{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:48:30Z","timestamp":1783471710272,"version":"3.55.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Medical Acupuncture"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>\n                      A complementary treatment for managing chemotherapy-induced nausea and vomiting (CINV) with promising results is electrostimulation of Pericardium 6 (PC 6;\n                      <jats:italic toggle=\"yes\">Neiguan<\/jats:italic>\n                      ). This review was conducted to evaluate the effects of electrostimulation therapy at PC 6 to control CINV in patients with cancer. The review was registered on PROSPERO (CRD42018087753).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This systematic review and meta-analysis of clinical trials was accomplished according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Studies written in English, Portuguese, or Spanish that met the eligibility criteria organized according to the PICO [Patient, Problem or Population; Intervention; Comparison, Control, or comparator; Outcome(s)] anagram were included. Descriptors used to search the databases were identified and selected according to the Medical Subject Headings of the National Library of Medicine. The primary outcomes evaluated were the frequency and severity of nausea, vomiting, and general emesis after the experimental protocol. The secondary outcomes evaluated were the numbers of antiemetic pills taken and the patients' quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Fourteen articles were included. There was a reduction in the mean number of episodes of acute nausea (mean difference [MD]\u2009=\u2009\u22122.08; 95% confidence interval [95%CI]\u2009=\u2009\u22122.76, \u22121.39) and acute vomiting (MD\u2009=\u2009\u22120.91; 95% CI\u2009=\u2009\u22121.39, \u22120.42) or delayed (MD\u2009=\u2009\u22120.85; 95%CI\u2009=\u2009\u22121.47, \u22120.23) in patients given the treatment. The other analyses of nausea, vomiting and emesis showed no differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Electrostimulation at PC6 has an effect on controlling general emesis, and acute nausea and vomiting in different phases of recovery from chemotherapy in patients with cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/acu.2020.1431","type":"journal-article","created":{"date-parts":[[2020,12,21]],"date-time":"2020-12-21T16:59:45Z","timestamp":1608569985000},"page":"22-44","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Electrical Stimulation of PC 6 to Control Chemotherapy-Induced Nausea and Vomiting in Patients with Cancer: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"33","author":[{"given":"Gabriel Tavares","family":"Garcia","sequence":"first","affiliation":[{"name":"Federal University of Par\u00e1 (UFPA), Bel\u00e9m, PA, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robson Fonseca","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Federal University of Par\u00e1 (UFPA), Bel\u00e9m, PA, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella Boechat","family":"Faria Santos","sequence":"additional","affiliation":[{"name":"Federal University of Par\u00e1 (UFPA), Bel\u00e9m, PA, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiana de Campos","family":"Gomes","sequence":"additional","affiliation":[{"name":"School of Medicine of S\u00e3o Jos\u00e9 do Rio Preto (FAMERP), S\u00e3o Jos\u00e9 do Rio Preto, SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Sim\u00e3o de","family":"Melo-Neto","sequence":"additional","affiliation":[{"name":"Federal University of Par\u00e1 (UFPA), Bel\u00e9m, PA, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,2,16]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2017.02.017"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdv138"},{"issue":"5","key":"e_1_3_3_4_2","first-page":"1661","article-title":"Prevention of chemotherapy-induced nausea: The role of neurokinin-1 (NK1) receptor antagonists","volume":"25","author":"Bo\u0161njak SM","year":"2017","unstructured":"Bo\u0161njak SM, , Gralla RJ, , Schwartzberg L. 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