{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T16:15:03Z","timestamp":1788970503054,"version":"build-2803163510"},"reference-count":71,"publisher":"IOP Publishing","issue":"2","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/publishingsupport.iopscience.iop.org\/iop-standard\/v1"},{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Med. Eng. Phys."],"published-print":{"date-parts":[[2026,2,2]]},"DOI":"10.1088\/1873-4030\/ae28ed","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T11:57:25Z","timestamp":1768910245000},"page":"025006","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Mechanical behavior of nerve roots and pain mechanisms: insights and opportunities for advancement"],"prefix":"10.1088","volume":"147","author":[{"given":"Mackenzie","family":"Hoey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel Bruns","family":"Estorge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlin","family":"Gallagher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Vadati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zac","family":"Domire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"mepae28edbib1","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.clinbiomech.2016.02.014","type":"journal-article","article-title":"Decreased neck muscle strength in patients with the loss of cervical lordosis","volume":"33","author":"Alpayci","year":"2016","journal-title":"Clin. Biomech."},{"key":"mepae28edbib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbiomech.2022.111416","type":"journal-article","article-title":"Head supported mass, moment of inertia, neck loads and stability: a simulation study","volume":"146","author":"Barrett","year":"2023","journal-title":"J. Biomech."},{"key":"mepae28edbib3","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/0021-9290(84)90009-5","type":"journal-article","article-title":"Alterations in the mechanical properties of peripheral nerve following crush injury","volume":"17","author":"Beel","year":"1984","journal-title":"J. Biomech."},{"key":"mepae28edbib4","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/0014-4886(86)90023-3","type":"journal-article","article-title":"Structural properties of spinal nerve roots: biomechanics","volume":"91","author":"Beel","year":"1986","journal-title":"Exp. Neurol."},{"key":"mepae28edbib5","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1007\/s00415-016-8204-2","type":"journal-article","article-title":"Proximal nerve lesions in early Guillain\u2013Barr\u00e9 syndrome: implications for pathogenesis and disease classification","volume":"264","author":"Berciano","year":"2017","journal-title":"J. Neurol."},{"key":"mepae28edbib6","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1056\/NEJMCP043887","type":"journal-article","article-title":"Clinical practice. Cervical radiculopathy","volume":"353","author":"Carette","year":"2005","journal-title":"New Engl. J. Med."},{"key":"mepae28edbib7","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1007\/s11420-011-9218-z","type":"journal-article","article-title":"Cervical radiculopathy: a review","volume":"7","author":"Caridi","year":"2011","journal-title":"HSS J. Musculoskelet. J. Hosp. Spec. Surg."},{"key":"mepae28edbib8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.pmr.2010.10.001","type":"journal-article","article-title":"Natural history of radiculopathy","volume":"22","author":"Casey","year":"2011","journal-title":"Phys. Med. Rehabil. Clin."},{"key":"mepae28edbib9","doi-asserted-by":"publisher","DOI":"10.2174\/1573405620666230612122725","type":"journal-article","article-title":"Application of magnetic resonance diffusion tensor imaging in diagnosis of lumbosacral nerve root compression","volume":"20","author":"Cheng","year":"2024","journal-title":"Curr. Med. Imaging"},{"key":"mepae28edbib10","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1097\/00007632-199705010-00003","type":"journal-article","article-title":"A model for chronic nerve root compression studies: presentation of a porcine model for controlled, slow-onset compression with analyses of anatomic aspects, compression onset rate, and morphologic and neurophysiologic effects","volume":"22","author":"Cornefjord","year":"1997","journal-title":"Spine"},{"key":"mepae28edbib11","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1016\/j.spinee.2017.03.009","type":"journal-article","article-title":"\u201cText neck\u201d: an epidemic of the modern era of cell phones?","volume":"17","author":"Cu\u00e9llar","year":"2017","journal-title":"Spine J."},{"key":"mepae28edbib12","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1007\/BF02337826","type":"journal-article","article-title":"Biomechanics of the lumbar spinal nerve roots and the first sacral root within the intervertebral foramina","volume":"11","author":"De Peretti","year":"1989","journal-title":"Radiol. Anat. J. Clin. Anat."},{"key":"mepae28edbib13","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1177\/0269215511419536","type":"journal-article","article-title":"The efficacy of forward head correction on nerve root function and pain in cervical spondylotic radiculopathy: a randomized trial","volume":"26","author":"Diab","year":"2012","journal-title":"Clin. Rehabil."