{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:44:13Z","timestamp":1777380253362,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:p>\n                    Dizziness is a symptom in human T cell lymphotropic virus type-associated myelopathy\/tropical spastic paraparesis (HAM\/TSP) and may occur due to vestibulospinal tract dysfunction. This tract can be assessed by an electrophysiological test called vestibular-evoked myogenic potential (VEMP). The aim was to correlate the result of VEMP generated by acoustic stimuli and dizziness in individuals with human T cell lymphotropic virus type 1 (HTLV-1)-asymptomatic infection and HAM\/TSP. VEMP was recorded from the sternocleidomastoid muscle of 60 HTLV-1-negative adults (60\u00b18 years) and 60 individuals infected with HTLV-1, 30 being asymptomatic (59\u00b18 years) and 30 with HAM\/TSP (59\u00b18 years). In all groups, 90% of the participants were women. VEMP was generated by acoustic stimuli (short tone bursts), with an intensity of 118 dBHL and band-pass filter from 10\u2009Hz to 1,500\u2009Hz, and presented 200 stimuli at a frequency of 1,000\u2009Hz with a record time of 60\u2009ms. Of 60 HTLV-1-negative individuals, 14 (23%) reported dizziness; VEMP was normal in all. In the HTLV-1-asymptomatic group, 11(37%) complained of dizziness (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    =0.31); VEMP was altered in four (40%) subjects with dizziness and in one (5%) without dizziness (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    =0.00). In the group with HAM\/TSP, dizziness was reported by 17 (57%) subjects (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    =0.002); VEMP was altered in 11 (64%) with dizziness and in 5 (38%) without dizziness (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    =0.15). Dizziness without an apparent etiology in HTLV-1-asymptomatic carriers deserves attention in terms of a possible subclinical spinal cord involvement that can be clarified through spinal electrophysiological tests. Damage of the vestibulospinal tract seems to occur in the early stages of HAM\/TSP.\n                  <\/jats:p>","DOI":"10.1089\/aid.2014.0153","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T09:33:29Z","timestamp":1426066409000},"page":"649-654","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Electrophysiological Analysis Shows Dizziness as the First Symptom in Human T Cell Lymphotropic Virus Type-Associated Myelopathy\/Tropical Spastic Paraparesis"],"prefix":"10.1177","volume":"31","author":[{"given":"Ludimila","family":"Labanca","sequence":"first","affiliation":[{"name":"Federal University of Minas Gerais","place":["Brazil"]},{"name":"Interdisciplinary HTLV Research Group (GIPH)","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana L\u00facia Borges","family":"Starling","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais","place":["Brazil"]},{"name":"Interdisciplinary HTLV Research Group (GIPH)","place":["Brazil"]},{"name":"Minas Gerais State Center of Hematology and Blood Transfusion (Funda\u00e7\u00e3o Hemominas)","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvio Roberto","family":"de Sousa-Pereira","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Cl\u00e1udio Ferreira","family":"Romanelli","sequence":"additional","affiliation":[{"name":"Interdisciplinary HTLV Research Group (GIPH)","place":["Brazil"]},{"name":"Minas Gerais State Center of Hematology and Blood Transfusion (Funda\u00e7\u00e3o Hemominas)","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna B\u00e1rbara","family":"de Freitas Carneiro-Proietti","sequence":"additional","affiliation":[{"name":"Interdisciplinary HTLV Research Group (GIPH)","place":["Brazil"]},{"name":"Minas Gerais State Center of Hematology and Blood Transfusion (Funda\u00e7\u00e3o Hemominas)","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas Novaes","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele Rosa","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise","family":"Utsch Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais","place":["Brazil"]},{"name":"Interdisciplinary HTLV Research Group (GIPH)","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,6,1]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"1010","article-title":"Brain and spinal cord magnetic resonance imaging in spastic paraparesis associated to human T-lymphotropic virus","volume":"134","author":"Cervilla JO","year":"2006","unstructured":"Cervilla JO, , Cartier LR, , and Garcia LF: Brain and spinal cord magnetic resonance imaging in spastic paraparesis associated to human T-lymphotropic virus. 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