{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:01:37Z","timestamp":1791806497623,"version":"4.3.4"},"reference-count":37,"publisher":"IOP Publishing","issue":"1","license":[{"start":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T00:00:00Z","timestamp":1702425600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/page\/copyright"},{"start":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T00:00:00Z","timestamp":1702425600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"name":"Universitas Indonesia PUTI research gran","award":["NKB-1139\/UN2.RST\/HKP.05.00\/2022"],"award-info":[{"award-number":["NKB-1139\/UN2.RST\/HKP.05.00\/2022"]}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Biomed. Phys. Eng. Express"],"published-print":{"date-parts":[[2024,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Morphological changes can affect distribution of dose in patients. Determination of the dose distribution changes for each fraction radiotherapy can be done by relative\n                    <jats:italic>in vivo<\/jats:italic>\n                    dosimetry (IVD). This study analysed the distribution of doses per fraction based on the fluence map recorded by the electronic portal imaging device (EPID) of the patient\u2019s transit dose. This research examined cases involving the cervix, breast, and nasopharynx. Transit dose analysis was performed by calculating the gamma index (GI) with composite and field-by-field methods. The gamma passing rate (GPR) value was assessed for its correlation with the subject\u2019s body weight. In the case of the nasopharynx, breast, and cervix, the GPR value decreased as the fraction increased. In the case of the nasopharynx, the correlation between the GPR and fraction radiotherapy showed no difference when using either composite or field-by-field methods. However, in cases involving the cervix and breast, there was a difference in the correlation values between the composite and field-by-field methods, where the subject had a significant correlation (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.05) when it was done using a field-by-field method. In addition, the nasopharynx had the highest number of subjects with significant correlation (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.05) between GPR and body weight, followed by the cervix and breast. In the nasopharynx, breast, and cervix, the reproducibility of the dose distribution decreased. This decreased reproducibility was associated with changes in body weight.\n                  <\/jats:p>","DOI":"10.1088\/2057-1976\/ad124a","type":"journal-article","created":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T17:21:06Z","timestamp":1701796866000},"page":"015013","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of dose distribution reproducibility based on a fluence map of in vivo transit dose using an electronic portal imaging device"],"prefix":"10.1088","volume":"10","author":[{"given":"Didin","family":"Tardi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aninda","family":"Fitriandini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annisa Rahma","family":"Fauziah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wahyu Edy","family":"Wibowo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Titin","family":"Siswantining","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0028-1442","authenticated-orcid":false,"given":"Supriyanto Ardjo","family":"Pawiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2023,12,13]]},"reference":[{"key":"bpexad124abib1","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1002\/acm2.12285","article-title":"A study on the effect of detector resolution on gamma index passing rate for VMAT and IMRT QA","volume":"19","author":"Woon","year":"2018","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"bpexad124abib2","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1120\/jacmp.v13i5.3856","article-title":"Angular dependence correction of MatriXX and its application to composite dose verification","volume":"13","author":"Shimohigashi","year":"2012","journal-title":"Journal of Applied Clinical Medical Physics"},{"key":"bpexad124abib3","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1002\/acm2.12712","article-title":"Evaluation of interfraction setup variations for postmastectomy radiation therapy using EPID-based in vivo dosimetry","volume":"20","author":"Kang","year":"2019","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"bpexad124abib4","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1002\/acm2.12747","article-title":"Early clinical experience with varian halcyon V2 linear accelerator: dual-isocenter IMRT planning and delivery with portal dosimetry for gynecological cancer treatments","volume":"20","author":"Kim","year":"2019","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"bpexad124abib5","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1002\/acm2.12881","article-title":"Comprehensive validation of halcyon 2.0 plans and the implementation of patient specific QA with multiple detector platforms","volume":"21","author":"Laugeman","year":"2020","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"bpexad124abib6","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1002\/mp.14001","article-title":"Technical note: dosimetric characterization of the dynamic beam flattening MLC sequence on a ring shaped, jawless linear accelerator with double stacked MLC","volume":"47","author":"Bollinger","year":"2020","journal-title":"Med. Phys."