{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:15:59Z","timestamp":1777518959383,"version":"3.51.4"},"reference-count":39,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Medical Acupuncture"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Fibromyalgia is a chronic illness that causes symptoms such as pain. In Japan, although pregabalin and duloxetine are the drugs of choice for fibromyalgia, they may be ineffective or may cause side-effects. Studies have reported on the efficacy of acupuncture against fibromyalgia. However, acupuncture is not always effective in clinical practice, and the reason for this is thought to be the dysfunction of the descending pain control system. This study aimed to determine whether the combined use of electro-scalp acupuncture and conventional electroacupuncture reduces fibromyalgia symptoms and drug dosage requirements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients with intractable fibromyalgia (visual analog scale [VAS] score \u226550\u2009mm; Japanese version of the Fibromyalgia Impact Questionnaire [JFIQ] score \u226550) receiving pregabalin were recruited in this single-arm nonrandomized uncontrolled study. They underwent electroacupuncture on four limbs plus electro-scalp acupuncture once a week for 5 weeks. Drug intake, pain (as determined using VAS), quality of life (QOL; as determined using JFIQ), anxiety, depression, catastrophic thoughts, and sleep were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Although there was no increase in drug intake, 42.8% (3\/7) of patients reduced pregabalin intake by approximately 10% (a moderate though insignificant effect). Pain levels significantly declined (VAS 75.4\u2009\u00b1\u200911.7\u2009mm to 64.3\u2009\u00b1\u200917.3\u2009mm;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.05) and QOL significantly improved (JFIQ 67.0\u2009\u00b1\u200913.4 to 50.9\u2009\u00b1\u200918.3;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.02). The parameters for anxiety, depression, catastrophic thoughts, and sleep did not significantly change.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The combination of conventional electroacupuncture plus electro-scalp acupuncture may effectively alleviate pain, improve QOL, and reduce pregabalin dosage requirements in patients with fibromyalgia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/acu.2022.0005","type":"journal-article","created":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T12:09:21Z","timestamp":1655467761000},"page":"193-200","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Effects of Acupuncture Therapy on Drug-Resistant Fibromyalgia: An Exploratory Single-Arm Nonrandomized Trial"],"prefix":"10.1177","volume":"34","author":[{"given":"Yoichi","family":"Minakawa","sequence":"first","affiliation":[{"name":"Acupuncture and Moxibustion, Faculty of Health Care, Teikyo Heisei University, Tokyo, Japan."},{"name":"Research Institute of Oriental Medicine, Teikyo Heisei University, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Saito","sequence":"additional","affiliation":[{"name":"Acupuncture and Moxibustion, Heisei-iyo College of Medical Technologies, Osaka, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshifuji","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"The Division of Rheumatology, Kuwana City Medical Center, Mie, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Oka","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Tokyo Yaesu Clinic, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Miki","sequence":"additional","affiliation":[{"name":"Faculty of Health Science, Osaka Yukioka College of Health Science, Osaka, Japan."},{"name":"Center for Pain Management, Hayaishi Hospital, Osaka, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masao","family":"Yukioka","sequence":"additional","affiliation":[{"name":"Faculty of Health Science, Osaka Yukioka College of Health Science, Osaka, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0078-3634","authenticated-orcid":false,"given":"Kazunori","family":"Itoh","sequence":"additional","affiliation":[{"name":"Department of Clinical Acupuncture and Moxibustion, Meiji University of Integrative Medicine, Kyoto, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,6,16]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780330203"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-013-0356-5"},{"key":"e_1_3_5_4_2","first-page":"87","article-title":"A nationwide epidemiological survey for patients with fibromyalgia in Japan","volume":"18","author":"Matsumoto Y","year":"2006","unstructured":"Matsumoto Y, , Maeda S, , Tamakoshi A, , Nishioka K. 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