{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T07:05:29Z","timestamp":1779433529521,"version":"3.53.1"},"reference-count":28,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Alternative and Complementary Medicine: Paradigm, Practice, and Policy Advancing Integrative Health"],"published-print":{"date-parts":[[2016,7]]},"abstract":"\n Objectives:<\/jats:title>\n \n The aim of this study was to evaluate the safety and the effect of\n dangguijagyag-san<\/jats:italic>\n (DJS) on mild cognitive impairment (MCI).\n <\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n This study examined the administration of DJS (\n \n ; angelica and peony formula) and was conducted at Uijeongbu Health Center in Gyeonggi-do, Korea, in 2013. Ninety-five of 118 patients diagnosed with MCI were followed up for 1 year after the study ended, and their medical records were analyzed.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n The patients included 36 men (37.9%) and 59 women (62.1%). When the results from before the study began were compared with the results 1 year after the study ended, the overall average score according to the Korean-Montreal Cognitive Assessment (K-MOCA) showed a statistically significant increase, from 15.46\u2009\u00b1\u20095.30 to 18.54\u2009\u00b1\u20095.11, respectively. Both male and female patients recorded a significant increase in K-MOCA scores for all sections, including the visuospatial\/executive section, the naming section, the attention section, the language section, the abstraction section, the delayed recall section, and the orientation section. Scores assessed by the Mini-Mental State Examination for Dementia Screening (MMSE-DS) showed a statistically significant increase, from 21.84\u2009\u00b1\u20093.59 before the study to 24.43\u2009\u00b1\u20093.13 after the study, but decreased slightly to 23.04\u2009\u00b1\u20093.36 at the 1-year follow-up. However, MMSE-DS scores measured before the study began increased significantly when compared with scores measured 1 year after the study ended.<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n DGJYS improved the cognitive skills of patients diagnosed with MCI, and no adverse effects were observed. In the future, the efficacy of DGJYS must be objectively verified by using a randomized controlled trial.<\/jats:p>\n <\/jats:sec>","DOI":"10.1089\/acm.2015.0261","type":"journal-article","created":{"date-parts":[[2016,5,20]],"date-time":"2016-05-20T02:24:30Z","timestamp":1463711070000},"page":"509-514","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["The Effect of\n Dangguijagyag-san<\/i>\n on Mild Cognitive Impairment"],"prefix":"10.1177","volume":"22","author":[{"given":"Kyeong Han","family":"Kim","sequence":"first","affiliation":[{"name":"Korea Health Promotion Foundation"},{"name":"Kyung Hee University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho-Yeon","family":"Go","sequence":"additional","affiliation":[{"name":"Semyung University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju Ah","family":"Lee","sequence":"additional","affiliation":[{"name":"Korea Institute of Oriental Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiae","family":"Choi","sequence":"additional","affiliation":[{"name":"Korea Institute of Oriental Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunju","family":"Park","sequence":"additional","affiliation":[{"name":"Daejeon University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myeong Soo","family":"Lee","sequence":"additional","affiliation":[{"name":"Korea Institute of Oriental Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong-Gyu","family":"Ko","sequence":"additional","affiliation":[{"name":"Kyung Hee University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,7,1]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Song CY Park BK. 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