},{"key":"bpexad124abib7","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1120\/jacmp.v17i6.6336","article-title":"EPID-based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams","volume":"17","author":"Miri","year":"2016","journal-title":"Journal of Applied Clinical Medical Physics"},{"key":"bpexad124abib8","doi-asserted-by":"crossref","DOI":"10.1002\/acm2.13585","article-title":"Using eclipse scripting to fully automate in-vivo image analysis to improve treatment quality and safety","volume":"23","author":"Chalise","year":"2022","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"bpexad124abib9","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1002\/acm2.12568","article-title":"Characterization of the Halcyon(TM) multileaf collimator system","volume":"20","author":"Lim","year":"2019","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"bpexad124abib10","doi-asserted-by":"crossref","first-page":"12064","DOI":"10.1088\/1742-6596\/1305\/1\/012064","article-title":"Quantitative evaluation of transmission EPID daily imaging on a Halcyon Linac","volume":"1305","author":"Jin","year":"2019","journal-title":"J. Phys. Conf. Ser."},{"key":"bpexad124abib11","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1002\/acm2.12749","article-title":"Evaluating the sensitivity of halcyon\u2019s automatic transit image acquisition for treatment error detection: a phantom study using static IMRT","volume":"20","author":"Ray","year":"2019","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"bpexad124abib12","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.phro.2020.08.003","article-title":"In vivo dosimetry in external beam photon radiotherapy: requirements and future directions for research, development, and clinical practice","volume":"15","author":"Olaciregui-Ruiz","year":"2020","journal-title":"Phys. Imaging Radiat. Oncol."},{"key":"bpexad124abib13","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1002\/acm2.12441","article-title":"EPID-based in vivo dosimetry using dosimetry check: overview and clinical experience in a 5-yr study including breast, lung, prostate, and head and neck cancer patients","volume":"20","author":"Nailon","year":"2019","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"bpexad124abib14","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/j.radonc.2013.08.048","article-title":"A comparison of the gamma index analysis in various commercial IMRT\/VMAT QA systems","volume":"109","author":"Hussein","year":"2013","journal-title":"Radiother. Oncol."},{"key":"bpexad124abib15","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1002\/acm2.12391","article-title":"Independent validation of machine performance check for the Halcyon and TrueBeam linacs for daily quality assurance","volume":"19","author":"Li","year":"2018","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"bpexad124abib16","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1002\/acm2.12805","article-title":"Analyses of integrated EPID images for on-treatment quality assurance to account for interfractional variations in volumetric modulated arc therapy","volume":"21","author":"Matsushita","year":"2020","journal-title":"Journal of Applied Clinical Medical Physics"},{"key":"bpexad124abib17","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/j.radonc.2014.03.021","article-title":"In vivo portal dosimetry for head-and-neck VMAT and lung IMRT: linking gamma-analysis with differences in dose-volume histograms of the PTV","volume":"112","author":"Rozendaal","year":"2014","journal-title":"Radiother. Oncol."},{"key":"bpexad124abib18","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.rpor.2018.05.003","article-title":"EPID-based daily verification of reproducibility of patients\u2019 irradiation with IMRT plans","volume":"23","author":"Kruszyna-Mochalska","year":"2018","journal-title":"Rep. Pract. Oncol. Radiother."},{"key":"bpexad124abib19","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.rpor.2012.06.003","article-title":"Exit fluence analysis using portal dosimetry in volumetric modulated arc therapy","volume":"17","author":"Sukumar","year":"2012","journal-title":"Reports of Practical Oncology & Radiotherapy."},{"key":"bpexad124abib20","doi-asserted-by":"crossref","DOI":"10.1002\/mp.13045","article-title":"Establishing action threshold for change in patient anatomy using EPID gamma analysis and PTV coverage for head and neck radiotherapy treatment","author":"Piron","year":"2018","journal-title":"Med. Phys."},{"key":"bpexad124abib21","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/4149591","article-title":"Defining the optimal time of adaptive replanning in prostate cancer patients with weight change during volumetric arc radiotherapy: a dosimetric and mathematical analysis using the gamma index","volume":"2017","author":"Choi","year":"2017","journal-title":"Comput Math Methods Med."},{"key":"bpexad124abib22","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/0360-3016(91)90171-Y","article-title":"Tolerance of normal tissue to therapeutic irradiation","volume":"21","author":"Emami","year":"1991","journal-title":"International Journal of Radiation Oncology*Biology*Physics"},{"key":"bpexad124abib23","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/j.ijrobp.2019.06.2540","article-title":"International guideline on dose prioritization and acceptance criteria in radiation therapy planning for nasopharyngeal carcinoma","volume":"105","author":"Lee","year":"2019","journal-title":"International Journal of Radiation Oncology*Biology*Physics"},{"key":"bpexad124abib24","doi-asserted-by":"crossref","DOI":"10.1177\/1533033818779201","article-title":"A feasibility study for in vivo dosimetry procedure in routine clinical practice","volume":"17","author":"Falco","year":"2018","journal-title":"Technol. Cancer Res. Treat."},{"key":"bpexad124abib25","doi-asserted-by":"publisher","first-page":"5175","DOI":"10.1002\/cam4.4079","article-title":"A study to assess the dosimetric impact of the anatomical changes occurring in the parotid glands and tumour volume during intensity modulated radiotherapy using simultaneous integrated boost (IMRT-SIB) in head and neck squamous cell cancers","volume":"10","author":"Ghosh","year":"2021","journal-title":"Cancer Med."