{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T09:24:29Z","timestamp":1761211469145,"version":"build-2065373602"},"reference-count":51,"publisher":"IOP Publishing","issue":"6","license":[{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"name":"National Natural Science Foundation project","award":["81970093"],"award-info":[{"award-number":["81970093"]}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Biomed. Mater."],"published-print":{"date-parts":[[2025,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The use of covered self-expandable metal (CSEM) stents for fistulas sealing is a common clinical approach. However, these stents need to be removed once their therapeutic goals are achieved. Our study designed and fabricated a dumbbell-shaped, high-porosity, biodegradable polydioxanone weaving tracheal (PW) stent, and investigated its sealing efficacy and degradation characteristics. A tracheal defect model was created in 24 beagle dogs. Six dogs were implanted with CSEM stents, while the remaining 18 dogs received PW stents. The dogs in the CSEM and PW groups were observed for up to 8 and 14 weeks, respectively, with clinical symptoms, tracheoscopy, computed tomography scans, and fluoroscopy monitored. Subsequently, the stents were retrieved to observe morphological changes, and measure mechanical properties. The PW stents exhibited excellent airtightness, with significantly fewer complications such as stent displacement and granulation tissue hyperplasia compared to the CSEM stents. The tracheal tissue response to the PW stent was relatively mild. After PW stent implantation, collagen fiber deposition at the defect site gradually increased, and cartilage structure regeneration was observed in later stages. Notably, cilia were largely absent in the tracheal epithelium, with squamous metaplasia observed even in the later stages of the experiment following PW stent implantation. Additionally, the PW stents remained mostly intact in the canine airways until week 12, and were completely degraded and disappeared from the canine airways at week 14, without causing severe complications. The PW stent, featuring excellent biocompatibility and uniform degradation in the large-animal airway, demonstrated clinical effectiveness in sealing tracheal defects.<\/jats:p>","DOI":"10.1088\/1748-605x\/ae11e5","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:50:52Z","timestamp":1760136652000},"page":"065014","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["The sealing effect and degradation of polydioxanone weaving tracheal stents in a canine airway defect model"],"prefix":"10.1088","volume":"20","author":[{"given":"Haihua","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1913-8945","authenticated-orcid":true,"given":"Peize","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyue","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanxue","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongxin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5093-0693","authenticated-orcid":true,"given":"Zheng","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"266","published-online":{"date-parts":[[2025,10,23]]},"reference":[{"key":"bmmae11e5bib1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/17534666231164541","type":"journal-article","article-title":"Bronchoscopic interventions for bronchopleural fistulas","volume":"17","author":"Jin","year":"2023","journal-title":"Ther. Adv. Respir. Dis."},{"key":"bmmae11e5bib2","doi-asserted-by":"publisher","first-page":"226","DOI":"10.21037\/jtd-22-1545","type":"journal-article","article-title":"Incidence of bronchopleural fistula after pneumonectomy in an era of revolution","volume":"15","author":"Khaitan","year":"2023","journal-title":"J. Thoracic Dis."},{"key":"bmmae11e5bib3","doi-asserted-by":"publisher","first-page":"5889","DOI":"10.21037\/jtd-2023-13","type":"journal-article","article-title":"Bronchopleural fistula after lobectomy: who is at risk in the modern era?","volume":"15","author":"Tasoudis","year":"2023","journal-title":"J. Thoracic Dis."