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Express"],"published-print":{"date-parts":[[2026,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Objective.<\/jats:italic>\n                    This study aimed to evaluate the feasibility of background quality control (QC) as a novel approach for monitoring time-of-flight (TOF) and energy drift in uMI 550 positron emission tomography\u2013computed tomography (PET\/CT) systems.\n                    <jats:italic>Methods.<\/jats:italic>\n                    Three experiments were conducted to compare\n                    <jats:sup>176<\/jats:sup>\n                    Lu background QC with conventional radioactive source QC. These included multi-system validation, long-term clinical tracking, and anomaly detection. System performance was assessed by calculating TOF drift, energy drift, TOF deviation, and energy deviation. The Wilcoxon signed-rank test compared energy and TOF drift between\n                    <jats:sup>176<\/jats:sup>\n                    Lu background QC and\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG rod phantom QC, while the Friedman rank sum test compared parameters among\n                    <jats:sup>176<\/jats:sup>\n                    Lu background QC,\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG rod phantom, and\n                    <jats:sup>68<\/jats:sup>\n                    Ge cylinder phantom QC.\n                    <jats:italic>Results.<\/jats:italic>\n                    Long-term tracking and anomaly detects showed, TOF deviation remained below 7.6 ps and energy deviation below 1%. Over the five-month period, TOF drift remained stable, whereas energy drift showed a slight decrease under both\n                    <jats:sup>176<\/jats:sup>\n                    Lu background and radioactive source QC.\n                    <jats:sup>176<\/jats:sup>\n                    Lu Background,\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG rod phantom, and\n                    <jats:sup>68<\/jats:sup>\n                    Ge cylinder phantom QC methods all reliably detected variations in system energy and TOF drift.\n                    <jats:italic>Conclusions.<\/jats:italic>\n                    <jats:sup>176<\/jats:sup>\n                    Lu Background QC offers a feasible and reliable alternative to\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG rod phantom QC for daily PET\/CT QC. It reduces radiation exposure and simplifies operation, while periodic cross-validation with\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG rod phantom QC every six to twelve months remains advisable to ensure long-term system stability.\n                  <\/jats:p>","DOI":"10.1088\/2057-1976\/aeac31","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T22:48:00Z","timestamp":1790290080000},"page":"055058","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Operational reliability of an automated\n                    <sup>176<\/sup>\n                    Lu-based daily quality control system: a five-month continuous monitoring study in digital PET\/CT"],"prefix":"10.1088","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5350-0523","authenticated-orcid":true,"given":"Shuguang","family":"Chen","sequence":"first","affiliation":[{"name":"Zhongshan Hospital"},{"name":"Fudan University"},{"name":"Shanghai Institute of Medical Imaging"},{"name":"This author has contributed equally"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"}]},{"given":"Xiaoguang","family":"Hou","sequence":"additional","affiliation":[{"name":"Zhongshan Hospital"},{"name":"Fudan University"},{"name":"Shanghai Institute of Medical Imaging"},{"name":"This author has contributed equally"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"software","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"}]},{"given":"Chao","family":"Wang","sequence":"additional","affiliation":[{"name":"United Imaging Healthcare"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"software","vocabulary":"credit"}]},{"given":"Hongcheng","family":"Shi","sequence":"additional","affiliation":[{"name":"Zhongshan Hospital"},{"name":"Fudan University"},{"name":"Shanghai Institute of Medical Imaging"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]}],"member":"266","published-online":{"date-parts":[[2026,10,21]]},"reference":[{"key":"bpexaeac31bib1","doi-asserted-by":"publisher","first-page":"224","DOI":"10.2174\/1874471010902040224","type":"journal-article","article-title":"Clinical applications of positron emission tomography (PET) imaging in medicine: oncology, brain diseases and cardiology","volume":"2","author":"Kitson","year":"2009","journal-title":"Curr. 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All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2025-11-18","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2026-09-24","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2026-10-21","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}