},{"key":"bpexad124abib26","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1002\/acm2.12677","article-title":"Dosimetric impact and detectability of multi-leaf collimator positioning errors on Varian Halcyon","volume":"20","author":"Gay","year":"2019","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"bpexad124abib27","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1002\/mp.12810","article-title":"Tolerance limits and methodologies for IMRT measurement-based verification QA: Recommendations of AAPM task group No. 218","volume":"45","author":"Miften","year":"2018","journal-title":"Med. Phys."},{"key":"bpexad124abib28","author":"Walpole","year":"2017"},{"key":"bpexad124abib29","doi-asserted-by":"publisher","DOI":"10.3390\/life12050722","article-title":"Criteria for verification and replanning based on the adaptive radiotherapy protocol \u2018best for adaptive radiotherapy\u2019 in head and neck cancer","volume":"12","author":"Bak","year":"2022","journal-title":"Life (Basel)"},{"key":"bpexad124abib30","doi-asserted-by":"publisher","first-page":"164","DOI":"10.4103\/0971-6203.139005","article-title":"Impact of repeat computerized tomography replans in the radiation therapy of head and neck cancers","volume":"39","author":"Bhandari","year":"2014","journal-title":"Journal of Medical Physics"},{"key":"bpexad124abib31","doi-asserted-by":"publisher","first-page":"281","DOI":"10.5603\/RPOR.a2021.0041","article-title":"Evaluation of two-dimensional electronic portal imaging device using integrated images during volumetric modulated arc therapy for prostate cancer","volume":"26","author":"Inui","year":"2021","journal-title":"Reports of Practical Oncology and Radiotherapy"},{"key":"bpexad124abib32","doi-asserted-by":"publisher","first-page":"27","DOI":"10.55981\/aij.2023.1203","article-title":"Dose evaluation of head and neck cancer IMRT treatment planning based on gamma index analysis of varian halcyon 2.0 linac","volume":"49","author":"Purwati","year":"2023","journal-title":"Atom Indonesia"},{"key":"bpexad124abib33","doi-asserted-by":"publisher","first-page":"533","DOI":"10.4103\/jcrt.JCRT_594_17","article-title":"Adaptive intensity-modulated radiotherapy in head-and-neck cancer: a volumetric and dosimetric study","volume":"15","author":"Burela","year":"2019","journal-title":"J. Cancer Res. Ther."},{"key":"bpexad124abib34","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1111\/ajco.12516","article-title":"Head and neck adaptive radiotherapy: Predicting the time to replan","volume":"12","author":"Brown","year":"2016","journal-title":"Asia Pac. J. Clin. Oncol."},{"key":"bpexad124abib35","doi-asserted-by":"publisher","first-page":"e375","DOI":"10.1016\/j.ijrobp.2011.07.004","article-title":"Monitoring dosimetric impact of weight loss with kilovoltage (KV) cone beam CT (CBCT) during parotid-sparing IMRT and concurrent chemotherapy","volume":"82","author":"Ho","year":"2012","journal-title":"International Journal of Radiation Oncology, Biology, Physics"},{"key":"bpexad124abib36","article-title":"Replanning criteria and timing definition for parotid protection-based adaptive radiation therapy in nasopharyngeal carcinoma","volume":"2015","author":"Yao","year":"2015","journal-title":"Bio. Med. Res. Int."},{"key":"bpexad124abib37","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.579917","article-title":"Radiotherapy for head and neck cancer: evaluation of triggered adaptive replanning in routine practice","volume":"10","author":"Figen","year":"2020","journal-title":"Front Oncol."}],"container-title":["Biomedical Physics &amp; Engineering Express"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/2057-1976\/ad124a","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/2057-1976\/ad124a\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/2057-1976\/ad124a","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/2057-1976\/ad124a\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/2057-1976\/ad124a\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/2057-1976\/ad124a\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/2057-1976\/ad124a\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/2057-1976\/ad124a\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T11:22:01Z","timestamp":1749900121000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/2057-1976\/ad124a"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,13]]},"references-count":37,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12,13]]},"published-print":{"date-parts":[[2024,1,1]]}},"URL":"https:\/\/doi.org\/10.1088\/2057-1976\/ad124a","relation":{"has-review":[{"id-type":"doi","id":"10.1088\/2057-1976\/AD124A\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1088\/2057-1976\/AD124A\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1088\/2057-1976\/AD124A\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1088\/2057-1976\/AD124A\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1088\/2057-1976\/AD124A\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1088\/2057-1976\/AD124A\/v2\/review1","asserted-by":"object"}]},"ISSN":["2057-1976"],"issn-type":[{"value":"2057-1976","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,13]]},"assertion":[{"value":"Analysis of dose distribution reproducibility based on a fluence map of in vivo transit dose using an electronic portal imaging device","name":"article_title","label":"Article Title"},{"value":"Biomedical Physics & Engineering Express","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2023 IOP Publishing Ltd. All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2023-09-06","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2023-12-05","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2023-12-13","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}