{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T12:09:44Z","timestamp":1779106184523,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:p>In this research, we reported a new second generation recombinant form (GXDY460B) between circulating recombinant form (CRF)01_AE and CRF07_BC in a seroconversion couple who obtained the virus from her husband by heterosexual behavior. The analysis result of the near full-length genomic characterization showed that the genome comprises at least 12 interlaced segments, including six CRF07_BC and six CRF01_AE segments, with CRF07_BC as the main framework. Cocirculation of multiple virus subtypes and multiple infection routes have existed for a long time in Guangxi, but the recombinant strain was rarely reported among heterosexual transmission population because of its lower crowd confounding degree than men who have sex with men and injecting drug user population. It is the first time that the unique recombinant form (URF) between CRF01_AE and CRF07_BC was identified among heterosexual transmission in Guangxi. The emergence of the novel recombinant helps to understand the pattern of the URF virus.<\/jats:p>","DOI":"10.1089\/aid.2015.0329","type":"journal-article","created":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T04:08:48Z","timestamp":1455854928000},"page":"689-693","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Near Full-Length Genomic Characterization of a Novel HIV Type 1 CRF01_AE\/CRF07_BC Recombinant Form Transmitted Between a Heterosexual Couple in Guangxi, China"],"prefix":"10.1177","volume":"32","author":[{"given":"Zhe","family":"Dong","sequence":"first","affiliation":[{"name":"Chinese Center for Disease Control and Prevention","place":["People's Republic of China"]},{"name":"Peking Union Medical College","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiyong","family":"Shen","sequence":"additional","affiliation":[{"name":"Guangxi Center for Disease Prevention and Control","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Runsong","family":"Xiong","sequence":"additional","affiliation":[{"name":"Guangxi Center for Disease Prevention and Control","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuxiong","family":"Liang","sequence":"additional","affiliation":[{"name":"Guangxi Center for Disease Prevention and Control","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shujia","family":"Liang","sequence":"additional","affiliation":[{"name":"Guangxi Center for Disease Prevention and Control","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianjun","family":"Li","sequence":"additional","affiliation":[{"name":"Guangxi Center for Disease Prevention and Control","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangjie","family":"Tan","sequence":"additional","affiliation":[{"name":"Guangxi Center for Disease Prevention and Control","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"He","family":"Jiang","sequence":"additional","affiliation":[{"name":"Guangxi Center for Disease Prevention and Control","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyi","family":"Yang","sequence":"additional","affiliation":[{"name":"Guangxi Center for Disease Prevention and Control","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Li","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingjie","family":"Liao","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiming","family":"Shao","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention","place":["People's Republic of China"]},{"name":"Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Feng","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuying","family":"Zhu","sequence":"additional","affiliation":[{"name":"Guangxi Center for Disease Prevention and Control","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047289"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2013.0234"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2013.0134"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2009.0002"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0030443"},{"key":"e_1_3_3_7_2","first-page":"356","article-title":"Molecular epidemiology of HIV-1 subtypes in southern China","volume":"38","author":"Laeyendecker O","year":"2005","unstructured":"Laeyendecker O, , Zhang GT, , Garten R, et al.: Molecular epidemiology of HIV-1 subtypes in southern China. J Acquir Immune Defic Syndr, 2005; 38:356\u2013362.","journal-title":"J Acquir Immune Defic Syndr"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2011.0246"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00399-08"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2013.0230"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2006.04.009"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.1.152-160.1999"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msm092"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.23.11286-11295.2000"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1089\/088922299311754"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)92304-3"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)79316-8"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328360db2d"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.23360"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2006.01557.x"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2011.0364"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283522c97"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2013.0104"},{"key":"e_1_3_3_24_2","first-page":"109","article-title":"[The identification of recombinant HIV-1 strains in IDUs in southwest and northwest China]","volume":"13","author":"Shao Y","year":"1999","unstructured":"Shao Y, , Zhao F, , Yang W: [The identification of recombinant HIV-1 strains in IDUs in southwest and northwest China]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi, 1999; 13:109\u2013112.","journal-title":"Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2013.0116"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2014.0307"}],"container-title":["AIDS Research and Human Retroviruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2015.0329","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/aid.2015.0329","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2015.0329","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T11:15:04Z","timestamp":1779102904000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/aid.2015.0329"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1089\/aid.2015.0329"],"URL":"https:\/\/doi.org\/10.1089\/aid.2015.0329","relation":{},"ISSN":["0889-2229","1931-8405"],"issn-type":[{"value":"0889-2229","type":"print"},{"value":"1931-8405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7]]}}}