},{"key":"mepae28edbib14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.clinbiomech.2008.09.010","type":"journal-article","article-title":"Intervertebral neural foramina deformation due to two types of repetitive combined loading","volume":"24","author":"Drake","year":"2009","journal-title":"Clin. Biomech."},{"key":"mepae28edbib15","doi-asserted-by":"publisher","first-page":"2245","DOI":"10.1089\/neu.2009.0973","type":"journal-article","article-title":"An in-vitro traumatic model to evaluate the response of myelinated cultures to sustained hydrostatic compression injury","volume":"26","author":"Frieboes","year":"2009","journal-title":"J. Neurotrauma"},{"key":"mepae28edbib16","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1053\/j.semss.2015.11.009","type":"journal-article","article-title":"Epidemiology and pathophysiology of cervical disc herniation","volume":"28","author":"Hammer","year":"2016","journal-title":"Semin. Spine Surg."},{"key":"mepae28edbib17","first-page":"277","type":"journal-article","article-title":"Assessment of stresses in the cervical spine caused by posture and position of the head","volume":"25","author":"Hansraj","year":"2014","journal-title":"Surg. Technol. Int."},{"key":"mepae28edbib18","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1016\/S0161-4754(99)70086-2","type":"journal-article","article-title":"A review of biomechanics of the central nervous system\u2014part III: spinal cord stresses from postural loads and their neurologic effects","volume":"22","author":"Harrison","year":"1999","journal-title":"J. Manipulative Physiol. Ther."},{"key":"mepae28edbib19","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1097\/00007632-198301000-00010","type":"journal-article","article-title":"Anatomic study of the interrelation between lumbosacral nerve roots and their surrounding tissues","volume":"8","author":"Hasue","year":"1983","journal-title":"Spine"},{"key":"mepae28edbib20","doi-asserted-by":"publisher","first-page":"1924","DOI":"10.1097\/01.brs.0000176239.72928.00","type":"journal-article","article-title":"Transient cervical nerve root compression in the rat induces bilateral forepaw allodynia and spinal glial activation: mechanical factors in painful neck injuries","volume":"30","author":"Hubbard","year":"2005","journal-title":"Spine"},{"key":"mepae28edbib21","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1016\/s0003-9993(98)90179-4","type":"journal-article","article-title":"Flexion and traction effect on C5-C6 foraminal space","volume":"79","author":"Humphreys","year":"1998","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"mepae28edbib22","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.spinee.2012.12.002","type":"journal-article","article-title":"Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair?","volume":"13","author":"Iatridis","year":"2013","journal-title":"Spine J."},{"key":"mepae28edbib23","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.jnca.2015.05.009","type":"journal-article","article-title":"Pervasive gaming: status, trends and design principles","volume":"55","author":"Kasapakis","year":"2015","journal-title":"J. Netw. Comput. Appl."},{"key":"mepae28edbib24","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1016\/j.clinbiomech.2015.08.013","type":"journal-article","article-title":"Influence of sagittal and axial types of ossification of posterior longitudinal ligament on mechanical stress in cervical spinal cord: a finite element analysis","volume":"30","author":"Khuyagbaatar","year":"2015","journal-title":"Clin. Biomech."},{"key":"mepae28edbib25","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1097\/00007632-198401000-00007","type":"journal-article","article-title":"Anatomic and clinical studies of radicular symptoms","volume":"9","author":"Kikuchi","year":"1984","journal-title":"Spine"},{"key":"mepae28edbib26","doi-asserted-by":"publisher","first-page":"2544","DOI":"10.1097\/00007632-199611150-00003","type":"journal-article","article-title":"Increased resistance to acute compression injury in chronically compressed spinal nerve roots. An experimental study","volume":"21","author":"Kikuchi","year":"1996","journal-title":"Spine"},{"key":"mepae28edbib27","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1080\/00140139.2020.1869320","type":"journal-article","article-title":"User discomfort while using a virtual reality headset as a personal viewing system for text-intensive office tasks","volume":"64","author":"Kim","year":"2021","journal-title":"Ergonomics"},{"key":"mepae28edbib28","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1097\/00024720-200406000-00009","type":"journal-article","article-title":"The course of the nerve root in the neural foramen and its relationship with foraminal entrapment or impingement in adult patients with lumbar isthmic spondylolisthesis and radicular pain","volume":"17","author":"Kim","year":"2004","journal-title":"Spinal Disord. Technol."