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This review provides a clear overview of how key cellular components such as mesenchymal stem cells, adipose-derived stem cells (ADSCs), fibroblasts, and multicellular systems contribute to important wound healing processes like immunomodulation, angiogenesis, cell proliferation, and re-epithelialisation. It also explores how bioprinting factors, including bioink rheology, cross-linking methods, and processing conditions, influence printability, the structural stability of scaffolds, and cell survival. The close relationship between scaffold design and how cells respond is emphasised as a key factor in determining how effective the treatment will be. Although pre-clinical studies have shown promising results, bringing this research into real-world clinical use remains challenging due to issues like lack of standardisation, difficulties in scaling up, regulatory hurdles, and high costs.<\/jats:p>","DOI":"10.1088\/2057-1976\/aea426","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T22:48:13Z","timestamp":1788907693000},"page":"052002","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Cell-laden 3D bioprinted hydrogels for wound healing: cellular mechanism, bioprinting determinants and translational perspectives"],"prefix":"10.1088","volume":"12","author":[{"given":"Navjeet","family":"Singh","sequence":"first","affiliation":[{"name":"Punjabi University"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7220-5660","authenticated-orcid":true,"given":"Dimple Sethi","family":"Chopra","sequence":"additional","affiliation":[{"name":"Punjabi University"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Ankush","family":"Kumar","sequence":"additional","affiliation":[{"name":"Punjabi University"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"validation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Abhishek","family":"Gupta","sequence":"additional","affiliation":[{"name":"University of Wolverhampton, City Campus, Wulfruna St."}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Dhandeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Punjabi University"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"resources","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Nirmal","family":"Singh","sequence":"additional","affiliation":[{"name":"Punjabi University"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"resources","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]}],"member":"266","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"bpexaea426bib1","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s12325-017-0478-y","type":"journal-article","article-title":"Chronic wound healing: a review of current management and treatments","volume":"34","author":"Han","year":"2017","journal-title":"Adv. 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