{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T17:49:58Z","timestamp":1788025798373,"version":"build-2784847793"},"reference-count":142,"publisher":"IOP Publishing","issue":"1","license":[{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/page\/copyright"},{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"name":"Korean Government","award":["NRF grant 2022R1A5A2027161"],"award-info":[{"award-number":["NRF grant 2022R1A5A2027161"]}]},{"name":"Ministry of Trade, Industry & Energy","award":["Alchemist Project 1415180884 (20012378)"],"award-info":[{"award-number":["Alchemist Project 1415180884 (20012378)"]}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Biofabrication"],"published-print":{"date-parts":[[2025,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Vascular diseases are complex conditions orchestrated by multiple factors, including cellular components, biochemical stimuli, and mechanical forces. Despite the advancement of numerous therapeutic approaches, the global mortality associated with the diseases continues to escalate owing to a lack of understanding of the underlying pathologies. Tissue engineering and computational strategies have been recently developed to investigate diseased blood vessels from multifactorial perspective, enabling more accurate prediction of disease progression and opening new avenues for preclinical advances. This review focuses on <jats:italic>in vitro<\/jats:italic> and in silico blood vessel models to elucidate the pathomechanisms of vascular diseases. Following a discussion of biofabrication and computational modeling strategies, the recent research that utilizes the models of various blood vessel diseases, such as atherosclerosis, aneurysms, varicose veins, and thrombosis, are introduced. Finally, current breakthroughs, existing challenges, and outlooks in the field are described.<\/jats:p>","DOI":"10.1088\/1758-5090\/ad8034","type":"journal-article","created":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T22:57:04Z","timestamp":1727391424000},"page":"012001","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["3D engineering of diseased blood vessels for integrative in vitro\u2013in silico mechanobiology study"],"prefix":"10.1088","volume":"17","author":[{"given":"Wonbin","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Seong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Ju","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won-Woo","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seok-Hyeon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongjun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Ho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sik","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sae-Ock","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minjun","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5869-4330","authenticated-orcid":true,"given":"Dong-Woo","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6693-0003","authenticated-orcid":true,"given":"Byoung Soo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2024,10,24]]},"reference":[{"key":"bfad8034bib1","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1016\/S0140-6736(05)62751-1","article-title":"The blood","volume":"349","author":"Jones","year":"1997","journal-title":"Lancet"},{"key":"bfad8034bib2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.21474","article-title":"Tennis courts in the human body: a review of the misleading metaphor in medical literature","volume":"14","author":"Rao","year":"2022","journal-title":"Cureus"},{"key":"bfad8034bib3","author":"Jang","year":"2023"},{"key":"bfad8034bib4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/ar2193","article-title":"Vasculitis: mechanisms involved and clinical manifestations","volume":"9","author":"Guillevin","year":"2007","journal-title":"Arthritis Res. Ther."},{"key":"bfad8034bib5","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1007\/s12551-021-00815-8","article-title":"Microfluidic models of the human circulatory system: versatile platforms for exploring mechanobiology and disease modeling","volume":"13","author":"Nguyen","year":"2021","journal-title":"Biophys. Rev."},{"key":"bfad8034bib6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1146\/annurev-bioeng-092419-060810","article-title":"Vascular mechanobiology: homeostasis, adaptation, and disease","volume":"23","author":"Humphrey","year":"2021","journal-title":"Annu. Rev. Biomed. Eng."},{"key":"bfad8034bib7","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1007\/s00281-022-00925-9","volume":"vol 44","author":"Harper","year":"2022"},{"key":"bfad8034bib8","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202200203","article-title":"Engineering densely packed adipose tissue via environmentally controlled in\u2010bath 3D bioprinting","volume":"32","author":"Ahn","year":"2022","journal-title":"Adv. Funct. Mater."},{"key":"bfad8034bib9","doi-asserted-by":"publisher","DOI":"10.1002\/smtd.202100072","article-title":"Construction of tissue\u2010level cancer\u2010vascular model with high\u2010precision position control via in situ 3D cell printing","volume":"5","author":"Kim","year":"2021","journal-title":"Small Methods"},{"key":"bfad8034bib10","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202001693","article-title":"Flexible adipose\u2010vascular tissue assembly using combinational 3D printing for volume\u2010stable soft tissue reconstruction","volume":"10","author":"Cho","year":"2021","journal-title":"Adv. Healthcare Mater."