{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T15:57:34Z","timestamp":1793894254618,"version":"4.8.0"},"reference-count":43,"publisher":"IOP Publishing","issue":"3","license":[{"start":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T00:00:00Z","timestamp":1713398400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/page\/copyright"},{"start":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T00:00:00Z","timestamp":1713398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100009693","name":"Little Giraffe Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100009693","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Cincinnati Children's Research Foundation","id":[{"id":"https:\/\/ror.org\/01hcyya48","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Parker B. Francis Foundation"},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["K99 HL 144822"],"award-info":[{"award-number":["K99 HL 144822"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Biomed. Phys. Eng. Express"],"published-print":{"date-parts":[[2024,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    . Thoracoabdominal MRI is limited by respiratory motion, especially in populations who cannot perform breath-holds. One approach for reducing motion blurring in radially-acquired MRI is respiratory gating. Straightforward \u2018hard-gating\u2019 uses only data from a specified respiratory window and suffers from reduced SNR. Proposed \u2018soft-gating\u2019 reconstructions may improve scan efficiency but reduce motion correction by incorporating data with nonzero weight acquired outside the specified window. However, previous studies report conflicting benefits, and importantly the choice of soft-gated weighting algorithm and effect on image quality has not previously been explored. The purpose of this study is to map how variable soft-gated weighting functions and parameters affect signal and motion blurring in respiratory-gated reconstructions of radial lung MRI, using neonates as a model population.\n                    <jats:italic>Methods<\/jats:italic>\n                    . Ten neonatal inpatients with respiratory abnormalities were imaged using a 1.5 T neonatal-sized scanner and 3D radial ultrashort echo-time (UTE) sequence. Images were reconstructed using ungated, hard-gated, and several soft-gating weighting algorithms (exponential, sigmoid, inverse, and linear weighting decay outside the period of interest), with %N\n                    <jats:sub>proj<\/jats:sub>\n                    representing the relative amount of data included. The apparent SNR (aSNR) and motion blurring (measured by the maximum derivative of image intensity at the diaphragm, MDD) were compared between reconstructions.\n                    <jats:italic>Results<\/jats:italic>\n                    . Soft-gating functions produced higher aSNR and lower MDD than hard-gated images using equivalent %N\n                    <jats:sub>proj<\/jats:sub>\n                    , as expected. aSNR was not identical between different gating schemes for given %N\n                    <jats:sub>proj<\/jats:sub>\n                    . While aSNR was approximately linear with %N\n                    <jats:sub>proj<\/jats:sub>\n                    for each algorithm, MDD performance diverged between functions as %N\n                    <jats:sub>proj<\/jats:sub>\n                    decreased. Algorithm performance was relatively consistent between subjects, except in images with high noise.\n                    <jats:italic>Conclusion<\/jats:italic>\n                    . The algorithm selection for soft-gating has a notable effect on image quality of respiratory-gated MRI; the timing of included data across the respiratory phase, and not simply the amount of data, plays an important role in aSNR. The specific soft-gating function and parameters should be considered for a given imaging application\u2019s requirements of signal and sharpness.\n                  <\/jats:p>","DOI":"10.1088\/2057-1976\/ad3cdd","type":"journal-article","created":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T18:20:41Z","timestamp":1712773241000},"page":"035030","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of weighting algorithms to mitigate respiratory motion in free-breathing neonatal pulmonary radial UTE-MRI"],"prefix":"10.1088","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9479-5427","authenticated-orcid":true,"given":"Deep B","family":"Gandhi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6233-161X","authenticated-orcid":true,"given":"Nara S","family":"Higano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D","family":"Hahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2713-6533","authenticated-orcid":true,"given":"Chamindu C","family":"Gunatilaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis A","family":"Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean B","family":"Fain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason C","family":"Woods","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alister J","family":"Bates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2024,4,18]]},"reference":[{"key":"bpexad3cddbib1","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.2214\/ajr.143.6.1175","article-title":"Magnetic resonance imaging with respiratory gating: techniques and advantages","volume":"143","author":"Ehman","year":"1984","journal-title":"AJR Am. 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