{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T13:31:48Z","timestamp":1740144708753,"version":"3.37.3"},"reference-count":55,"publisher":"IOP Publishing","issue":"05","license":[{"start":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T00:00:00Z","timestamp":1715040000000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/iopscience.iop.org\/page\/copyright"},{"start":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T00:00:00Z","timestamp":1715040000000},"content-version":"tdm","delay-in-days":6,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["J. Inst."],"published-print":{"date-parts":[[2024,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>In this work a detector prototype built as an array of\n  Scintillating Plastic Optical fibers (SPOFs) is presented. The\n  primary aim of this detector is to improve spatial resolution,\n  provide real-time dose mapping and a tissue equivalent detector in\n  radiobiology experiments. Details on the design and construction are\n  provided along with the initial tests carried out using low-energy\n  X-ray and electrons from a <jats:sup>90<\/jats:sup>Sr source. Regarding the design\n  and construction of the detector, the mechanical design of the\n  irradiation box is presented and the Quality Assurance (QA) the\n  optical fiber arrays were subjected to is discussed. The QA\n  measurements show that the alignment of the optical fibers is within\n  acceptable tolerances for dose readout. After the detector assembly,\n  correction factors for each fiber were extracted from tests using a\n  collimated X-ray beam. Special care was taken to ensure that each\n  fiber is submitted to the same dose. Broad field tests show that the\n  measurements are reproducible to within 3 %. Potential innovative\n  features of this system for radiobiological experiments are\n  discussed as well as the future follow-up of the prototype.<\/jats:p>","DOI":"10.1088\/1748-0221\/19\/05\/p05006","type":"journal-article","created":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T17:33:23Z","timestamp":1715103203000},"page":"P05006","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Development of a plastic scintillating optical fibers array dosimeter for radiobiology"],"prefix":"10.1088","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9453-6871","authenticated-orcid":false,"given":"D.R.","family":"Guerreiro","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7006-0864","authenticated-orcid":false,"given":"J.G.","family":"Saraiva","sequence":"additional","affiliation":[]},{"given":"M.J.","family":"Borges","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4359-493X","authenticated-orcid":false,"given":"J.M.","family":"Sampaio","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3834-1762","authenticated-orcid":false,"given":"L.","family":"Peralta","sequence":"additional","affiliation":[]}],"member":"266","published-online":{"date-parts":[[2024,5,7]]},"reference":[{"year":"2018","key":"b2a763aa9d9c41c780fc1ca564f79f52f"},{"key":"b05f83d65aa38423b4dcd20ac8cd73ba4","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1259\/bjr\/31372149","article-title":"21 years of Biologically Effective Dose","volume":"83","author":"Fowler","year":"2010","journal-title":"The British Journal of Radiology"},{"key":"bb4fd54d5755c3a246b169c0aacc3ff3c","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1134\/S1063779619010027","article-title":"Radiation Hardness of Scintillation Detectors Based on Organic Plastic Scintillators and Optical Fibers","volume":"50","author":"Kharzheev","year":"2019","journal-title":"Phys. Part. Nucl."