{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T12:09:06Z","timestamp":1779106146838,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:p>\n                    Chronic HIV-1 infection results in the expansion of both NKG2C\n                    <jats:sup>+<\/jats:sup>\n                    and CD16\n                    <jats:sup>+<\/jats:sup>\n                    CD56\n                    <jats:sup>\u2212<\/jats:sup>\n                    human natural killer cells. NKG2C\n                    <jats:sup>+<\/jats:sup>\n                    cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56\n                    <jats:sup>\u2212<\/jats:sup>\n                    CD16\n                    <jats:sup>+<\/jats:sup>\n                    natural killer (NK) cells is associated with HIV-1 viremia. Here we report an association between increased proportions of CD56\n                    <jats:sup>\u2212<\/jats:sup>\n                    CD16\n                    <jats:sup>+<\/jats:sup>\n                    NK cells in viremic HIV-1\n                    <jats:sup>+<\/jats:sup>\n                    individuals and an increased contribution of NKG2C\n                    <jats:sup>+<\/jats:sup>\n                    cells to this subset. These data, in addition to anti-HCMV IgG serology, indicate a potential contribution of both HCMV and HIV-1 to NK cell dysfunction in HIV-1-infected individuals.\n                  <\/jats:p>","DOI":"10.1089\/aid.2011.0397","type":"journal-article","created":{"date-parts":[[2012,8,24]],"date-time":"2012-08-24T23:43:26Z","timestamp":1345851806000},"page":"84-88","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Short Communication: NKG2C\n                    <sup>+<\/sup>\n                    NK Cells Contribute to Increases in CD16\n                    <sup>+<\/sup>\n                    CD56\n                    <sup>\u2212<\/sup>\n                    Cells in HIV Type 1\n                    <sup>+<\/sup>\n                    Individuals with High Plasma Viral Load"],"prefix":"10.1177","volume":"29","author":[{"given":"John N.S.","family":"Gregson","sequence":"first","affiliation":[{"name":"Chelsea and Westminster Hospital","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leticia","family":"Kuri-Cervantes","sequence":"additional","affiliation":[{"name":"Chelsea and Westminster Hospital","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher M.","family":"Mela","sequence":"additional","affiliation":[{"name":"Chelsea and Westminster Hospital","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian G.","family":"Gazzard","sequence":"additional","affiliation":[{"name":"Chelsea and Westminster Hospital","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Bower","sequence":"additional","affiliation":[{"name":"Chelsea and Westminster Hospital","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin 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