},{"key":"bfad8034bib11","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202308815","article-title":"Laminin\u2010augmented decellularized extracellular matrix ameliorating neural differentiation and neuroinflammation in human mini\u2010brains","volume":"20","author":"Bae","year":"2023","journal-title":"Small"},{"key":"bfad8034bib12","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202301015","article-title":"Engineering of uniform epidermal layers via sacrificial gelatin bioink\u2010assisted 3D extrusion bioprinting of skin","volume":"12","author":"Ahn","year":"2023","journal-title":"Adv. Healthcare Mater."},{"key":"bfad8034bib13","doi-asserted-by":"publisher","first-page":"7696","DOI":"10.1038\/s41467-023-43586-4","article-title":"3D bioprinted multilayered cerebrovascular conduits to study cancer extravasation mechanism related with vascular geometry","volume":"14","author":"Park","year":"2023","journal-title":"Nat. Commun."},{"key":"bfad8034bib14","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1038\/s41536-021-00155-x","article-title":"Cellularized small-caliber tissue-engineered vascular grafts: looking for the ultimate gold standard","volume":"6","author":"Fayon","year":"2021","journal-title":"npj Regen. Med."},{"key":"bfad8034bib15","doi-asserted-by":"publisher","first-page":"5742","DOI":"10.1038\/s41598-020-62768-4","article-title":"Tortuosity-powered microfluidic device for assessment of thrombosis and antithrombotic therapy in whole blood","volume":"10","author":"Luna","year":"2020","journal-title":"Sci. Rep."},{"key":"bfad8034bib16","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202202093","article-title":"Blood\u2010lymphatic integrated system with heterogeneous melanoma spheroids via in\u2010bath three\u2010dimensional bioprinting for modelling of combinational targeted therapy","volume":"9","author":"Cho","year":"2022","journal-title":"Adv. Sci."},{"key":"bfad8034bib17","doi-asserted-by":"publisher","first-page":"326","DOI":"10.3390\/mi13020326","article-title":"The biofabrication of diseased artery In vitro models","volume":"13","author":"Pan","year":"2022","journal-title":"Micromachines"},{"key":"bfad8034bib18","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2021.100106","article-title":"The mechanical characterization of blood vessels and their substitutes in the continuous quest for physiological-relevant performances. A critical review","volume":"10","author":"Camas\u00e3o","year":"2021","journal-title":"Mater. Today Bio"},{"key":"bfad8034bib19","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1515\/ntrev-2019-0005","article-title":"Mechanical contribution of vascular smooth muscle cells in the tunica media of artery","volume":"8","author":"Mozafari","year":"2019","journal-title":"Nanotechnol. Rev."},{"key":"bfad8034bib20","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2015.00112","article-title":"Age-related vascular stiffening: causes and consequences","volume":"6","author":"Kohn","year":"2015","journal-title":"Front. Genet."},{"key":"bfad8034bib21","first-page":"155","article-title":"Mechanical properties of normal and diseased cerebrovascular system","volume":"2","author":"Ebrahimi","year":"2009","journal-title":"J. Vasc. Interv. Neurol."},{"key":"bfad8034bib22","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1111\/apha.12725","article-title":"Effects of shear stress on endothelial cells: go with the flow","volume":"219","author":"Chistiakov","year":"2017","journal-title":"Acta Physiol."},{"key":"bfad8034bib23","article-title":"Physiology, cardiovascular hemodynamics","author":"Pollock","year":"2017"},{"key":"bfad8034bib24","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2023.1259280","article-title":"Role of blood flow in endothelial functionality: a review","volume":"11","author":"Zhou","year":"2023","journal-title":"Front. Cell Dev. Biol."},{"key":"bfad8034bib25","doi-asserted-by":"publisher","first-page":"106","DOI":"10.3390\/bioengineering8080106","article-title":"Engineering and monitoring 3D cell constructs with time-evolving viscoelasticity for the study of liver fibrosis In vitro","volume":"8","author":"Cacopardo","year":"2021","journal-title":"Bioengineering"},{"key":"bfad8034bib26","doi-asserted-by":"publisher","first-page":"3076","DOI":"10.3892\/mmr.2017.6401","article-title":"Low shear stress induced autophagy alleviates cell apoptosis in HUVECs","volume":"15","author":"Dong","year":"2017","journal-title":"Mol. Med. Rep."},{"key":"bfad8034bib27","doi-asserted-by":"publisher","first-page":"0043","DOI":"10.34133\/cbsystems.0043","article-title":"Bioprinting methods for fabricating In vitro tubular blood vessel models","volume":"4","author":"Kim","year":"2023","journal-title":"Cyborg Bionic Syst."},{"key":"bfad8034bib28","doi-asserted-by":"publisher","DOI":"10.1016\/j.matdes.2023.111885","article-title":"Recent advances in biofabrication strategies based on bioprinting for vascularized tissue repair and regeneration","volume":"229","author":"Xing","year":"2023","journal-title":"Mater. Des."},{"key":"bfad8034bib29","doi-asserted-by":"publisher","first-page":"910","DOI":"10.5114\/aoms.2016.63743","article-title":"2D and 3D cell cultures\u2013a comparison of different types of cancer cell cultures","volume":"14","author":"Kapa\u0142czy\u0144ska","year":"2018","journal-title":"Arch. Med. Sci."},{"key":"bfad8034bib30","doi-asserted-by":"publisher","first-page":"33","DOI":"10.3389\/fmolb.2020.00033","article-title":"Is it time to start transitioning from 2D to 3D cell culture?","volume":"7","author":"Jensen","year":"2020","journal-title":"Front. Mol. Biosci."},{"key":"bfad8034bib31","doi-asserted-by":"publisher","DOI":"10.34133\/2021\/1532103","article-title":"Challenges and possibilities of cell-based tissue-engineered vascular grafts","volume":"2021","author":"Saito","year":"2021","journal-title":"Cyborg Bionic Syst."