{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T18:36:16Z","timestamp":1789583776837,"version":"build-2803163510"},"reference-count":33,"publisher":"IOP Publishing","issue":"3","license":[{"start":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T00:00:00Z","timestamp":1710288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T00:00:00Z","timestamp":1710288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Biomed. Phys. Eng. Express"],"published-print":{"date-parts":[[2024,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The femur is one of the most important bone in the human body, as it supports the body\u2019s weight and helps with movement. The aging global population presents a significant challenge, leading to an increasing demand for artificial joints, particularly in knee and hip replacements, which are among the most prevalent surgical procedures worldwide. This study focuses on hip fractures, a common consequence of osteoporotic fractures in the elderly population. To accurately predict individual bone properties and assess fracture risk, patient-specific finite element models (FEM) were developed using CT data from healthy male individuals. The study employed ANSYS 2023 R2 software to estimate fracture loads under simulated single stance loading conditions, considering strain-based failure criteria. The FEM bone models underwent meticulous reconstruction, incorporating geometrical and mechanical properties crucial for fracture risk assessment. Results revealed an underestimation of the ultimate bearing capacity of bones, indicating potential fractures even during routine activities. The study explored variations in bone density, failure loads, and density\/load ratios among different specimens, emphasizing the complexity of bone strength determination. Discussion of findings highlighted discrepancies between simulation results and previous studies, suggesting the need for optimization in modelling approaches. The strain-based yield criterion proved accurate in predicting fracture initiation but required adjustments for better load predictions. The study underscores the importance of refining density-elasticity relationships, investigating boundary conditions, and optimizing models through <jats:italic>in vitro<\/jats:italic> testing for enhanced clinical applicability in assessing hip fracture risk. In conclusion, this research contributes valuable insights into developing patient-specific FEM bone models for clinical hip fracture risk assessment, emphasizing the need for further refinement and optimization for accurate predictions and enhanced clinical utility.<\/jats:p>","DOI":"10.1088\/2057-1976\/ad2ff3","type":"journal-article","created":{"date-parts":[[2024,3,4]],"date-time":"2024-03-04T22:25:15Z","timestamp":1709591115000},"page":"035006","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Patient-specific finite element analysis for assessing hip fracture risk in aging populations"],"prefix":"10.1088","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9399-685X","authenticated-orcid":false,"given":"Chethan","family":"K N","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Schmidt Genannt Waldschmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5677-9653","authenticated-orcid":false,"given":"John Valerian","family":"Corda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2374-3854","authenticated-orcid":false,"given":"Satish","family":"Shenoy B","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6384-1489","authenticated-orcid":false,"given":"Sawan","family":"Shetty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7010-7186","authenticated-orcid":false,"given":"Laxmikant G","family":"Keni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9545-4838","authenticated-orcid":false,"given":"Shyamasunder","family":"Bhat N","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5241-7720","authenticated-orcid":false,"given":"Nishant","family":"Nikam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5077-8927","authenticated-orcid":false,"given":"Senay","family":"Mihcin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2024,3,13]]},"reference":[{"key":"bpexad2ff3bib1","doi-asserted-by":"publisher","author":"OECD","year":"2021","DOI":"10.1787\/ae3016b9-en"},{"key":"bpexad2ff3bib2","doi-asserted-by":"publisher","first-page":"589","DOI":"10.13140\/RG.2.2.13686.80969","article-title":"A Review on Total Hip Replacement","volume":"2","author":"Sivasankar","year":"2016","journal-title":"International Research Journal in Advanced Engineering and Technology"},{"key":"bpexad2ff3bib3","doi-asserted-by":"publisher","first-page":"2461","DOI":"10.1007\/s00198-013-2323-8","article-title":"Bone mineral loss at the proximal femur in acute spinal cord injury","volume":"24","author":"Edwards","year":"2013","journal-title":"Osteoporosis International"},{"key":"bpexad2ff3bib4","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1016\/j.bone.2003.12.012","article-title":"The degree of mineralization is a determinant of bone strength: a study on human calcanei","volume":"34","author":"Follet","year":"2004","journal-title":"Bone"},{"key":"bpexad2ff3bib5","doi-asserted-by":"publisher","first-page":"2982","DOI":"10.1016\/j.jbiomech.2007.02.010","article-title":"Subject-specific finite element models can accurately predict strain levels in long bones","volume":"40","author":"Schileo","year":"2007","journal-title":"J. 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