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Compared with Ti, BT\u2013Ti effectively promoted the expression of osteoblast-related genes and proteins in MC3T3-E1 cells, and ZnO\/BT coating material further enhanced the promotion of bone differentiation of cells. Additionally, ZnO\/BT\u2013Ti significantly inhibited the proliferation of P.g and the formation of biofilm. Therefore, ZnO\/BT composite ceramic coating has a synergistic effect on osteogenic differentiation of MC3T3-E1 cells, and significant antibacterial properties, providing the preliminary experimental support for the development of new artificial bone materials.<\/jats:p>","DOI":"10.1088\/1748-605x\/ae8947","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T22:52:23Z","timestamp":1783723943000},"page":"045017","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["An\n                    <i>in vitro<\/i>\n                    study of osteogenic and antibacterial properties of ZnO\u2013BaTiO\n                    <sub>3<\/sub>\n                    coated titanium"],"prefix":"10.1088","volume":"21","author":[{"given":"Yujie","family":"Tao","sequence":"first","affiliation":[{"name":"Liaoning Provincial Key Laboratory of Oral Diseases"},{"name":"Taikang Tongji (Wuhan) Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingyu","family":"Xu","sequence":"additional","affiliation":[{"name":"Liaoning Provincial Key Laboratory of Oral Diseases"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilai","family":"Jiao","sequence":"additional","affiliation":[{"name":"Chinese Academy of Sciences Shenyang Branch"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4921-4310","authenticated-orcid":true,"given":"Xiaohan","family":"Liu","sequence":"additional","affiliation":[{"name":"Liaoning Provincial Key Laboratory of Oral Diseases"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2026,7,22]]},"reference":[{"key":"bmmae8947bib1","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1038\/s41368-024-00327-7","type":"journal-article","article-title":"Personalized bioceramic grafts for craniomaxillofacial bone regeneration","volume":"16","author":"Carvalho","year":"2024","journal-title":"Int. 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