},"reference":[{"key":"bmmadb8b2bib1","doi-asserted-by":"publisher","DOI":"10.1002\/star.202200282","article-title":"Hemicellulose\u2010based nanofibers decorated in situ with silver nanoparticles for antibacterial applications","volume":"76","author":"Onditi","year":"2024","journal-title":"Starch"},{"key":"bmmadb8b2bib2","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1002\/jbm.a.37285","article-title":"Preparation and characterization of silk fibroin\/polyethylene oxide nanofiber membranes with antibacterial activity","volume":"110","author":"Lan","year":"2022","journal-title":"J. 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