{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T21:30:26Z","timestamp":1770759026582,"version":"3.50.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2003,6,1]],"date-time":"2003-06-01T00:00:00Z","timestamp":1054425600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2003,6]]},"abstract":"<jats:p>\n                    To assess the nature and diversity of various types of SHV and TEM derivatives in our hospital a survey was conducted. Sixty-seven extended-spectrum\n                    <jats:italic toggle=\"yes\">\u03b2<\/jats:italic>\n                    -lactamases (ESBL)-producing nosocomial\n         pathogens, isolated over a 12-month period, were analyzed by means of PCR and direct sequencing. SHV-5 was the predominant ESBL found in our region (38 strains). Other less frequent variants included SHV-2\n         and SHV-12 with two and three isolates, respectively. For the first time, an outbreak of 11\n                    <jats:italic toggle=\"yes\">Pseudomonas aeruginosa<\/jats:italic>\n                    producing SHV-5 was encountered. All bla\n                    <jats:sub>TEM<\/jats:sub>\n                    -positive strains carried the\n         non-ESBL TEM-1. The incidence of non-SHV non-TEM ESBLs was remarkably high as almost one out of three isolates harbored such an ESBL. The epidemiological and clinical impact of these findings must be carefully\n         investigated and interpreted.\n                  <\/jats:p>","DOI":"10.1089\/107662903765826750","type":"journal-article","created":{"date-parts":[[2003,6,13]],"date-time":"2003-06-13T17:11:31Z","timestamp":1055524291000},"page":"161-165","source":"Crossref","is-referenced-by-count":12,"title":["Molecular Epidemiology of Extended-Spectrum\n                    <i>\u03b2<\/i>\n                    -Lactamases Produced by Clinical Isolates in a University Hospital in Greece: Detection of SHV-5 in\n                    <i>Pseudomonas aeruginosa<\/i>\n                    and Prevalence          of SHV-12"],"prefix":"10.1177","volume":"9","author":[{"given":"Ioannis K.","family":"Neonakis","sequence":"first","affiliation":[{"name":"Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, Faculty of Medicine, University of Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efstathia V.","family":"Scoulica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sevasti K.","family":"Dimitriou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achilleas I.","family":"Gikas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yannis J.","family":"Tselentis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2003,6]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/107662903765826750","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/107662903765826750","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:14:16Z","timestamp":1770747256000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/107662903765826750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,6]]}},"alternative-id":["10.1089\/107662903765826750"],"URL":"https:\/\/doi.org\/10.1089\/107662903765826750","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6]]}}}