},{"key":"bb4fef878a29e37c6adca7dcf4205d831","doi-asserted-by":"publisher","first-page":"1711","DOI":"10.1118\/1.3116362","article-title":"Characterization of a water-equivalent fiber-optic coupled dosimeter for use in diagnostic radiology","volume":"36","author":"Hyer","year":"2009","journal-title":"Medical Physics"},{"key":"bd6c31c8d022d4a50c1d085fb2fbc997a","doi-asserted-by":"publisher","first-page":"3177","DOI":"10.1118\/1.3590367","article-title":"Organ dose and inherent uncertainty in helical CT dosimetry due to quasiperiodic dose distributions: Organ dose and uncertainty in helical CT dosimetry","volume":"38","author":"Winslow","year":"2011","journal-title":"Medical Physics"},{"key":"b5ea956d10b9a6af191c96631c24a630c","doi-asserted-by":"publisher","first-page":"5308","DOI":"10.1118\/1.4738964","article-title":"Validating plastic scintillation detectors for photon dosimetry in the radiologic energy range","volume":"39","author":"Lessard","year":"2012","journal-title":"Medical Physics"},{"key":"b5f93454a7b4c946f4ed70c204f5ae33c","doi-asserted-by":"publisher","first-page":"6305","DOI":"10.3390\/s140406305","article-title":"Measurement of Entrance Surface Dose on an Anthropomorphic Thorax Phantom Using a Miniature Fiber-Optic Dosimeter","volume":"14","author":"Yoo","year":"2014","journal-title":"Sensors"},{"key":"b7e96aabd51a7b81a519329ee8e84dc85","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1118\/1.4906206","article-title":"Characterizing energy dependence and count rate performance of a dual scintillator fiber-optic detector for computed tomography","volume":"42","author":"Hoerner","year":"2015","journal-title":"Medical Physics"},{"key":"bfe25868061e49523122fb678c11a089e","first-page":"680","article-title":"A novel tool for in vivo dosimetry in diagnostic and interventional radiology using plastic scintillation detectors","author":"Boivin","year":"2015"},{"key":"b3bbe3b66ed025ab8274fb17994d6eec7","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/j.nima.2017.10.021","article-title":"Plastic scintillation detectors for dose monitoring in digital breast tomosynthesis","volume":"877","author":"Antunes","year":"2018","journal-title":"Nucl. Instrum. Meth. A"},{"key":"bc6770f057371aeebe099bb9bee902b10","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.radmeas.2018.09.012","article-title":"Evaluation of an optical scintillating fiber detector for CT dosimetry","volume":"119","author":"Gillet","year":"2018","journal-title":"Radiation Measurements"},{"key":"b1ebfd190f82c1c7f848aca3ce47ac738","doi-asserted-by":"publisher","first-page":"90","DOI":"10.3390\/s22010090","article-title":"Characterization of an Innovative Detector Based on Scintillating Fiber for Personalized Computed Tomography Dosimetry","volume":"22","author":"Devic","year":"2021","journal-title":"Sensors"},{"key":"bf2e589b1826c64d36ec69636ceb4b06f","doi-asserted-by":"publisher","DOI":"10.1118\/1.4803510","article-title":"On the use of a single-fiber multipoint plastic scintillation detector for 192Ir high-dose-rate brachytherapy","volume":"40","author":"Therriault-Proulx","year":"2013","journal-title":"Medical Physics"},{"key":"b42b9c6a34e77861efbcd95ddb35ccce9","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1016\/j.nima.2015.01.072","article-title":"Brachytherapy dosimeter with silicon photomultipliers","volume":"787","author":"Moutinho","year":"2015","journal-title":"Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment"},{"key":"b09da8e1636de517ceada4d883aacbbfc","doi-asserted-by":"publisher","first-page":"2412","DOI":"10.1002\/mp.13498","article-title":"Optimization of a multipoint plastic scintillator dosimeter for high dose rate brachytherapy","volume":"46","author":"Linares Rosales","year":"2019","journal-title":"Medical Physics"},{"key":"b8c333d3d02f25d822f8f8b629089c072","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1118\/1.4903757","article-title":"Characterization of the Exradin W1 scintillator for use in radiotherapy","volume":"42","author":"Carrasco","year":"2015","journal-title":"Medical Physics"},{"key":"b7168fb0e4b36259ee7787b09cc1393b3","doi-asserted-by":"publisher","first-page":"R305","DOI":"10.1088\/0031-9155\/61\/20\/r305","article-title":"Review of plastic and liquid scintillation dosimetry for photon, electron, and proton therapy","volume":"61","author":"Beaulieu","year":"2016","journal-title":"Physics in Medicine and Biology"},{"key":"bed35b79486605679c61b2cd9376145df","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1002\/acm2.12705","article-title":"Use of a plastic