},{"key":"bfad8034bib32","doi-asserted-by":"publisher","DOI":"10.1002\/adbi.202200041","article-title":"In vitro models of blood and lymphatic vessels\u2014connecting tissues and immunity","volume":"7","author":"Bogseth","year":"2023","journal-title":"Adv. Biol."},{"key":"bfad8034bib33","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201801102","article-title":"Coaxial cell printing of freestanding, perfusable, and functional In vitro vascular models for recapitulation of native vascular endothelium pathophysiology","volume":"7","author":"Gao","year":"2018","journal-title":"Adv. Healthcare Mater."},{"key":"bfad8034bib34","doi-asserted-by":"publisher","first-page":"1856","DOI":"10.1039\/c0lc00651c","article-title":"Production of reactive oxygen species in endothelial cells under different pulsatile shear stresses and glucose concentrations","volume":"11","author":"Chin","year":"2011","journal-title":"Lab Chip"},{"key":"bfad8034bib35","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1039\/C8LC00130H","article-title":"Flow dynamics control endothelial permeability in a microfluidic vessel bifurcation model","volume":"18","author":"Akbari","year":"2018","journal-title":"Lab Chip"},{"key":"bfad8034bib36","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.790529","article-title":"Recent progress in In vitro models for atherosclerosis studies","volume":"8","author":"Chen","year":"2022","journal-title":"Front. Cardiovascular Med."},{"key":"bfad8034bib37","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2021.721843","article-title":"Vascular tissue engineering: challenges and requirements for an ideal large scale blood vessel","volume":"9","author":"Devillard","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"key":"bfad8034bib38","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201900742","article-title":"Fabrication techniques for vascular and vascularized tissue engineering","volume":"8","author":"Wang","year":"2019","journal-title":"Adv. Healthcare Mater."},{"key":"bfad8034bib39","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202100798","article-title":"In vitro strategies to vascularize 3D physiologically relevant models","volume":"8","author":"Dellaquila","year":"2021","journal-title":"Adv. Sci."},{"key":"bfad8034bib40","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.addr.2018.06.007","article-title":"Advanced In vitro models of vascular biology: human induced pluripotent stem cells and organ-on-chip technology","volume":"140","author":"Cochrane","year":"2019","journal-title":"Adv. Drug Deliv. Rev."},{"key":"bfad8034bib41","doi-asserted-by":"publisher","first-page":"7837","DOI":"10.3390\/ijms22157837","article-title":"Tissue-specific decellularized extracellular matrix bioinks for musculoskeletal tissue regeneration and modeling using 3D bioprinting technology","volume":"22","author":"Park","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"bfad8034bib42","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.3390\/pharmaceutics13091373","article-title":"3D printing of pharmaceutical application: drug screening and drug delivery","volume":"13","author":"Gao","year":"2021","journal-title":"Pharmaceutics"},{"key":"bfad8034bib43","doi-asserted-by":"publisher","DOI":"10.1063\/5.0087345","article-title":"3D bioprinted In vitro secondary hyperoxaluria model by mimicking intestinal-oxalate-malabsorption-related kidney stone disease","volume":"9","author":"Yoon","year":"2022","journal-title":"Appl. Phys. Rev."},{"key":"bfad8034bib44","doi-asserted-by":"publisher","DOI":"10.1063\/1.5099306","article-title":"Tissue-engineering of vascular grafts containing endothelium and smooth-muscle using triple-coaxial cell printing","volume":"6","author":"Gao","year":"2019","journal-title":"Appl. Phys. Rev."},{"key":"bfad8034bib45","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201801019","article-title":"3D cell printing of perfusable vascularized human skin equivalent composed of epidermis, dermis, and hypodermis for better structural recapitulation of native skin","volume":"8","author":"Kim","year":"2019","journal-title":"Adv. Healthcare Mater."},{"key":"bfad8034bib46","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201700798","article-title":"Tissue engineered bio\u2010blood\u2010vessels constructed using a tissue\u2010specific bioink and 3D coaxial cell printing technique: a novel therapy for ischemic disease","volume":"27","author":"Gao","year":"2017","journal-title":"Adv. Funct. Mater."},{"key":"bfad8034bib47","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.biomaterials.2016.11.031","article-title":"Skin integrated with perfusable vascular channels on a chip","volume":"116","author":"Mori","year":"2017","journal-title":"Biomaterials"},{"key":"bfad8034bib48","doi-asserted-by":"publisher","first-page":"2686","DOI":"10.1039\/C8LC00285A","article-title":"Microfluidic-based vascularized microphysiological systems","volume":"18","author":"Lee","year":"2018","journal-title":"Lab Chip"},{"key":"bfad8034bib49","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1007\/s10439-005-8760-6","article-title":"Correlation of hemodynamic events with clinical and pathological observations","volume":"33","author":"Lieber","year":"2005","journal-title":"Ann. Biomed. Eng."},{"key":"bfad8034bib50","doi-asserted-by":"publisher","first-page":"3568","DOI":"10.1007\/s10439-016-1663-x","article-title":"The importance of hemorheology and patient anatomy on the hemodynamics in the inferior vena cava","volume":"44","author":"Aycock","year":"2016","journal-title":"Ann. Biomed. Eng."