},{"key":"mepae28edbib29","doi-asserted-by":"publisher","first-page":"E65","DOI":"10.1097\/01.brs.0000252202.85377.96","type":"journal-article","article-title":"Electrophysiologic changes in dorsal root ganglion neurons and behavioral changes in a lumbar radiculopathy model","volume":"32","author":"Kirita","year":"2007","journal-title":"Spine"},{"key":"mepae28edbib30","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1227\/01.NEU.0000347002.67982.8F","type":"journal-article","article-title":"Pathoanatomic basis for stretch-induced lumbar nerve root injury with a review of the literature","volume":"65","author":"Kitab","year":"2009","journal-title":"Neurosurgery"},{"key":"mepae28edbib31","doi-asserted-by":"publisher","DOI":"10.1016\/J.JBIOMECH.2022.111058","type":"journal-article","article-title":"Biomechanical characterization of isolated epineurial and perineurial membranes of rabbit sciatic nerve","volume":"136","author":"Koppaka","year":"2022","journal-title":"J. Biomech."},{"key":"mepae28edbib32","doi-asserted-by":"publisher","first-page":"559","DOI":"10.3357\/ASEM.2935.2011","type":"journal-article","article-title":"Neck pain among fighter pilots after the introduction of the JHMCS helmet and NVG in their environment","volume":"82","author":"Lange","year":"2011","journal-title":"Aviat. Space Environ. Med."},{"key":"mepae28edbib33","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1097\/BRS.0000000000000687","type":"journal-article","article-title":"Young investigator award winner: cervical nerve root displacement and strain during upper limb neural tension testing part 2: role of foraminal ligaments in the cervical spine","volume":"2014","author":"Lohman","year":"2015a","journal-title":"Spine"},{"key":"mepae28edbib34","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1097\/BRS.0000000000000686","type":"journal-article","article-title":"Young investigator award winner: cervical nerve root displacement and strain during upper limb neural tension testing part 1: a minimally invasive assessment in unembalmed cadavers","volume":"2014","author":"Lohman","year":"2015b","journal-title":"Spine"},{"key":"mepae28edbib35","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1302\/0301-620X.55B2.390","type":"journal-article","article-title":"Effects of stretching the tibial nerve of the rabbit. A preliminary study of the intraneural circulation and the barrier function of the perineurium","volume":"55","author":"Lundborg","year":"1973","journal-title":"J. Bone Joint Surg. Br."},{"key":"mepae28edbib36","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1002\/MSC.1498","type":"journal-article","article-title":"Cervical spine radiculopathy epidemiology: a systematic review","volume":"18","author":"Mansfield","year":"2020","journal-title":"Musculoskeletal Care"},{"key":"mepae28edbib37","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1097\/01.brs.0000261030.97483.ac","type":"journal-article","article-title":"Neurophysiologic changes after preganglionic and postganglionic nerve-root constriction: an experimental study in the rat","volume":"32","author":"Matsuda","year":"2007","journal-title":"Spine"},{"key":"mepae28edbib38","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1227\/01.neu.0000163481.58673.1a","type":"journal-article","article-title":"Anatomic analysis of the transforaminal ligament in the lumbar intervertebral foramen","volume":"57","author":"Min","year":"2005","journal-title":"Neurosurgery"},{"key":"mepae28edbib39","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1080\/21577323.2013.840342","type":"journal-article","article-title":"Neck postures and cervical spine loading among microsurgeons operating with loupes and headlamp","volume":"1","author":"Nimbarte","year":"2013","journal-title":"IIE Trans. Occup. Ergon. Hum. Factors"},{"key":"mepae28edbib40","first-page":"1605","type":"journal-article","article-title":"Occult lumbar lateral spinal stenosis in neural foramina subjected to physiologic loading","volume":"17","author":"Nowicki","year":"1996","journal-title":"Am. J. Neuroradiol."},{"key":"mepae28edbib41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3109\/17453679108993081","type":"journal-article","article-title":"Spinal nerve root compression: nutrition and function of the porcine cauda equina compressed in vivo","volume":"62","author":"Olmarker","year":"1991","journal-title":"Acta Orthop. Scand."},{"key":"mepae28edbib42","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1097\/00007632-199005000-00013","type":"journal-article","article-title":"Importance of compression onset rate for the degree of impairment of impulse propagation in experimental compression injury of the porcine cauda equina","volume":"15","author":"Olmarker","year":"1990","journal-title":"Spine"},{"key":"mepae28edbib43","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/S0030-5898(20)31648-5","type":"journal-article","article-title":"Pathophysiology of sciatica","volume":"22","author":"Olmarker","year":"1991","journal-title":"Orthop. Clin. North Am."