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The incorporation of Fe<jats:sub>3<\/jats:sub>O<jats:sub>4<\/jats:sub> nanoparticles significantly enhanced the scaffold\u2019s compressive strength and elastic modulus, while PPy increased conductivity to levels comparable to those of native neural tissue. The scaffold also exhibited superparamagnetic properties due to Fe<jats:sub>3<\/jats:sub>O<jats:sub>4<\/jats:sub> NPs, as confirmed by vibrating-sample magnetometry analysis. PBS submersion demonstrated water absorption and a 30% weight loss over 24 d. <jats:italic>In vitro<\/jats:italic> cytotoxicity tests on SH-SY5Y human neuroblastoma cells cultured on composite scaffolds confirmed cell viability, both with and without pulsed electromagnetic field stimulation. Overall, these results suggest that this scaffold is a promising candidate for neural tissue regeneration.<\/jats:p>","DOI":"10.1088\/1748-605x\/add06d","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T22:56:25Z","timestamp":1745535385000},"page":"035027","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Development and characterization of bifunctional conductive and magnetic scaffold based on polyvinyl alcohol\/polypyrrole\/magnetite composite for neural tissue engineering"],"prefix":"10.1088","volume":"20","author":[{"given":"Mohammad Hossein","family":"Golbabaei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0865-1559","authenticated-orcid":true,"given":"Fatemehsadat","family":"Pishbin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2209-2439","authenticated-orcid":true,"given":"S A Seyyed","family":"Ebrahimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nooshin","family":"Haghighipour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2025,5,6]]},"reference":[{"key":"bmmadd06dbib1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.62347\/WMDZ8890","article-title":"Recent progresses in neural tissue engineering using topographic scaffolds","volume":"13","author":"Han","year":"2024","journal-title":"Am. 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