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Breath Res."],"published-print":{"date-parts":[[2018,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    A sensitive, rapid and easy operated sensor for hydrogen peroxide (H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    ) determination in exhaled breath was developed in this study. The polyaniline (PANI) film and Cu nanoparticles (NPs) were successively electrochemical deposited on the surface of the three-dimensional nickel foam (NF), i.e., synthetized nano-Cu\/polyaniline\/NF. The Ni foam facilitates the charge and mass transfer, and it also provides a large amount of anchoring sites for Cu NP deposition. The synergistic electro-catalytic actions between Cu NPs and PANI highly enhanced the reduction current of H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    . Under the optimized conditions, the linear range for monitoring H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    extends from 0.01 to 500 nM (\n                    <jats:italic>R<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a00.998), and the limit of detection is 0.0026 nM. Integrating with collection of exhaled breath in a fritted midget bubbler, the developed sensor can clearly identify the difference of H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    levels between the smokers and non-smokers, as well as before and after smoking for these subjects. Its application performance indicates the developed sensor possesses a great potential for routine analysis of H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    in exhaled breath.\n                  <\/jats:p>","DOI":"10.1088\/1752-7163\/aaa672","type":"journal-article","created":{"date-parts":[[2018,1,10]],"date-time":"2018-01-10T04:47:04Z","timestamp":1515559624000},"page":"036001","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Ultrasensitive sensor based on nano-Cu\/polyaniline\/nickel foam for monitoring H\n                    <sub>2<\/sub>\n                    O\n                    <sub>2<\/sub>\n                    in exhaled breath"],"prefix":"10.1088","volume":"12","author":[{"given":"Aifeng","family":"Liu","sequence":"first","affiliation":[{"name":"CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liang","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongguang","family":"Shi","sequence":"additional","affiliation":[{"name":"Agro-Environmental Protection Institute, Ministry of Agriculture, Tianjin 300191,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0800-0983","authenticated-orcid":false,"given":"Zongshan","family":"Zhao","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Tian","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2018,3,6]]},"reference":[{"key":"jbraaa672bib1","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.2174\/092986711795328418","type":"journal-article","article-title":"Exhaled breath condensate in asthma: from bench to bedside","volume":"18","author":"Loukides","year":"2011","journal-title":"Curr. 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All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2017-09-11","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2018-01-10","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2018-03-06","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}