{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T22:41:13Z","timestamp":1770763273509,"version":"3.50.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2001,12,1]],"date-time":"2001-12-01T00:00:00Z","timestamp":1007164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:p>\n                    Antibiotic use and antimicrobial resistance was compared between Vilnius and Huddinge University hospitals. Drug use data were expressed in number of defined daily doses\/100 bed-days; antimicrobial resistance\n         were given as percentages of resistant isolates. Thirty-five and 48 different antibiotic drugs were used in Vilnius and Huddinge, respectively. The overall consumption of antibiotics was 15 DDD\/100 bed-days\n         in Vilnius and 43 DDD\/100 bed-days in Huddinge. Benzylpenicillin, ampicillin, and aminoglycosides were the major antibiotics in Vilnius;\n                    <jats:italic toggle=\"yes\">\u03b2<\/jats:italic>\n                    -lactamase-resistant penicillins, cefalosporins, and\n         quinolones in Huddinge. In Vilnius, gentamicin made up one-quarter of the use.\n                    <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                    and Gram-negative isolates from wounds and blood were more resistant to gentamicin in Vilnius.\n                    <jats:italic toggle=\"yes\">S. aureus<\/jats:italic>\n                    was more often methicillin resistant in Vilnius than in Huddinge. There was no\n                    <jats:italic toggle=\"yes\">S. aureus<\/jats:italic>\n                    -resistant to vancomycin in either hospital. The vancomycin-resistant enterococci made up\n         from 4% to 10% in Vilnius hospital, but they were not detected in Huddinge hospital (0%). The majority of\n                    <jats:italic toggle=\"yes\">Streptococcus pneumoniae<\/jats:italic>\n                    isolates were sensitive to benzylpenicillin in both hospitals. The\n         higher resistance of microorganisms to some antibiotics in Vilnius may be explained by heavy use of few antibiotics. Lower level of hygiene procedures, sampling bias, and other methodological issues may\n         also have contributed. Guidelines for antibiotic use and hygienic procedures are now under development in Vilnius.\n                  <\/jats:p>","DOI":"10.1089\/10766290152773392","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T18:08:35Z","timestamp":1027706915000},"page":"383-389","source":"Crossref","is-referenced-by-count":17,"title":["Marked Differences in Antibiotic Use and Resistance Between University Hospitals in Vilnius, Lithuania, and Huddinge, Sweden"],"prefix":"10.1177","volume":"7","author":[{"given":"Jolanta","family":"Gulbinovi\u010d","sequence":"first","affiliation":[{"name":"Vilnius University, Department of Cardiology, Vilnius, Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl-Eric","family":"Myrb\u00e4ck","sequence":"additional","affiliation":[{"name":"Department of Clinical Bacteriology and Infection Control, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u016brat\u011b","family":"Bytautien\u011b","sequence":"additional","affiliation":[{"name":"Centre of Laboratory Medicine, Vilnius University Hospital Santari\u0161kiu klinikos, Vilnius, Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bj\u00f6rn","family":"Wettermark","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Huddinge University Hospital, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan","family":"Struwe","sequence":"additional","affiliation":[{"name":"Department of Clinical Bacteriology and Infection Control, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Bergman","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences &amp; Technology, Division of Clinical Pharmacology, Karolinska Institutet, WHO Collaborating Centre for Drug Utilisation Research and Clinical Pharmacological Services, Huddinge University Hospital, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2001,12]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/10766290152773392","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/10766290152773392","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:13:58Z","timestamp":1770747238000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/10766290152773392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["10.1089\/10766290152773392"],"URL":"https:\/\/doi.org\/10.1089\/10766290152773392","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12]]}}}