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Express"],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cardiovascular diseases are among the leading causes of global mortality, second only to cancer. Following a myocardial infarction, cardiac tissue undergoes irreversible damage. Due to the limited regenerative capacity of adult cardiomyocytes (CMs), there is a pressing need for supportive biomaterials that can mimic the heart\u2019s biochemical and biomechanical microenvironment while promoting cellular proliferation and tissue regeneration. Electrospun nanofiber scaffolds have emerged as a promising approach due to their ability to replicate the fibrous, anisotropic architecture of native cardiac tissue. These scaffolds are widely employed in cardiac tissue engineering, particularly for the development of cardiac patches. Incorporating electroconductive materials into nanofibrous scaffolds has been explored as a strategy to enhance intracellular signaling and promote synchronized CM contractions via electroactive substrates. Unlike commercialized cardiac patches, which primarily offer mechanical support without enabling tissue regeneration, emerging electroconductive scaffolds offer significant potential to overcome this limitation. This review evaluates various nanofiber-based cardiac patches with electrical conductivity, focusing on key components such as carbon-based materials, metallic nanoparticles, conductive polymers, and piezoelectric materials. Additionally, we discuss the role of electroconductive nanomaterials in improving the electrical and mechanical properties of cardiac scaffolds. The article also provides an overview of recent advancements in electroconductive electrospun scaffolds for cardiac tissue engineering and outlines current challenges and future prospects in this field.<\/jats:p>","DOI":"10.1088\/2057-1976\/ae7803","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T09:15:18Z","timestamp":1780650918000},"page":"042002","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Advanced electroactive nanofibrous patches for cardiac tissue regeneration: a comprehensive review"],"prefix":"10.1088","volume":"12","author":[{"given":"Bahareh","family":"Doustvandi","sequence":"first","affiliation":[{"name":"Amirkabir University of Technology (Tehran Polytechnic)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8864-3876","authenticated-orcid":true,"given":"Fatemeh","family":"Edrisi","sequence":"additional","affiliation":[{"name":"Tarbiat Modares University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1832-0163","authenticated-orcid":true,"given":"Rana","family":"Imani","sequence":"additional","affiliation":[{"name":"Amirkabir University of Technology (Tehran Polytechnic)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9157-1826","authenticated-orcid":true,"given":"Maryam","family":"Yousefzadeh","sequence":"additional","affiliation":[{"name":"Amirkabir University of Technology (Tehran Polytechnic)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2026,7,10]]},"reference":[{"key":"bpexae7803bib1","doi-asserted-by":"publisher","first-page":"e41","DOI":"10.1161\/CIR.0000000000001303","type":"journal-article","article-title":"2025 Heart disease and stroke statistics: a report of US and global data from the American Heart Association","volume":"151","author":"Martin","year":"2025","journal-title":"Circulation"},{"key":"bpexae7803bib2","doi-asserted-by":"publisher","first-page":"e146","DOI":"10.1161\/CIR.0000000000000485","type":"journal-article","article-title":"Heart disease and stroke statistics\u20142017 update: a report from the American Heart Association","volume":"135","author":"Benjamin","year":"2017","journal-title":"Circulation"},{"key":"bpexae7803bib3","doi-asserted-by":"publisher","first-page":"3677","DOI":"10.1002\/smll.201600178","type":"journal-article","article-title":"Reduced graphene oxide\u2010gelMA hybrid hydrogels as scaffolds for cardiac tissue engineering","volume":"12","author":"Shin","year":"2016","journal-title":"Small"},{"key":"bpexae7803bib4","doi-asserted-by":"publisher","first-page":"159-175","DOI":"10.1021\/bk-2014-1175.ch010","type":"book","article-title":"Novel Cardiac Patch Development Using Natural Biopolymers","volume":"1175","author":"Dubey","year":"2014"},{"key":"bpexae7803bib5","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.mehy.2018.10.005","type":"journal-article","article-title":"\u03b2-PVDF based electrospun nanofibers\u2013A promising material for developing cardiac patches","volume":"122","author":"Arumugam","year":"2019","journal-title":"Med. 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