},{"key":"bmmae11e5bib4","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.31439","type":"journal-article","article-title":"Safety and efficacy of fully covered self-expandable metal stents for benign upper gastrointestinal strictures beyond the esophagus","volume":"14","author":"Randhawa","year":"2022","journal-title":"Cureus"},{"key":"bmmae11e5bib5","doi-asserted-by":"publisher","first-page":"6357","DOI":"10.3748\/wjg.v27.i38.6357","type":"journal-article","article-title":"Fully covered metal biliary stents: a review of the literature","volume":"27","author":"Lam","year":"2021","journal-title":"World J. Gastroenterol."},{"key":"bmmae11e5bib6","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1111\/1759-7714.13707","type":"journal-article","article-title":"Clinical outcomes and survival following placement of self-expandable metallic stents for central airway stenosis and fistula","volume":"12","author":"Usuda","year":"2021","journal-title":"Thoracic Cancer"},{"key":"bmmae11e5bib7","doi-asserted-by":"publisher","first-page":"S1274","DOI":"10.21037\/jtd.2019.05.05","type":"journal-article","article-title":"Customized airway stenting for bronchopleural fistula after pulmonary resection by interventional technique: single-center study of 148 consecutive patients","volume":"11","author":"Harris","year":"2019","journal-title":"J. Thoracic Dis."},{"key":"bmmae11e5bib8","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1159\/000530421","type":"journal-article","article-title":"Airway stents from now to the future: a narrative review","volume":"102","author":"Li","year":"2023","journal-title":"Respiration"},{"key":"bmmae11e5bib9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2020.110405","type":"journal-article","article-title":"The role of bioresorbable intraluminal airway stents in pediatric tracheobronchial obstruction: a systematic review","volume":"139","author":"Stramiello","year":"2020","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"bmmae11e5bib10","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1097\/mcp.0000000000001032","type":"journal-article","article-title":"Advancements in airway stents: a comprehensive update","volume":"30","author":"Aravena","year":"2024","journal-title":"Curr. Opin. Pulm. Med."},{"key":"bmmae11e5bib11","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1016\/j.cps.2022.12.011","type":"journal-article","article-title":"Minimally invasive techniques for facial rejuvenation utilizing polydioxanone threads","volume":"50","author":"Kochhar","year":"2023","journal-title":"Clin. Plast. Surg."},{"key":"bmmae11e5bib12","first-page":"942","type":"journal-article","article-title":"Primary results of chest wall reconstruction with polydioxanone mesh on animals","volume":"16","author":"Zheng","year":"2012","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"bmmae11e5bib13","doi-asserted-by":"publisher","first-page":"330","DOI":"10.20524\/aog.2020.0482","type":"journal-article","article-title":"Biodegradable esophageal stents for the treatment of refractory benign esophageal strictures","volume":"33","author":"Gkolfakis","year":"2020","journal-title":"Ann. Gastroenterol."},{"key":"bmmae11e5bib14","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1016\/j.gie.2017.10.042","type":"journal-article","article-title":"A pilot study of endoscopically inserted biodegradable biliary stents in the treatment of benign biliary strictures and cystic duct leaks","volume":"87","author":"Siiki","year":"2018","journal-title":"Gastrointest Endos."},{"key":"bmmae11e5bib15","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1002\/ppul.23340","type":"journal-article","article-title":"Initial experience with a new biodegradable airway stent in children: is this the stent we were waiting for?","volume":"51","author":"Ant\u00f3n-Pacheco","year":"2016","journal-title":"Pediatr. Pulmonol."},{"key":"bmmae11e5bib16","doi-asserted-by":"publisher","first-page":"961","DOI":"10.17219\/acem\/94391","type":"journal-article","article-title":"Biodegradable airway stents: novel treatment of airway obstruction in children","volume":"28","author":"Zaj\u0105c","year":"2019","journal-title":"Adv. Clin. Exp. Med."},{"key":"bmmae11e5bib17","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1186\/s12890-015-0160-6","type":"journal-article","article-title":"Biodegradable polydioxanone stents in the treatment of adult patients with tracheal narrowing","volume":"15","author":"Stehlik","year":"2015","journal-title":"BMC Pulm. Med."