},{"key":"bfad8034bib51","doi-asserted-by":"publisher","DOI":"10.1063\/1.5058242","article-title":"Ground tunnel as renewable energy utilization of ground energy as a source and sink for building heating and cooling","volume":"2018","author":"Hasan","year":"2018","journal-title":"AIP Conf. Proc."},{"key":"bfad8034bib52","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.rcl.2010.02.006","article-title":"CT angiography: current technology and clinical use","volume":"48","author":"Kumamaru","year":"2010","journal-title":"Clin. Radiol."},{"key":"bfad8034bib53","first-page":"p 1833","article-title":"3T intravascular MRI, IVUS and OCT: a study in contrast","author":"Hegde","year":"2013"},{"key":"bfad8034bib54","doi-asserted-by":"publisher","first-page":"119","DOI":"10.3389\/fcvm.2020.00119","article-title":"Advances in IVUS\/OCT and future clinical perspective of novel hybrid catheter system in coronary imaging","volume":"7","author":"Ono","year":"2020","journal-title":"Front. Cardiovascular Med."},{"key":"bfad8034bib55","doi-asserted-by":"publisher","first-page":"671","DOI":"10.3389\/fbioe.2022.855791","article-title":"Medical image-based computational fluid dynamics and fluid-structure interaction analysis in vascular diseases","volume":"10","author":"He","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"key":"bfad8034bib56","doi-asserted-by":"publisher","DOI":"10.1016\/j.imu.2020.100314","article-title":"Computational analysis of the coronary artery hemodynamics with different anatomical variations","volume":"19","author":"Rabbi","year":"2020","journal-title":"Inf. Med. Unlocked"},{"key":"bfad8034bib57","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2022.107007","article-title":"Predicting hemodynamic indices in coronary artery aneurysms using response surface method: an application in Kawasaki disease","volume":"224","author":"Asadbeygi","year":"2022","journal-title":"Comput. Methods Programs Biomed."},{"key":"bfad8034bib58","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1007\/s11831-017-9246-z","article-title":"Review of patient-specific vascular modeling: template-based isogeometric framework and the case for CAD","volume":"26","author":"Urick","year":"2019","journal-title":"Arch. Comput. Methods Eng."},{"key":"bfad8034bib59","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20180309","article-title":"Emerging techniques in atherosclerosis imaging","volume":"92","author":"Syed","year":"2019","journal-title":"Brit. J. Radiol."},{"key":"bfad8034bib60","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1109\/RBME.2020.3011182","article-title":"Simulation of blood as fluid: a review from rheological aspects","volume":"14","author":"Kannojiya","year":"2020","journal-title":"IEEE Rev. Biomed. Eng."},{"key":"bfad8034bib61","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcp.2019.109130","article-title":"A stable high-order FC-based methodology for hemodynamic wave propagation","volume":"405","author":"Amlani","year":"2020","journal-title":"J. Comput. Phys."},{"key":"bfad8034bib62","doi-asserted-by":"publisher","first-page":"272","DOI":"10.3390\/bioengineering10020272","article-title":"The effect of blood rheology and inlet boundary conditions on realistic abdominal aortic aneurysms under pulsatile flow conditions","volume":"10","author":"Tzirakis","year":"2023","journal-title":"Bioengineering"},{"key":"bfad8034bib63","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12938-018-0497-1","article-title":"The effect of inlet and outlet boundary conditions in image-based CFD modeling of aortic flow","volume":"17","author":"Madhavan","year":"2018","journal-title":"Biomed. Eng. Online"},{"key":"bfad8034bib64","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1007\/s42452-019-0737-4","article-title":"Atherosclerosis research: the impact of physiological parameters on vascular wall stress","volume":"1","author":"Lu","year":"2019","journal-title":"SN Appl. Sci."},{"key":"bfad8034bib65","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.ijmecsci.2018.10.046","article-title":"Numerical solution of the Pulsatile, non-Newtonian and turbulent blood flow in a patient specific elastic carotid artery","volume":"150","author":"Moradicheghamahi","year":"2019","journal-title":"Int. J. Mech. Sci."},{"key":"bfad8034bib66","doi-asserted-by":"publisher","DOI":"10.3389\/fmedt.2021.748908","article-title":"On the role and effects of uncertainties in cardiovascular in silico analyses","volume":"3","author":"Celi","year":"2021","journal-title":"Front. Med. Technol."},{"key":"bfad8034bib67","article-title":"Comparison of CFD and FSI simulations of blood flow in stenotic coronary arteries, applications of computational fluid dynamics simulation and modeling","author":"Carvalho","year":"2022"},{"key":"bfad8034bib68","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2023.1304278","article-title":"Characterizing atherosclerotic tissues: in silico analysis of mechanical properties using intravascular ultrasound and inverse finite element methods","volume":"11","author":"Latorre","year":"2023","journal-title":"Front. Bioeng. Biotechnol."},{"key":"bfad8034bib69","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.icheatmasstransfer.2015.06.017","article-title":"A parametric model for analysing atherosclerotic arteries: on the FSI coupling","volume":"67","author":"Cilla","year":"2015","journal-title":"Int. J. Heat Mass Transfer"},{"key":"bfad8034bib70","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.1161\/CIRCULATIONAHA.105.603050","article-title":"Evidence of a dominant backward-propagating \u201csuction\u201d wave responsible for diastolic coronary filling in humans, attenuated in left ventricular hypertrophy","volume":"113","author":"Davies","year":"2006","journal-title":"Circulation"},{"key":"bfad8034bib71","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1016\/j.jbiomech.2013.11.007","article-title":"Higher critical plaque wall stress in patients who died of coronary artery disease compared with those who died of other causes: a 3D FSI study based on ex vivo MRI of coronary plaques","volume":"47","author":"Huang","year":"2014","journal-title":"J. Biomech."