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Young\u2019s modulus results revealed significant reductions in acidic conditions. Maxon\u2019s surgeon knot decreased from 516 MPa to 228 MPa, while Monocryl\u2019s surgeon knot dropped from 434 MPa to 132 MPa over 20 d. Mechanical loss was notably higher in acidic conditions, with Maxon\u2019s surgeon knot exhibiting a 65.30% reduction and Monocryl\u2019s surgeon knot showing an 82.3% decrease. Toughness declined similarly, particularly in knotted configurations. Phase maps revealed substantial structural distortion, especially in Monocryl\u2019s perpendicular orientation at pH 5, indicating severe degradation. 3D refractive index profiles demonstrated that Maxon maintained greater internal uniformity, while Monocryl showed pronounced structural disruption under acidic conditions. Maxon\u2019s stability under different pH conditions makes it suitable for long-term applications, while Monocryl\u2019s rapid degradation suggests its suitability for scenarios requiring faster material breakdown. These findings provide valuable insights for suture selection in diverse wound conditions.<\/jats:p>","DOI":"10.1088\/1748-605x\/adcb0d","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T22:54:01Z","timestamp":1744239241000},"page":"035022","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Optomechanical evaluation of knot security in Monocryl and Maxon sutures under varying pH conditions"],"prefix":"10.1088","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3901-9174","authenticated-orcid":true,"given":"Mohammed A","family":"El-Bakary","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aliaa A","family":"Nafad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nayera M","family":"El-Sayed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"266","published-online":{"date-parts":[[2025,4,17]]},"reference":[{"key":"bmmadcb0dbib1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmatsci.2024.101249","article-title":"Tuning the properties of surgical polymeric materials for improved soft-tissue wound closure and healing","volume":"143","author":"Chen","year":"2024","journal-title":"Prog. 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All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2025-02-05","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2025-04-09","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2025-04-17","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}