},{"key":"bmmae11e5bib18","doi-asserted-by":"publisher","first-page":"ezac380","DOI":"10.1093\/ejcts\/ezac380","type":"journal-article","article-title":"Histological and structural effects of biodegradable polydioxanone stents in the rabbit trachea","volume":"62","author":"Morante-Valverde","year":"2022","journal-title":"Eur. J. Cardio-thorac Surg."},{"key":"bmmae11e5bib19","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/j.jtcvs.2011.08.002","type":"journal-article","article-title":"Novel biodegradable polydioxanone stents in a rabbit airway model","volume":"143","author":"Novotny","year":"2012","journal-title":"J. Thoracic Cardiovasc. Surg."},{"key":"bmmae11e5bib20","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1002\/jbm.b.30319","type":"journal-article","article-title":"Mechanical properties and in vitro degradation of bioresorbable fibers and expandable fiber-based stents","volume":"74","author":"Zilberman","year":"2005","journal-title":"J. Biomed. Mater. Res. B"},{"key":"bmmae11e5bib21","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1007\/s10388-022-00909-6","type":"journal-article","article-title":"Pivotal trial of a biodegradable stent for patients with refractory benign esophageal stricture","volume":"19","author":"Yano","year":"2022","journal-title":"Esophagus"},{"key":"bmmae11e5bib22","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1089\/fpsam.2021.0421","type":"journal-article","article-title":"Septal perforation repair using a temporoparietal fascia and polydioxanone plate construct: a multi-institutional analysis","volume":"25","author":"Davis","year":"2023","journal-title":"Facial Plast. Surg. Aesthet. Med."},{"key":"bmmae11e5bib23","doi-asserted-by":"publisher","first-page":"2059","DOI":"10.1097\/scs.0000000000006487","type":"journal-article","article-title":"In vitro and in vivo biocompatibility and degradability evaluation of modified polydioxanone plate","volume":"31","author":"Kim","year":"2020","journal-title":"J. Craniofacial Surg."},{"key":"bmmae11e5bib24","doi-asserted-by":"publisher","DOI":"10.1088\/1748-605X\/ad6ac6","type":"journal-article","article-title":"Study on in vivo and in vitro degradation of polydioxanone weaving tracheal stents","volume":"19","author":"Huang","year":"2024","journal-title":"Biomed. Mater."},{"key":"bmmae11e5bib25","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1007\/s12471-020-01442-w","type":"journal-article","article-title":"The 2010s in clinical drug-eluting stent and bioresorbable scaffold research: a Dutch perspective","volume":"28","author":"Kawashima","year":"2020","journal-title":"Netherlands Heart J."},{"key":"bmmae11e5bib26","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1016\/j.arbres.2020.02.008","type":"journal-article","article-title":"Reactivity study of a biodegradable polydioxanone tracheal stent in a rabbit model","volume":"56","author":"Rodriguez-Zapater","year":"2020","journal-title":"Arch. Bronconeumol."},{"key":"bmmae11e5bib27","doi-asserted-by":"publisher","first-page":"ezae095","DOI":"10.1093\/ejcts\/ezae095","type":"journal-article","article-title":"Biodegradable polydioxanone stents: histologic and structural effects in an experimental model of tracheal stenosis","volume":"65","author":"Morante-Valverde","year":"2024","journal-title":"Eur. J. Cardio-thorac Surg."},{"key":"bmmae11e5bib28","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/j.anl.2018.10.010","type":"journal-article","article-title":"Characterization of the biomechanical properties of canine trachea using a customized 3D-printed apparatus","volume":"46","author":"Lee","year":"2019","journal-title":"Auris Nasus Larynx"},{"key":"bmmae11e5bib29","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1016\/j.vaa.2022.04.003","type":"journal-article","article-title":"Comparison of blind and endoscopic-guided orotracheal intubation on laryngeal and tracheal damage in domestic rabbits (Oryctolagus cuniculus)","volume":"49","author":"Reabel","year":"2022","journal-title":"Vet. Anaesth. Analg."},{"key":"bmmae11e5bib30","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1055\/s-0034-1396681","type":"journal-article","article-title":"Clinical application of fully covered self-expandable metal stents in the treatment of bronchial fistula","volume":"64","author":"Cao","year":"2016","journal-title":"Thorac. Cardiovasc. Surg."