},{"key":"bfad8034bib72","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2021.106148","article-title":"FSI modeling on the effect of artery-aneurysm thickness and coil embolization in patient cases","volume":"206","author":"Paz","year":"2021","journal-title":"Comput. Methods Programs Biomed."},{"key":"bfad8034bib73","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-75362-5","article-title":"Prediction of rupture risk in cerebral aneurysms by comparing clinical cases with fluid\u2013structure interaction analyses","volume":"10","author":"Cho","year":"2020","journal-title":"Sci. Rep."},{"key":"bfad8034bib74","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2023.107178","article-title":"On the major role played by the lumen curvature of intracranial aneurysms walls in determining their mechanical response, local hemodynamics, and rupture likelihood","volume":"163","author":"Oliveira","year":"2023","journal-title":"Comput. Biol. Med."},{"key":"bfad8034bib75","doi-asserted-by":"publisher","first-page":"269","DOI":"10.3390\/bioengineering11030269","article-title":"Analysis of intracranial aneurysm haemodynamics altered by wall movement","volume":"11","author":"Goetz","year":"2024","journal-title":"Bioengineering"},{"key":"bfad8034bib76","doi-asserted-by":"publisher","first-page":"2484","DOI":"10.1007\/s10439-020-02543-8","article-title":"In vitro assessment of flow variability in an intracranial aneurysm model using 4D flow MRI and tomographic PIV","volume":"48","author":"Medero","year":"2020","journal-title":"Ann. Biomed. Eng."},{"key":"bfad8034bib77","doi-asserted-by":"publisher","first-page":"277","DOI":"10.3390\/fluids6080277","article-title":"Comparison of four-dimensional flow magnetic resonance imaging and particle image velocimetry to quantify velocity and turbulence parameters","volume":"6","author":"Kim","year":"2021","journal-title":"Fluids"},{"key":"bfad8034bib78","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s13239-021-00583-2","article-title":"Hemodynamic study of a patient-specific intracranial aneurysm: comparative assessment of tomographic PIV, stereoscopic PIV, in vivo MRI and computational fluid dynamics","volume":"13","author":"Wu","year":"2022","journal-title":"Cardiovascular Eng. Technol."},{"key":"bfad8034bib79","doi-asserted-by":"publisher","DOI":"10.1016\/j.inat.2020.100716","article-title":"A review of hemodynamic parameters in cerebral aneurysm","volume":"22","author":"Sheikh","year":"2020","journal-title":"Interdiscip. Neurosurg."},{"key":"bfad8034bib80","doi-asserted-by":"publisher","first-page":"1657","DOI":"10.47176\/jafm.14.06.32319","article-title":"Wall shear stress-based hemodynamic descriptors in the abdominal aorta bifurcation: analysis of a case study","volume":"14","author":"Soares","year":"2021","journal-title":"J. Appl. Fluid Mech."},{"key":"bfad8034bib81","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1083547","article-title":"Wall shear stress and its role in atherosclerosis","volume":"10","author":"Zhou","year":"2023","journal-title":"Front. Cardiovascular Med."},{"key":"bfad8034bib82","first-page":"7","article-title":"Three-dimensional reconstruction and hemodynamic analysis of varicose veins in lower extremities based on ABUS image","author":"Cai","year":"2022"},{"key":"bfad8034bib83","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1093\/neuros\/nyx433","article-title":"Influence of relative residence time on side-wall aneurysm inception","volume":"83","author":"Riccardello","year":"2018","journal-title":"Neurosurgery"},{"key":"bfad8034bib84","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/j.avsg.2019.04.032","article-title":"Computational fluid dynamics modeling of hemodynamic parameters in the human diseased aorta: a systematic review","volume":"63","author":"Ong","year":"2020","journal-title":"Ann. Vasc. Surg."},{"key":"bfad8034bib85","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2023.1159288","article-title":"Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques","volume":"14","author":"He","year":"2023","journal-title":"Front. Neurol."},{"key":"bfad8034bib86","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.medengphy.2019.09.010","article-title":"Multivariate analysis of hemodynamic parameters on intracranial aneurysm initiation of the internal carotid artery","volume":"74","author":"Sunderland","year":"2019","journal-title":"Med. Eng. Phys."},{"key":"bfad8034bib87","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1007\/s10439-012-0695-0","article-title":"High wall shear stress and spatial gradients in vascular pathology: a review","volume":"41","author":"Dolan","year":"2013","journal-title":"Ann. Biomed. Eng."},{"key":"bfad8034bib88","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2019.103453","article-title":"Patient specific characterization of artery and plaque material properties in peripheral artery disease","volume":"101","author":"Noble","year":"2020","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"bfad8034bib89","doi-asserted-by":"publisher","first-page":"708","DOI":"10.3390\/bioengineering9110708","article-title":"Influence of rigid\u2013elastic artery wall of carotid and coronary stenosis on hemodynamics","volume":"9","author":"Albadawi","year":"2022","journal-title":"Bioengineering"},{"key":"bfad8034bib90","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.ijmecsci.2019.06.029","article-title":"Influence of arterial mechanical properties on carotid blood flow: comparison of CFD and FSI studies","volume":"160","author":"Lopes","year":"2019","journal-title":"Int. J. Mech. Sci."