{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:26:43Z","timestamp":1780104403807,"version":"3.54.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2008,6]]},"abstract":"<jats:p>\n                    Oral lesions (OL) have an important prognostic value for HIV\/AIDS patients. However, the behavior of OL in HIV\/AIDS patients undergoing highly active antiretroviral therapy including efavirenz (HAART\/EFV) has not been documented. Our objective was to establish the prevalence of OL in HIV\/AIDS patients undergoing HAART\/EFV and to compare it with the prevalence of OL in patients undergoing antiretroviral therapy including a protease inhibitor (HAART\/PI). Seventy-three HIV\/AIDS patients undergoing antiretroviral treatment for at least for 6 months at \u201cLa Raza\u201d Medical Center's Internal Medicine Unit (IMSS, Mexico City) were included. To detect OL, a detailed examination of oral soft tissues was performed in each patient. Patient records recorded gender, seropositivity time, route of contagion, antiretroviral therapy type and duration, CD4 lymphocyte count\/ml, and viral load. Two groups were formed: 38 patients receiving HAART\/EFV [two nucleoside analogue reverse transcriptase inhibitors (NARTI) plus efavirenz] and 35 patients receiving HAART\/PI (two NARTIs plus one PI). OL prevalence was established in each study group. The Chi-square test was applied (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.05\n                    <jats:sub>IC95%<\/jats:sub>\n                    ). OL prevalence in the HAART\/EFV group (32%) was lower (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.007) than in the HAART\/PI group (63%). Candidosis was the most prevalent OL in both groups. Herpes labialis, HIV-associated necrotizing periodontitis, xerostomia, hairy leukoplakia, and nonspecific oral sores were identified. The highest prevalence for all OL was found in the HAART\/PI group. These findings suggest that HIV\/AIDS patients undergoing HAART\/EFV show a lower prevalence of oral lesions than patients undergoing HAART\/PI.\n                  <\/jats:p>","DOI":"10.1089\/aid.2007.0159","type":"journal-article","created":{"date-parts":[[2008,5,28]],"date-time":"2008-05-28T15:57:00Z","timestamp":1211990220000},"page":"815-820","source":"Crossref","is-referenced-by-count":13,"title":["<i>Short Communication:<\/i>\n                    Oral Lesions in HIV\/AIDS Patients Undergoing HAART Including Efavirenz"],"prefix":"10.1177","volume":"24","author":[{"given":"S.I.","family":"Aquino-Garc\u00eda","sequence":"first","affiliation":[{"name":"Laboratorio de Patolog\u00eda Cl\u00ednica y Experimental, Divisi\u00f3n de Estudios de Postgrado e Investigaci\u00f3n, Facultad de Odontolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, M\u00e9xico City, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"Rivas","sequence":"additional","affiliation":[{"name":"Cl\u00ednica de Medicina Interna, Centro M\u00e9dico \u201cLa Raza,\u201d Instituto Mexicano del Seguro Social, M\u00e9xico City, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Ceballos-Salobre\u00f1a","sequence":"additional","affiliation":[{"name":"Facultad de Odontolog\u00eda, Universidad de Granada, Granada, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.E.","family":"Acosta-Gio","sequence":"additional","affiliation":[{"name":"Laboratorio de Microbiolog\u00eda y Control de Infecciones, Divisi\u00f3n de Estudios de Postgrado e Investigaci\u00f3n, Facultad de Odontolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, M\u00e9xico City, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.A.","family":"Gait\u00e1n-Cepeda","sequence":"additional","affiliation":[{"name":"Laboratorio de Patolog\u00eda Cl\u00ednica y Experimental, Divisi\u00f3n de Estudios de Postgrado e Investigaci\u00f3n, Facultad de Odontolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, M\u00e9xico City, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2008,6,1]]},"container-title":["AIDS Research and Human Retroviruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2007.0159","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2007.0159","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:11:02Z","timestamp":1777367462000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/aid.2007.0159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["10.1089\/aid.2007.0159"],"URL":"https:\/\/doi.org\/10.1089\/aid.2007.0159","relation":{},"ISSN":["0889-2229","1931-8405"],"issn-type":[{"value":"0889-2229","type":"print"},{"value":"1931-8405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,6]]}}}