},{"key":"bmmae11e5bib31","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.resinv.2018.09.002","type":"journal-article","article-title":"Fully covered self-expandable metallic stents for malignant airway disorders","volume":"57","author":"Ishida","year":"2019","journal-title":"Respir. Investig."},{"key":"bmmae11e5bib32","doi-asserted-by":"publisher","first-page":"643","DOI":"10.3969\/j.issn.1672-5220.2014.05.018","type":"journal-article","article-title":"Development and mechanical properties of a novel woven artificial tracheal stent","volume":"31","author":"Ben-sheng","year":"2014","journal-title":"J. Donghua Univ."},{"key":"bmmae11e5bib33","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1097\/ccm.0000000000004771","type":"journal-article","article-title":"Bronchopleural fistula in the mechanically ventilated patient: a concise review","volume":"49","author":"Grotberg","year":"2021","journal-title":"Crit. Care Med."},{"key":"bmmae11e5bib34","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1016\/j.rcl.2016.05.014","type":"journal-article","article-title":"Imaging of diseases of the large airways","volume":"54","author":"Little","year":"2016","journal-title":"Radiol. Clin. N. Am."},{"key":"bmmae11e5bib35","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1159\/000368614","type":"journal-article","article-title":"Fully covered self-expandable metal stent in tracheobronchial disorders: clinical experience","volume":"89","author":"Marchese","year":"2015","journal-title":"Respiration"},{"key":"bmmae11e5bib36","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1016\/j.gie.2022.06.001","type":"journal-article","article-title":"Comparison of no stent fixation, endoscopic suturing, and a novel over-the-scope clip for stent fixation in preventing migration of fully covered self-expanding metal stents: a retrospective comparative study (with video)","volume":"96","author":"Park","year":"2022","journal-title":"Gastrointest Endos."},{"key":"bmmae11e5bib37","doi-asserted-by":"publisher","first-page":"2517","DOI":"10.1002\/ppul.27056","type":"journal-article","article-title":"Further experience with polydioxanone airway stents in children","volume":"59","author":"Morante-Valverde","year":"2024","journal-title":"Pediatr. Pulmonol."},{"key":"bmmae11e5bib38","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0066-2021","type":"journal-article","article-title":"Airway granulation response to lung-implantable medical devices: a concise overview","volume":"30","author":"Roodenburg","year":"2021","journal-title":"Eur. Respir. Rev."},{"key":"bmmae11e5bib39","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0192557","type":"journal-article","article-title":"Flexible endoscopy for pediatric tracheobronchial metallic stent placement, maintenance and long-term outcomes","volume":"13","author":"Soong","year":"2018","journal-title":"PLoS One"},{"key":"bmmae11e5bib40","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1016\/S0003-4975(01)03460-9","type":"journal-article","article-title":"Experience with ultraflex expandable metallic stents in the management of endobronchial pathology","volume":"73","author":"Madden","year":"2002","journal-title":"Ann. Thorac. Surg."},{"key":"bmmae11e5bib41","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1016\/j.healun.2009.12.011","type":"journal-article","article-title":"A retrospective study of silicone stent placement for management of anastomotic airway complications in lung transplant recipients: short- and long-term outcomes","volume":"29","author":"Dutau","year":"2010","journal-title":"J. Heart Lung Transplant."},{"key":"bmmae11e5bib42","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1159\/000442054","type":"journal-article","article-title":"Biodegradable airway stents\u2014bench to bedside: a comprehensive review","volume":"90","author":"Dutau","year":"2015","journal-title":"Respiration"},{"key":"bmmae11e5bib43","doi-asserted-by":"publisher","first-page":"196","DOI":"10.3390\/jfb14040196","type":"journal-article","article-title":"Current status and future outlook of additive manufacturing technologies for the reconstruction of the trachea","volume":"14","author":"Lee","year":"2023","journal-title":"J. Funct. Biomater."