},{"key":"bfad8034bib91","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1016\/j.compstruc.2006.08.041","article-title":"Compliant biomechanics of abdominal aortic aneurysms: a fluid\u2013structure interaction study","volume":"85","author":"Scotti","year":"2007","journal-title":"Comput. Struct."},{"key":"bfad8034bib92","doi-asserted-by":"publisher","first-page":"43","DOI":"10.3389\/fsurg.2016.00043","article-title":"Biology of saccular cerebral aneurysms: a review of current understanding and future directions","volume":"3","author":"Fennell","year":"2016","journal-title":"Front. Surg."},{"key":"bfad8034bib93","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.jbiomech.2015.10.047","article-title":"Endothelialization of over-and undersized flow-diverter stents at covered vessel side branches: an in vivo and in silico study","volume":"49","author":"Berg","year":"2016","journal-title":"J. Biomech."},{"key":"bfad8034bib94","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1111\/pin.13202","article-title":"Atherosclerosis: known and unknown","volume":"72","author":"Fan","year":"2022","journal-title":"Pathol. Int."},{"key":"bfad8034bib95","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41569-022-00803-9","article-title":"Flow-induced reprogramming of endothelial cells in atherosclerosis","volume":"20","author":"Tamargo","year":"2023","journal-title":"Nat. Rev. Cardiol."},{"key":"bfad8034bib96","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202008878","article-title":"Construction of a novel In vitro atherosclerotic model from geometry\u2010tunable artery equivalents engineered via in\u2010bath coaxial cell printing","volume":"31","author":"Gao","year":"2021","journal-title":"Adv. Funct. Mater."},{"key":"bfad8034bib97","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2021.828577","article-title":"The correlation between wall shear stress and plaque composition in advanced human carotid atherosclerosis","volume":"9","author":"Moerman","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"key":"bfad8034bib98","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1038\/s42003-022-04014-3","article-title":"Angular difference in human coronary artery governs endothelial cell structure and function","volume":"5","author":"Katakia","year":"2022","journal-title":"Commun. Biol."},{"key":"bfad8034bib99","doi-asserted-by":"publisher","DOI":"10.1088\/1758-5090\/aceffa","article-title":"Sequentially suspended 3D bioprinting of multiple-layered vascular models with tunable geometries for In vitro modeling of arterial disorders initiation","volume":"15","author":"Pan","year":"2023","journal-title":"Biofabrication"},{"key":"bfad8034bib100","doi-asserted-by":"publisher","first-page":"454","DOI":"10.3389\/fphys.2020.00454","article-title":"Computational hemodynamic modeling of arterial aneurysms: a mini-review","volume":"11","author":"Lipp","year":"2020","journal-title":"Front. Physiol."},{"key":"bfad8034bib101","doi-asserted-by":"publisher","first-page":"3613","DOI":"10.1161\/STROKEAHA.113.002390","article-title":"Review of cerebral aneurysm formation, growth, and rupture","volume":"44","author":"Chalouhi","year":"2013","journal-title":"Stroke"},{"key":"bfad8034bib102","doi-asserted-by":"publisher","DOI":"10.1016\/j.patter.2023.100709","article-title":"A deep-learning method for the end-to-end prediction of intracranial aneurysm rupture risk","volume":"4","author":"Li","year":"2023","journal-title":"Patterns"},{"key":"bfad8034bib103","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.wneu.2019.07.093","article-title":"Aneurysm formation, growth, and rupture: the biology and physics of cerebral aneurysms","volume":"130","author":"Texakalidis","year":"2019","journal-title":"World Neurosurg."},{"key":"bfad8034bib104","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1186\/s41016-021-00260-2","article-title":"Underlying mechanism of hemodynamics and intracranial aneurysm","volume":"8","author":"Tang","year":"2022","journal-title":"Chin. Neurosurg. J."},{"key":"bfad8034bib105","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1007\/s12975-013-0290-1","article-title":"Vascular smooth muscle cells in cerebral aneurysm pathogenesis","volume":"5","author":"Starke","year":"2014","journal-title":"Transl. Stroke Res."},{"key":"bfad8034bib106","doi-asserted-by":"publisher","first-page":"E21","DOI":"10.3171\/2019.5.FOCUS19234","article-title":"Flow-induced, inflammation-mediated arterial wall remodeling in the formation and progression of intracranial aneurysms","volume":"47","author":"Fr\u00f6sen","year":"2019","journal-title":"Neurosurg. Focus"},{"key":"bfad8034bib107","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-14279-7","article-title":"Patient-specific brain arteries molded as a flexible phantom model using 3D printed water-soluble resin","volume":"12","author":"Nilsson","year":"2022","journal-title":"Sci. Rep."},{"key":"bfad8034bib108","doi-asserted-by":"publisher","DOI":"10.1038\/srep44301","article-title":"Fabrication of cerebral aneurysm simulator with a desktop 3D printer","volume":"7","author":"Liu","year":"2017","journal-title":"Sci. Rep."},{"key":"bfad8034bib109","doi-asserted-by":"publisher","DOI":"10.1115\/1.4054981","article-title":"Endothelial responses to curvature-induced flow patterns in engineered cerebral aneurysms","volume":"145","author":"Mandrycky","year":"2023","journal-title":"J. Biomech. Eng."