{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T12:44:07Z","timestamp":1782391447292,"version":"3.54.5"},"reference-count":0,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2003,10,1]],"date-time":"2003-10-01T00:00:00Z","timestamp":1064966400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:p>Vancomycin-resistant enterococci (VRE) have become important causes of nosocomial infections. This study evaluated the association between a variety of intravenous antimicrobial exposures and the isolation\n         of VRE using two control groups: (1) a vancomycin-susceptible enterococci (VSE) group, to assess factors associated with development of VRE, and (2) a nonenterococci control group, to assess factors associated\n         with positive cultures for enterococci without regard to vancomycin resistance. After adjusting for the effect of other antimicrobials, time at risk, and patient morbidity, compared to vancomycin-susceptible\n         enterococci controls, exposures to imipenem (OR = 4.9, 95% CI = 1.6\u201314.1) and ceftazidime (OR = 2.6, 95% CI = 1.1\u20136.1) were significant predictors of VRE. When compared to nonenterococci\n         controls, exposures to ampicillin (OR = 20.1, 95% CI = 1.5\u2013263.1) and imipenem (OR = 5.1, 95% CI = 1.5\u201317.1) were significantly associated with VRE. Neither piperacillin nor vancomycin\n         was associated with VRE compared to either control group. This study offers further evidence that the replacement of broad-spectrum cephalosporins by extended-spectrum penicillins, specifically piperacillin,\n         may be effective in reducing VRE.<\/jats:p>","DOI":"10.1089\/107662903322541928","type":"journal-article","created":{"date-parts":[[2003,11,10]],"date-time":"2003-11-10T17:05:49Z","timestamp":1068483949000},"page":"69-77","source":"Crossref","is-referenced-by-count":20,"title":["Association Between Antecedent Intravenous Antimicrobial Exposure and Isolation of Vancomycin-Resistant Enterococci"],"prefix":"10.1177","volume":"9","author":[{"given":"L.S.","family":"Chavers","sequence":"first","affiliation":[{"name":"Department of Epidemiology and International Health, University of Alabama at Birmingham, Birmingham, AL 35249."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.A.","family":"Moser","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Funkhouser","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and International Health, University of Alabama at Birmingham, Birmingham, AL 35249."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"W.H.","family":"Benjamin","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Chavers","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and International Health, University of Alabama at Birmingham, Birmingham, AL 35249."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"Stamm","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35249"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.B.","family":"Waites","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2003,10]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/107662903322541928","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/107662903322541928","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:14:14Z","timestamp":1770747254000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/107662903322541928"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,10]]},"references-count":0,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[2003,10]]}},"alternative-id":["10.1089\/107662903322541928"],"URL":"https:\/\/doi.org\/10.1089\/107662903322541928","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,10]]}}}