},{"key":"mepae28edbib44","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1148\/38.2.160","type":"journal-article","article-title":"Calcification and ossification of vertebral ligaments (spondylitis ossificans ligamentosa): roentgen study of pathogenesis and clinical significance","volume":"38","author":"Oppenheimer","year":"1942","journal-title":"Radiology"},{"key":"mepae28edbib45","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1007\/BF02489047","type":"journal-article","article-title":"Tolerance to acute compression injury and recovery of nerve function in chronically compressed spinal nerve roots: experimental study","volume":"2","author":"Otani","year":"1997","journal-title":"J. Orthop. Sci."},{"key":"mepae28edbib46","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/ABCDBE","type":"journal-article","article-title":"Compliant peripheral nerve interfaces","volume":"18","author":"Paggi","year":"2021","journal-title":"J. Neural Eng."},{"key":"mepae28edbib47","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1097\/00007632-199202000-00013","type":"journal-article","article-title":"Effects of magnitude and duration of compression on spinal nerve root conduction","volume":"17","author":"Pedowitz","year":"1992","journal-title":"Spine"},{"key":"mepae28edbib48","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1016\/j.mehy.2011.09.025","type":"journal-article","article-title":"Transforaminal ligament may play a role in lumbar nerve root compression of foraminal stenosis","volume":"77","author":"Qian","year":"2011","journal-title":"Med. Hypotheses"},{"key":"mepae28edbib49","doi-asserted-by":"publisher","DOI":"10.1063\/1.5108867","type":"journal-article","article-title":"Mechanical changes of peripheral nerve tissue microenvironment and their structural basis during development","volume":"3","author":"Rosso","year":"2019","journal-title":"APL Bioeng."},{"key":"mepae28edbib50","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1089\/neu.2009.1045","type":"journal-article","article-title":"Time-dependent mechanics and measures of glial activation and behavioral sensitivity in a rodent model of radiculopathy","volume":"27","author":"Rothman","year":"2010","journal-title":"J. Neurotrauma"},{"key":"mepae28edbib51","first-page":"62","type":"journal-article","article-title":"The effects of compression on the physiology of nerve roots","volume":"15","author":"Rydevik","year":"1992","journal-title":"J. Manipulative Physiol. Ther."},{"key":"mepae28edbib52","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1097\/00007632-198906000-00004","type":"journal-article","article-title":"Pressure increase in the dorsal root ganglion following mechanical compression. Closed compartment syndrome in nerve roots","volume":"14","author":"Rydevik","year":"1989","journal-title":"Spine"},{"key":"mepae28edbib53","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1097\/00007632-199105000-00001","type":"journal-article","article-title":"Effects of acute, graded compression on spinal nerve root function and structure. An experimental study of the pig cauda equina","volume":"16","author":"Rydevik","year":"1991","journal-title":"Spine"},{"key":"mepae28edbib54","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1097\/00007632-198401000-00004","type":"journal-article","article-title":"Pathoanatomy and pathophysiology of nerve root compression","volume":"9","author":"Rydevik","year":"1984","journal-title":"Spine"},{"key":"mepae28edbib55","first-page":"128","type":"book","article-title":"Biomechanics of peripheral nerves and spinal nerve roots","author":"Rydevik","year":"2012","edition":"4th edn"},{"key":"mepae28edbib56","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.51772","type":"other","article-title":"The axonal actin-spectrin lattice acts as a tension buffering shock absorber","author":"Sens","year":"2020"},{"key":"mepae28edbib57","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1089\/neu.2008.0621","type":"journal-article","article-title":"Structural and functional changes in nerve roots due to tension at various strains and strain rates: an in-vivo study","volume":"26","author":"Singh","year":"2009","journal-title":"J. Neurotrauma"},{"key":"mepae28edbib58","doi-asserted-by":"publisher","first-page":"1669","DOI":"10.1016\/J.JBIOMECH.2005.04.023","type":"journal-article","article-title":"Mechanical properties of spinal nerve roots subjected to tension at different strain rates","volume":"39","author":"Singh","year":"2006","journal-title":"J. Biomech."},{"key":"mepae28edbib59","first-page":"123","type":"journal-article","article-title":"Structure and composition of the outer connective tissue sheaths of peripheral nerve","volume":"186","author":"Stolinski","year":"1995","journal-title":"J. Anat."