},{"key":"bfad8034bib110","doi-asserted-by":"publisher","DOI":"10.1088\/1758-5090\/abbb9b","article-title":"Three-dimensional bioprinting of aneurysm-bearing tissue structure for endovascular deployment of embolization coils","volume":"13","author":"Jang","year":"2020","journal-title":"Biofabrication"},{"key":"bfad8034bib111","doi-asserted-by":"publisher","DOI":"10.1038\/srep12401","article-title":"Do-it-yourself In vitro vasculature that recapitulates in vivo geometries for investigating endothelial-blood cell interactions","volume":"5","author":"Mannino","year":"2015","journal-title":"Sci. Rep."},{"key":"bfad8034bib112","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.732561","article-title":"Fully-coupled FSI computational analyses in the ascending thoracic aorta using patient-specific conditions and anisotropic material properties","volume":"12","author":"Vignali","year":"2021","journal-title":"Front. Physiol."},{"key":"bfad8034bib113","doi-asserted-by":"publisher","first-page":"107","DOI":"10.5469\/neuroint.2023.00164","article-title":"The current limitations and advanced analysis of hemodynamic study of cerebral aneurysms","volume":"18","author":"Cho","year":"2023","journal-title":"Neurointervention"},{"key":"bfad8034bib114","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.3174\/ajnr.A3558","article-title":"High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis","volume":"35","author":"Meng","year":"2014","journal-title":"Am. J. Neuroradiol."},{"key":"bfad8034bib115","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1007\/s10143-021-01672-5","article-title":"Intracranial aneurysm wall (in) stability\u2013current state of knowledge and clinical perspectives","volume":"45","author":"Morel","year":"2022","journal-title":"Neurosurg. Rev."},{"key":"bfad8034bib116","doi-asserted-by":"publisher","DOI":"10.1177\/20503121221118992","article-title":"Global impact and contributing factors in varicose vein disease development","volume":"10","author":"Aslam","year":"2022","journal-title":"SAGE Open Med."},{"key":"bfad8034bib117","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1016\/j.jval.2018.01.012","article-title":"Cost-effectiveness of current and emerging treatments of varicose veins","volume":"21","author":"Epstein","year":"2018","journal-title":"Value Health"},{"key":"bfad8034bib118","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2012\/538627","article-title":"Varicose veins: role of mechanotransduction of venous hypertension","volume":"2012","author":"Atta","year":"2012","journal-title":"Int. J. Vasc. Med."},{"key":"bfad8034bib119","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/s12551-021-00783-z","article-title":"Role of mechanosignaling on pathology of varicose vein","volume":"13","author":"Saberianpour","year":"2021","journal-title":"Biophys. Rev."},{"key":"bfad8034bib120","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1016\/j.jvs.2009.06.048","article-title":"In vitro differences between smooth muscle cells derived from varicose veins and normal veins","volume":"50","author":"Xiao","year":"2009","journal-title":"J. Vasc. Surg."},{"key":"bfad8034bib121","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1016\/j.ijbiomac.2022.11.064","article-title":"Bioengineering strategies for 3D bioprinting of tubular construct using tissue-specific decellularized extracellular matrix","volume":"223","author":"Kamaraj","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"bfad8034bib122","doi-asserted-by":"publisher","first-page":"3563","DOI":"10.3390\/cells10123563","article-title":"Shear stress alterations activate BMP4\/pSMAD5 signaling and induce endothelial mesenchymal transition in varicose veins","volume":"10","author":"Chandran Latha","year":"2021","journal-title":"Cells"},{"key":"bfad8034bib123","doi-asserted-by":"publisher","first-page":"109","DOI":"10.3389\/fbioe.2019.00109","article-title":"Physical vein models to quantify the flow performance of sclerosing foams","volume":"7","author":"Bottaro","year":"2019","journal-title":"Front. Bioeng. Biotechnol."},{"key":"bfad8034bib124","doi-asserted-by":"publisher","first-page":"169","DOI":"10.34172\/bi.2020.21","article-title":"Fluid-structure interaction of blood flow around a vein valve","volume":"10","author":"Hajati","year":"2020","journal-title":"Bioimpacts"},{"key":"bfad8034bib125","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1177\/1708538115594095","article-title":"A computational fluid\u2013structure interaction model of the blood flow in the healthy and varicose saphenous vein","volume":"24","author":"Razaghi","year":"2016","journal-title":"Vascular"},{"key":"bfad8034bib126","doi-asserted-by":"publisher","first-page":"59","DOI":"10.3390\/mi9020059","article-title":"Sinusoidal microchannel with descending curves for varicose veins implantation","volume":"9","author":"Afzal","year":"2018","journal-title":"Micromachines"},{"key":"bfad8034bib127","doi-asserted-by":"publisher","first-page":"141","DOI":"10.3389\/fcvm.2019.00141","article-title":"Shear-dependent platelet aggregation: mechanisms and therapeutic opportunities","volume":"6","author":"Rana","year":"2019","journal-title":"Front. Cardiovascular Med."},{"key":"bfad8034bib128","doi-asserted-by":"publisher","first-page":"9342","DOI":"10.1073\/pnas.1201240109","article-title":"In vitro microvessels for the study of angiogenesis and thrombosis","volume":"109","author":"Zheng","year":"2012","journal-title":"Proc. Natl Acad. Sci."