scintillator detector for patient-specific quality assurance of VMAT SRS","volume":"20","author":"Snyder","year":"2019","journal-title":"Journal of Applied Clinical Medical Physics"},{"key":"b475ab6fb4e38bd680ceccde1bc505062","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1093\/rpd\/ncz230","article-title":"THE USE OF THE EXRADIN W1 PLASTIC SCINTILLATOR FOR MEASUREMENTS IN EXTERNAL RADIOTHERAPY","volume":"186","author":"Koniarov\u00e1","year":"2019","journal-title":"Radiation Protection Dosimetry"},{"key":"bd317c6b0908dcc223ceecc6280189399","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/s0168-9002(96)00754-1","article-title":"Scintillating optical fibers in mammography","volume":"382","author":"Gennaro","year":"1996","journal-title":"Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment"},{"key":"bb017d7da0ab27fbb0950d0361f06c19f","doi-asserted-by":"publisher","first-page":"4621","DOI":"10.1088\/0031-9155\/59\/16\/4621","article-title":"Response of plastic scintillators to low-energy photons","volume":"59","author":"Peralta","year":"2014","journal-title":"Physics in Medicine and Biology"},{"key":"bae28ceca1903e90169ad01f60691c27e","doi-asserted-by":"publisher","first-page":"5569","DOI":"10.1088\/0031-9155\/61\/15\/5569","article-title":"A systematic characterization of the low-energy photon response of plastic scintillation detectors","volume":"61","author":"Boivin","year":"2016","journal-title":"Physics in Medicine and Biology"},{"key":"b27a637dea458a13ffc3e2638035dcaf8","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1088\/0031-9155\/58\/2\/261","article-title":"Quenching correction for volumetric scintillation dosimetry of proton beams","volume":"58","author":"Robertson","year":"2012","journal-title":"Physics in Medicine and Biology"},{"key":"b93a3f1c808549d97f5bde576d7185ce3","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1002\/acm2.12143","article-title":"Quality assurance in proton beam therapy using a plastic scintillator and a commercially available digital camera","volume":"18","author":"Almurayshid","year":"2017","journal-title":"Journal of Applied Clinical Medical Physics"},{"key":"bdd3d3dc7596d55579a14ad0f62f997b9","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6560\/ab12f2","article-title":"Ionization quenching in scintillators used for dosimetry of mixed particle fields","volume":"64","author":"Christensen","year":"2019","journal-title":"Physics in Medicine amp; Biology"},{"key":"bdb9546c3d85622cbf70abea27cf305a7","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1088\/0370-1298\/64\/10\/303","article-title":"Scintillations from Organic Crystals: Specific Fluorescence and Relative Response to Different Radiations","volume":"64","author":"Birks","year":"1951","journal-title":"Proc. Phys. Soc. A"},{"key":"bf799ac2e68f72226b560ddbe5511a99f","doi-asserted-by":"publisher","first-page":"7767","DOI":"10.1088\/0031-9155\/57\/23\/7767","article-title":"Determination of the quenching correction factors for plastic scintillation detectors in therapeutic high-energy proton beams","volume":"57","author":"Wang","year":"2012","journal-title":"Physics in Medicine and Biology"},{"key":"b6c7ca5c00ea076c11f6d785c65d61cd0","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6560\/aabd2d","article-title":"Characterization of the exradin W1 plastic scintillation detector for small field applications in proton therapy","volume":"63","author":"Hoehr","year":"2018","journal-title":"Physics in Medicine amp; Biology"},{"key":"b82b8ba2122beceef228eb1f669ad341b","doi-asserted-by":"publisher","DOI":"10.1088\/1748-0221\/16\/02\/P02035","article-title":"Measurement of Proton Quenching in a Plastic Scintillator Detector","volume":"16","author":"Awe","year":"2021","journal-title":"JINST"},{"key":"bd2f9c6c667bf14d2517df01e862c8996","doi-asserted-by":"publisher","first-page":"6763","DOI":"10.1118\/1.3664007","article-title":"A new water-equivalent 2D plastic scintillation detectors array for the dosimetry of megavoltage energy photon beams in radiation therapy","volume":"38","author":"Guillot","year":"2011","journal-title":"Medical