},{"key":"bmmae11e5bib44","doi-asserted-by":"publisher","first-page":"1870","DOI":"10.1016\/j.athoracsur.2007.07.026","type":"journal-article","article-title":"Complications of silicone stent insertion in patients with expiratory central airway collapse","volume":"84","author":"Murgu","year":"2007","journal-title":"Ann. Thorac. Surg."},{"key":"bmmae11e5bib45","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.bioactmat.2019.01.001","type":"journal-article","article-title":"In vitro degradation and biocompatibility evaluation of typical biodegradable metals (Mg\/Zn\/Fe) for the application of tracheobronchial stenosis","volume":"4","author":"Li","year":"2019","journal-title":"Bioact Mater."},{"key":"bmmae11e5bib46","doi-asserted-by":"publisher","first-page":"1967","DOI":"10.1016\/j.jpedsurg.2016.09.020","type":"journal-article","article-title":"Biodegradable polydioxanone stent as a new treatment strategy for tracheal stenosis in a rabbit model","volume":"51","author":"Kawahara","year":"2016","journal-title":"J. Pediatr. Surg."},{"key":"bmmae11e5bib47","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/S0141-3910(00)00003-3","type":"journal-article","article-title":"Microbial degradation of poly (p-dioxanone) I. Isolation of degrading microorganisms and microbial decomposition in pure culture","volume":"68","author":"Nishida","year":"2000","journal-title":"Polym. Degrad. Stab."},{"key":"bmmae11e5bib48","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1111\/wrr.12937","type":"journal-article","article-title":"Myofibroblast progeny in wound biology and wound healing studies","volume":"29","author":"Monika","year":"2021","journal-title":"Wound Repair Regen."},{"key":"bmmae11e5bib49","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1163\/156856201744489","type":"journal-article","article-title":"Scaffold design and fabrication technologies for engineering tissues\u2013state of the art and future perspectives","volume":"12","author":"Hutmacher","year":"2001","journal-title":"J. Biomater. Sci. Polym. Ed."},{"key":"bmmae11e5bib50","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2025.123192","type":"journal-article","article-title":"Micropore structure engineering of injectable granular hydrogels via controlled liquid-liquid phase separation facilitates regenerative wound healing in mice and pigs","volume":"318","author":"Guan","year":"2025","journal-title":"Biomaterials"},{"key":"bmmae11e5bib51","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.actbio.2015.09.011","type":"journal-article","article-title":"Agent-based modeling of porous scaffold degradation and vascularization: optimal scaffold design based on architecture and degradation dynamics","volume":"27","author":"Mehdizadeh","year":"2015","journal-title":"Acta Biomater."}],"container-title":["Biomedical Materials"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ae11e5","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ae11e5\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ae11e5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ae11e5\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ae11e5\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ae11e5\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ae11e5\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ae11e5\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T09:19:56Z","timestamp":1761211196000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-605X\/ae11e5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,23]]},"references-count":51,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,10,23]]},"published-print":{"date-parts":[[2025,11,1]]}},"URL":"https:\/\/doi.org\/10.1088\/1748-605x\/ae11e5","relation":{},"ISSN":["1748-6041","1748-605X"],"issn-type":[{"type":"print","value":"1748-6041"},{"type":"electronic","value":"1748-605X"}],"subject":[],"published":{"date-parts":[[2025,10,23]]},"assertion":[{"value":"The sealing effect and degradation of polydioxanone weaving tracheal stents in a canine airway defect model","name":"article_title","label":"Article Title"},{"value":"Biomedical Materials","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2025 The Author(s). Published by IOP Publishing Ltd","name":"copyright_information","label":"Copyright Information"},{"value":"2025-04-09","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2025-10-10","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2025-10-23","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}