},{"key":"mepae28edbib60","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1177\/0018720811413389","type":"journal-article","article-title":"Physical and cognitive effects of virtual reality integrated training","volume":"53","author":"Stone","year":"2011","journal-title":"Hum. Factors"},{"key":"mepae28edbib61","doi-asserted-by":"publisher","first-page":"2089","DOI":"10.1097\/00007632-199609150-00006","type":"journal-article","article-title":"The effects of mechanical compression and hypoxia on nerve root and dorsal root ganglia. An analysis of ectopic firing using an in vitro model","volume":"21","author":"Sugawara","year":"1996","journal-title":"Spine"},{"key":"mepae28edbib62","doi-asserted-by":"publisher","first-page":"2003","DOI":"10.1097\/00007632-199910010-00007","type":"journal-article","article-title":"Nerve root pressure in lumbar disc herniation","volume":"24","author":"Takahashi","year":"1999","journal-title":"Spine"},{"key":"mepae28edbib63","doi-asserted-by":"publisher","DOI":"10.1016\/j.msksp.2022.102637","type":"journal-article","article-title":"Incidence of cervical kyphosis and cervical posterior translation in neck pain associated with radiological evidence of degenerative disc disease","volume":"62","author":"Takahashi","year":"2022","journal-title":"Musculoskelet Sci. Pract."},{"key":"mepae28edbib64","first-page":"63","type":"journal-article","article-title":"Strain rate effects on the tensile behavior of fiber bundles isolated from nerve root","volume":"2","author":"Tamura","year":"2015","journal-title":"J. Sustain. Res. Eng."},{"key":"mepae28edbib65","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1302\/0301-620X.74B1.1732240","type":"journal-article","article-title":"Experimental stretch neuropathy. Changes in nerve conduction under tension","volume":"74-B","author":"Wall","year":"1992","journal-title":"J. Bone Joint Surg. Br."},{"key":"mepae28edbib66","doi-asserted-by":"publisher","first-page":"1472","DOI":"10.1589\/jpts.29.1472","type":"journal-article","article-title":"Non-surgical relief of cervical radiculopathy through reduction of forward head posture and restoration of cervical lordosis: a case report","volume":"29","author":"Wickstrom","year":"2017","journal-title":"J. Phys. Ther. Sci."},{"key":"mepae28edbib67","doi-asserted-by":"publisher","first-page":"1811","DOI":"10.1007\/s00586-019-06024-y","type":"journal-article","article-title":"Ligamental compartments and their relation to the passing spinal nerves are detectable with MRI inside the lumbar neural foramina","volume":"28","author":"Wiersbicki","year":"2019","journal-title":"Eur. Spine J."},{"key":"mepae28edbib68","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1115\/1.1695571","type":"journal-article","article-title":"Mechanical thresholds for initiation and persistence of pain following nerve root injury: mechanical and chemical contributions at injury","volume":"126","author":"Winkelstein","year":"2004","journal-title":"J. Biomech. Eng."},{"key":"mepae28edbib69","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1097\/00007632-200201010-00009","type":"journal-article","article-title":"The role of mechanical deformation in lumbar radiculopathy","volume":"27","author":"Winkelstein","year":"2002","journal-title":"Spine"},{"key":"mepae28edbib70","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.920991","type":"journal-article","article-title":"Electrophysiological, biomechanical, and finite element analysis study of sacral nerve injury caused by sacral fracture","volume":"10","author":"Xu","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"key":"mepae28edbib71","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1097\/00007632-199502001-00001","type":"journal-article","article-title":"Chronic nerve root compression. Pathophysiologic mechanism of nerve root dysfunction","volume":"20","author":"Yoshizawa","year":"1995","journal-title":"Spine"}],"container-title":["Medical Engineering & Physics"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1873-4030\/ae28ed","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1873-4030\/ae28ed\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1873-4030\/ae28ed\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1873-4030\/ae28ed\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T21:28:37Z","timestamp":1768944517000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1873-4030\/ae28ed"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,20]]},"references-count":71,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,1,20]]},"published-print":{"date-parts":[[2026,2,2]]}},"URL":"https:\/\/doi.org\/10.1088\/1873-4030\/ae28ed","relation":{},"ISSN":["1350-4533","1873-4030"],"issn-type":[{"value":"1350-4533","type":"print"},{"value":"1873-4030","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,20]]},"assertion":[{"value":"Mechanical behavior of nerve roots and pain mechanisms: insights and opportunities for advancement","name":"article_title","label":"Article Title"},{"value":"Medical Engineering & Physics","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2026 Institute of Physics and Engineering in Medicine. All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2025-06-12","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2025-11-02","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2026-01-20","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}