{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T16:55:36Z","timestamp":1770742536952,"version":"3.49.0"},"reference-count":63,"publisher":"IOP Publishing","issue":"3","license":[{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/publishingsupport.iopscience.iop.org\/iop-standard\/v1"},{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"name":"Wuhan University Specific Fund for Major School-level Internationalization Initiatives","award":["WHU-GJZDZX-PT07"],"award-info":[{"award-number":["WHU-GJZDZX-PT07"]}]},{"name":"the International Institute of Spatial Lifecourse Health"},{"name":"Jiangxi Provincial 03 Special Foundation and 5G Program","award":["20224ABC03A05"],"award-info":[{"award-number":["20224ABC03A05"]}]},{"name":"Hubei Provincial Engineering Research Center of Comprehensive Care for Heart-Brain Diseases"},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["42271433"],"award-info":[{"award-number":["42271433"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["J. Breath Res."],"published-print":{"date-parts":[[2023,7,1]]},"abstract":"Abstract<\/jats:title>\n PM2.5<\/jats:sub> is a well-known airborne hazard to cause various diseases. Evidence suggests that air pollution exposure contributes to the occurrence of pulmonary nodules. Pulmonary nodules detected on the computed tomography scans can be malignant or progress to malignant during follow-up. But the evidence of the association between PM2.5<\/jats:sub> exposure and pulmonary nodules was limited. To examine potential associations of exposures to PM2.5<\/jats:sub> and its major chemical constituents with the prevalence of pulmonary nodules. A total of 16\u2009865 participants were investigated from eight physical examination centers in China from 2014 to 2017. The daily concentrations of PM2.5<\/jats:sub> and its five components were estimated by high-resolution and high-quality spatiotemporal datasets of ground-level air pollutants in China. The logistic regression and the quantile-based g-computation models were used to assess the single and mixture impact of air pollutant PM2.5<\/jats:sub> and its components on the risk of pulmonary nodules, respectively. Each 1 mg m\u22123<\/jats:sup> increase in PM2.5<\/jats:sub> (OR 1.011 (95% CI: 1.007\u20131.014)) was positively associated with pulmonary nodules. Among five PM2.5<\/jats:sub> components, in single-pollutant effect models, every 1 \u03bc<\/jats:italic>g m\u22123<\/jats:sup> increase in organic matter (OM), black carbon (BC), and NO3<\/jats:sub>\n \u2212<\/jats:sup> elevated the risk of pulmonary nodule prevalence by 1.040 (95% CI: 1.025\u20131.055), 1.314 (95% CI: 1.209\u20131.407) and 1.021 (95% CI: 1.007\u20131.035) fold, respectively. In mixture-pollutant effect models, the joint effect of every quintile increase in PM2.5<\/jats:sub> components was 1.076 (95% CI: 1.023\u20131.133) fold. Notably, NO3<\/jats:sub>\n \u2212<\/jats:sup> BC and OM contributed higher risks of pulmonary nodules than other PM2.5<\/jats:sub> components. And the NO3<\/jats:sub>\n \u2212<\/jats:sup> particles were identified to have the highest contribution. The impacts of PM2.5<\/jats:sub> components on pulmonary nodules were consistent across gender and age.These findings provide important evidence for the positive correlation between exposure to PM2.5<\/jats:sub> and pulmonary nodules in China and identify that NO3<\/jats:sub>\n \u2212<\/jats:sup> particles have the highest contribution to the risk.<\/jats:p>","DOI":"10.1088\/1752-7163\/accbe4","type":"journal-article","created":{"date-parts":[[2023,4,11]],"date-time":"2023-04-11T18:29:55Z","timestamp":1681237795000},"page":"036003","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Association between one-year exposure to air pollution and the prevalence of pulmonary nodules in China"],"prefix":"10.1088","volume":"17","author":[{"given":"Yuanyuan","family":"Cao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhanpeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Lei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohui","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Gang","family":"She","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjing","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shujuan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Jia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9821-0297","authenticated-orcid":true,"given":"Hongliang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"266","published-online":{"date-parts":[[2023,4,27]]},"reference":[{"key":"jbraccbe4bib1","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1007\/s40572-017-0168-6","type":"journal-article","article-title":"The interplay of climate change and air pollution on health","volume":"4","author":"Orru","year":"2017","journal-title":"Curr. 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