},{"key":"bfad8034bib129","doi-asserted-by":"publisher","first-page":"4097","DOI":"10.1039\/C6LC00380J","article-title":"Bioprinted thrombosis-on-a-chip","volume":"16","author":"Zhang","year":"2016","journal-title":"Lab Chip"},{"key":"bfad8034bib130","doi-asserted-by":"publisher","first-page":"0048","DOI":"10.34133\/research.0048","article-title":"A model of high-speed endovascular sonothrombolysis with vortex ultrasound-induced shear stress to treat cerebral venous sinus thrombosis","volume":"6","author":"Zhang","year":"2023","journal-title":"Research"},{"key":"bfad8034bib131","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiolchem.2019.107148","article-title":"Recent advances in computational modeling of fibrin clot formation: a review","volume":"83","author":"Yesudasan","year":"2019","journal-title":"Comput. Biol. Chem."},{"key":"bfad8034bib132","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2021.110349","article-title":"Mechanobiology of shear-induced platelet aggregation leading to occlusive arterial thrombosis: a multiscale in silico analysis","volume":"120","author":"Liu","year":"2021","journal-title":"J. Biomech."},{"key":"bfad8034bib133","doi-asserted-by":"publisher","first-page":"2785","DOI":"10.1039\/C7LC00202E","article-title":"Mimicking arterial thrombosis in a 3D-printed microfluidic In vitro vascular model based on computed tomography angiography data","volume":"17","author":"Costa","year":"2017","journal-title":"Lab Chip"},{"key":"bfad8034bib134","doi-asserted-by":"publisher","DOI":"10.1098\/rsfs.2019.0126","article-title":"Haemodynamic flow conditions at the initiation of high-shear platelet aggregation: a combined In vitro and cellular in silico study","volume":"11","author":"Van Rooij","year":"2021","journal-title":"Interface Focus"},{"key":"bfad8034bib135","doi-asserted-by":"publisher","first-page":"5426","DOI":"10.1038\/s41467-020-19197-8","article-title":"Modeling early stage atherosclerosis in a primary human vascular microphysiological system","volume":"11","author":"Zhang","year":"2020","journal-title":"Nat. Commun."},{"key":"bfad8034bib136","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnonlinmec.2022.104275","article-title":"Hyperelastic structures: a review on the mechanics and biomechanics","volume":"148","author":"Khaniki","year":"2023","journal-title":"Int. J. Non-Linear Mech."},{"key":"bfad8034bib137","doi-asserted-by":"publisher","first-page":"59103","DOI":"10.1021\/acsami.3c07756","article-title":"Endothelial response to the combined biomechanics of vessel stiffness and shear stress is regulated via Piezo1","volume":"15","author":"Lai","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"bfad8034bib138","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1161\/CIRCRESAHA.121.319984","article-title":"Bioengineering human tissues and the future of vascular replacement","volume":"131","author":"Naegeli","year":"2022","journal-title":"Circ. Res."},{"key":"bfad8034bib139","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s13239-023-00671-5","article-title":"Preclinical models of cardiac disease: a comprehensive overview for clinical scientists","volume":"15","author":"van Doorn","year":"2024","journal-title":"Cardiovascular Eng. Technol."},{"key":"bfad8034bib140","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1007\/s10439-017-1806-8","article-title":"Stents: biomechanics, biomaterials, and insights from computational modeling","volume":"45","author":"Karanasiou","year":"2017","journal-title":"Ann. Biomed. Eng."},{"key":"bfad8034bib141","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1093\/eurheartj\/ehv689","article-title":"Biomechanical stress in coronary atherosclerosis: emerging insights from computational modelling","volume":"38","author":"Thondapu","year":"2017","journal-title":"Eur. Heart J."},{"key":"bfad8034bib142","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2022.105325","article-title":"Computational analysis of the role of mechanosensitive Notch signaling in arterial adaptation to hypertension","volume":"133","author":"van Asten","year":"2022","journal-title":"J. Mech. Behav. Biomed. Mater."}],"container-title":["Biofabrication"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1758-5090\/ad8034","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1758-5090\/ad8034\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1758-5090\/ad8034","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1758-5090\/ad8034\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1758-5090\/ad8034\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1758-5090\/ad8034\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1758-5090\/ad8034\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1758-5090\/ad8034\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T05:20:36Z","timestamp":1729747236000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1758-5090\/ad8034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,24]]},"references-count":142,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,10,24]]},"published-print":{"date-parts":[[2025,1,1]]}},"URL":"https:\/\/doi.org\/10.1088\/1758-5090\/ad8034","relation":{},"ISSN":["1758-5082","1758-5090"],"issn-type":[{"value":"1758-5082","type":"print"},{"value":"1758-5090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,24]]},"assertion":[{"value":"3D engineering of diseased blood vessels for integrative in vitro\u2013in silico mechanobiology study","name":"article_title","label":"Article Title"},{"value":"Biofabrication","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2024 IOP Publishing Ltd. All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2024-02-28","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-09-26","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-10-24","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}