{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T17:37:51Z","timestamp":1773509871895,"version":"3.50.1"},"reference-count":46,"publisher":"IOP Publishing","issue":"2","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/publishingsupport.iopscience.iop.org\/iop-standard\/v1"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003409","name":"GABA International","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003409","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["J. Breath Res."],"published-print":{"date-parts":[[2019,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Aim<\/jats:italic>\n                    : This randomized controlled cross-over-design-study investigated short-term effects on oral malodour of a zinc-lactate-containing mouthwash.\n                    <jats:italic>Materials and Methods<\/jats:italic>\n                    : Sixteen subjects (18\u201365 years) with an organoleptic score (OLS) \u22652 were included. Following rinses were used: (A) a zinc-lactate-containing mouthwash (10 ml\/30 s); (B) a zinc-lactate-containing mouthwash (15 ml\/60 s); (C) a rinse without zinc-lactate (3 droplets\/10 ml tap water\/30 s) and (D) tap water (10 ml\/30 s). Each formulation was evaluated by two blinded examiners comparing OLS and three volatile-sulphur-compounds (VSC; H\n                    <jats:sub>2<\/jats:sub>\n                    S (hydrogen sulphide), CH\n                    <jats:sub>3<\/jats:sub>\n                    SH (methyl mercaptan) and (CH\n                    <jats:sub>3<\/jats:sub>\n                    )\n                    <jats:sub>2<\/jats:sub>\n                    S (dimethyl sulphide)) before, 1 and 3 h after rinsing. Subject\u2019s perception was investigated with a visual-analogue-scale. Linear mixed models were used to compare all parameters simultaneously with respect to the four treatment groups with a significance level\n                    <jats:italic>\u03b1<\/jats:italic>\n                    \u00a0&lt;\u00a00.05.\n                    <jats:italic>Results<\/jats:italic>\n                    : OLS was significantly reduced by A and B compared to C and D after 3 h (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.006). The sum of the 3 VSCs as well as H\n                    <jats:sub>2<\/jats:sub>\n                    S alone were significantly reduced by rinses A and B after 1 and 3 h compared to rinses C and D (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). Significant differences were found between the four rinses for \u2018Taste\u2019 (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.003), for \u2018Change of mouth feeling\u2019 (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.001), for \u2018Feeling of freshness\u2019 (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.002) and for \u2018Effectiveness\u2019 (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.002) in favour of A &amp; B.\n                    <jats:italic>Conclusion<\/jats:italic>\n                    : A zinc-lactate-containing mouthwash reduced OLS and VSC over a period of 3 h with favourable patient reported outcomes.\n                  <\/jats:p>","DOI":"10.1088\/1752-7163\/aaf401","type":"journal-article","created":{"date-parts":[[2018,11,26]],"date-time":"2018-11-26T17:30:28Z","timestamp":1543253428000},"page":"026005","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["A randomized cross-over short-term study on the short-term effects of a zinc-lactate containing mouthwash against oral malodour"],"prefix":"10.1088","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4697-6984","authenticated-orcid":false,"given":"Pia-Merete","family":"Jerv\u00f8e-Storm","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hendrik","family":"Schulze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f8ren","family":"Jepsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"266","published-online":{"date-parts":[[2019,3,1]]},"reference":[{"key":"jbraaf401bib1","first-page":"257","type":"journal-article","article-title":"Examination, classification, and treatment of halitosis\u2014clinical perspectives","volume":"66","author":"Yaegaki","year":"2000","journal-title":"J. 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