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The proposed model employs neural architecture search network - mobile(NASNet-Mobile) model for ASD detection, which is integrated with an explainable artificial intelligence (XAI) technique called local interpretable model-agnostic explanations (LIME) for increased transparency of ASD classification. The model is trained on sMRI images of two age groups taken from autism brain imaging data exchange-I (ABIDE-I) dataset. The proposed model yielded accuracy of 0.9607, F1-score of 0.9614, specificity of 0.9774, sensitivity of 0.9451, negative predicted value (NPV) of 0.9429, positive predicted value (PPV) of 0.9783 and the diagnostic odds ratio of 745.59 for 2 to 11 years age group compared to 12 to 18 years group. These results are superior compared to other state of the art models Inception v3 and SqueezeNet.<\/jats:p>","DOI":"10.1088\/2057-1976\/addbe7","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T22:47:41Z","timestamp":1747954061000},"page":"045006","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["An interpretable deep learning approach for autism spectrum disorder detection in children using NASNet-mobile"],"prefix":"10.1088","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7234-2363","authenticated-orcid":true,"given":"Venkata Ratna Prabha","family":"K","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinni Hima","family":"Bindu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K Rama","family":"Devi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2025,6,3]]},"reference":[{"key":"bpexaddbe7bib1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2024.110315","article-title":"Early detection of autism spectrum disorder using explainable ai and optimized teaching strategies","volume":"413","author":"Alzakari","year":"2025","journal-title":"J. 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