Physics"},{"key":"b779e9fb83f2a18829cbb8b3a81c43e61","doi-asserted-by":"publisher","first-page":"2140","DOI":"10.1118\/1.3562896","article-title":"Spectral method for the correction of the Cerenkov light effect in plastic scintillation detectors: A comparison study of calibration procedures and validation in Cerenkov light-dominated situations","volume":"38","author":"Guillot","year":"2011","journal-title":"Medical Physics"},{"key":"bc9385f366385271b592e4ce4a26d461a","doi-asserted-by":"publisher","first-page":"P11015","DOI":"10.1088\/1748-0221\/12\/11\/p11015","article-title":"Characteristics of fiber-optic radiation sensor for passive scattering proton beams","volume":"12","author":"Son","year":"2017","journal-title":"Journal of Instrumentation"},{"key":"b9cc1c47462464f7e02ed5e2d2e660b30","doi-asserted-by":"publisher","DOI":"10.1088\/1748-0221\/13\/05\/P05030","article-title":"A Prototype Scintillating Fibre Beam Profile Monitor for Ion Therapy Beams","volume":"13","author":"Leverington","year":"2018","journal-title":"JINST"},{"key":"b819d26e4979affe305cd602692a93d0c","doi-asserted-by":"publisher","DOI":"10.1088\/1748-0221\/16\/02\/P02028","article-title":"Characterization of a beam-tagging hodoscope for hadrontherapy monitoring","volume":"16","author":"Allegrini","year":"2021","journal-title":"JINST"},{"key":"b47c6d5c4d9fa3303839cec5a5d59fad4","doi-asserted-by":"publisher","first-page":"e75","DOI":"10.1016\/j.ijrobp.2021.09.002","article-title":"Accurate Dosimetry for Radiobiology","volume":"111","author":"DeWerd","year":"2021","journal-title":"International Journal of Radiation Oncology*Biology*Physics"},{"key":"b8082402f5ef7768041ab673cf13b2db8","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.rpor.2014.10.006","article-title":"Microdosimetry: Principles and applications","volume":"21","author":"Santa Cruz","year":"2016","journal-title":"Reports of Practical Oncology amp; Radiotherapy"},{"key":"bcc02a9c03c0f09f3679a6feac9b228f6","doi-asserted-by":"publisher","first-page":"1364","DOI":"10.1002\/mp.14002","article-title":"High spatial resolution inorganic scintillator detector for high-energy X-ray beam at small field irradiation","volume":"47","author":"Debnath","year":"2020","journal-title":"Medical Physics"},{"key":"b37e2a166d3ab28426a1d1a481d356d33","doi-asserted-by":"publisher","first-page":"4912","DOI":"10.1002\/mp.15649","article-title":"Ultra-high dose rate dosimetry: Challenges and opportunities for FLASH radiation therapy","volume":"49","author":"Romano","year":"2022","journal-title":"Medical Physics"},{"key":"b5e9a3fa45975b4198f14d5bbba75e69e","doi-asserted-by":"publisher","first-page":"512","DOI":"10.3390\/s23010512","article-title":"Evaluation of a New Real-Time Dosimeter Sensor for Interventional Radiology Staff","volume":"23","author":"Hattori","year":"2023","journal-title":"Sensors"},{"key":"baf55e3d2558ed696f411b7f32988f970","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1093\/oxfordjournals.rpd.a005908","article-title":"Main Dosimetric Characteristics of Some Tissue-equivalent TL Detectors","volume":"100","author":"Miljanic","year":"2002","journal-title":"Radiation Protection Dosimetry"},{"key":"bcb7d1994d19a85fade2bdaedb5dc4083","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1364\/josa.66.000216","article-title":"Curvature loss formula for optical fibers","volume":"66","author":"Marcuse","year":"1976","journal-title":"Journal of the Optical Society of America"},{"key":"b11ef0fcf830550e066842192de7b494e","doi-asserted-by":"publisher","first-page":"039","DOI":"10.22323\/1.380.0039","article-title":"Characterization and functional test of a micro dosimeter of scintillating optical fibers","volume":"PANIC2021","author":"Santos","year":"2022","journal-title":"PoS"},{"article-title":"The aluminization of 600 k WLS fibers for the TileCal\/ATLAS\/LHC","author":"Saraiva","key":"b1ac082f75aeec12571cb128aa70ec5f4","doi-asserted-by":"crossref","DOI":"10.1109\/NSSMIC.2003.1352659"},{"key":"b14d4db6f4fb5f3ca8c203e2a9378eed9"},{"key":"b67ef4f44837d2f3fa5aef528f8a27e17","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nature Methods"},{"key":"bd6dd9b764d5c1fb57d4c16b16b386f25","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1109\/tsmc.1979.4310076","article-title":"A Threshold Selection Method from Gray-Level Histograms","volume":"9","author":"Otsu","year":"1979","journal-title":"IEEE Trans. Syst. Man Cybern."