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The study was carried out by partitioning each quantum processing unit (QPU) into several sub-units with the same topology to implement individual QSVM instances. We conducted parallelization experiments with three IBM backends with more than 100 qubits, ranking the sub-units based on their susceptibility to noise. Data-driven simulations show how, under certain restrictions, parallelized genetic optimization can occur with the tested devices when retaining the top 20% ranked sub-units in the QPU.<\/jats:p>","DOI":"10.1088\/2632-2153\/adb4bc","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T22:53:40Z","timestamp":1739314420000},"page":"015056","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":13,"title":["Enhanced feature encoding and classification on distributed quantum hardware"],"prefix":"10.1088","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5201-5920","authenticated-orcid":true,"given":"R","family":"Moretti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0493-695X","authenticated-orcid":false,"given":"A","family":"Giachero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2502-6739","authenticated-orcid":false,"given":"V","family":"Radescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1718-1314","authenticated-orcid":true,"given":"M","family":"Grossi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2025,2,28]]},"reference":[{"key":"mlstadb4bcbib1","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1038\/s41586-023-06096-3","article-title":"Evidence for the utility of quantum computing before fault tolerance","volume":"618","author":"Kim","year":"2023","journal-title":"Nature"},{"key":"mlstadb4bcbib2","doi-asserted-by":"crossref","DOI":"10.1109\/QSW59989.2023.00028","article-title":"Quantum utility\u2014definition and assessment of a practical quantum advantage","author":"Herrmann","year":"2023"},{"key":"mlstadb4bcbib3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.physrep.2022.08.003","article-title":"The variational quantum eigensolver: a review of methods and best practices","volume":"986","author":"Tilly","year":"2022","journal-title":"Phys. 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