},{"key":"b859b00aec8885efc83d1541b52a1220d","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1109\/34.3918","article-title":"Efficient component labeling of images of arbitrary dimension represented by linear bintrees","volume":"10","author":"Samet","year":"1988","journal-title":"IEEE Transactions on Pattern Analysis and Machine Intelligence"},{"key":"b0b2cc82e6a177b18faefd88581b8597d"},{"key":"bf32d2c8c67d9a5d6c12cb68f25867a14"},{"key":"bb23c8a24ba39183be810274f5be972cf","doi-asserted-by":"publisher","DOI":"10.1016\/j.nima.2023.168471","article-title":"The design of nuclear front-end electronics based on MOSFET transistor used for radiation spectrometer","volume":"1055","author":"Wu","year":"2023","journal-title":"Nucl. Instrum. Meth. A"},{"key":"b1c21d9b19298645fa2534d9828ee0778","doi-asserted-by":"publisher","DOI":"10.1002\/admt.202000696","article-title":"Full-Inorganic Micro-Fiber Probe for Real-Time Radiation Monitoring","volume":"6","author":"Lv","year":"2020","journal-title":"Advanced Materials Technologies"},{"key":"bc7eb2b7f6e7b2eecfc146fa524ba6f0c","doi-asserted-by":"publisher","first-page":"2890","DOI":"10.1016\/j.biomaterials.2005.12.009","article-title":"Control of cell adhesion on poly(methyl methacrylate)","volume":"27","author":"Patel","year":"2006","journal-title":"Biomaterials"},{"key":"b1be5f8638bdcdf8d0f8534267baa57b5","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1163\/156856207781034124","article-title":"Plasma modification of PMMA films: surface free energy and cell-attachment studies","volume":"18","author":"Ozcan","year":"2007","journal-title":"Journal of Biomaterials Science, Polymer Edition"},{"key":"b149342f6f8c0a4fa233453690ede66ab","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1089\/ten.tec.2021.0069","article-title":"Pigmented Full-Thickness Human Skin Model Based on a Fibroblast-Derived Matrix for Long-Term Studies","volume":"27","author":"Zoio","year":"2021","journal-title":"Tissue Engineering Part C: Methods"},{"key":"b24d2e225dd943d243dc272389c9bfa34","doi-asserted-by":"publisher","first-page":"191","DOI":"10.3390\/micro2010013","article-title":"Biomimetic Full-Thickness Skin-on-a-Chip Based on a Fibroblast-Derived Matrix","volume":"2","author":"Zoio","year":"2022","journal-title":"Micro"}],"container-title":["Journal of Instrumentation"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-0221\/19\/05\/P05006","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-0221\/19\/05\/P05006\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-0221\/19\/05\/P05006\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-0221\/19\/05\/P05006\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T17:33:26Z","timestamp":1715103206000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-0221\/19\/05\/P05006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,1]]},"references-count":55,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2024,5,7]]},"published-print":{"date-parts":[[2024,5,1]]}},"URL":"https:\/\/doi.org\/10.1088\/1748-0221\/19\/05\/p05006","relation":{},"ISSN":["1748-0221"],"issn-type":[{"type":"electronic","value":"1748-0221"}],"subject":[],"published":{"date-parts":[[2024,5,1]]},"assertion":[{"value":"Development of a plastic scintillating optical fibers array dosimeter for radiobiology","name":"article_title","label":"Article Title"},{"value":"Journal of Instrumentation","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2024 IOP Publishing Ltd and Sissa Medialab","name":"copyright_information","label":"Copyright Information"},{"value":"2023-11-13","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-03-25","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-05-07","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}