{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:48:15Z","timestamp":1777380495419,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>\n                    In attempt to identify the factors associated with delayed diagnosis during HIV infection, we studied retrospectively the epidemiological profile of HIV-infected patients diagnosed between January 1, 2012 and December 31, 2013 and followed in our clinical center in Paris. Data were compared to those obtained at the same site during the year 2003. One hundred eighty-six patients fulfilled the inclusion criteria: 49 (26%) had a CD4 count &lt;200\/mm\n                    <jats:sup>3<\/jats:sup>\n                    at diagnosis. Compared to subjects with CD4 count \u2265200\/mm\n                    <jats:sup>3<\/jats:sup>\n                    , advanced patients were older, had a higher plasma viral load, had more often an AIDS-defining event at the time of HIV diagnosis (45% vs. 3%), had been infected more often through heterosexual contact (69% vs. 44%), had less frequently past HIV testing (23% vs. 63%), and tended to live in less favorable conditions. A higher proportion of these patients initiated antiretroviral therapy in the 3 months following diagnosis (93.9% vs. 48.1%). Compared to data obtained in 161 patients in 2003, the proportions of advanced patients were similar between the two periods (26% vs. 22%). There was a significant increase from year 2003 to the 2012\u20132013 period in the proportion of men who have sex with men (MSM) (50% vs. 27%) and in the percentage of patients infected with HIV-1 subtype B (48% vs. 27%) and with positive syphilis serology (22% vs. 8%). Our data show that (1) HIV screening should be extended to populations with the following characteristics: older age, heterosexuality, and low socioeconomic level, and (2) HIV transmission continues to progress in MSM, arguing for the value of preexposure prophylaxis.\n                  <\/jats:p>","DOI":"10.1089\/aid.2016.0036","type":"journal-article","created":{"date-parts":[[2016,7,31]],"date-time":"2016-07-31T23:13:54Z","timestamp":1470006834000},"page":"11-16","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Epidemiological Profile of Newly Diagnosed HIV-Infected Patients in Northern Paris: A Retrospective Study"],"prefix":"10.1177","volume":"33","author":[{"given":"Olivia","family":"Senard","sequence":"first","affiliation":[{"name":"Service de Maladies Infectieuses et Tropicales, AP-HP, H\u00f4pital Bichat-Claude Bernard, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Burdet","sequence":"additional","affiliation":[{"name":"IAME, UMR 1137, INSERM, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9, Service de Biostatistique, AP-HP, H\u00f4pital Bichat-Claude Bernard, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benoit","family":"Visseaux","sequence":"additional","affiliation":[{"name":"IAME, UMR 1137, INSERM, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9, Laboratoire de Virologie, H\u00f4pital Bichat, AP-HP, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Charpentier","sequence":"additional","affiliation":[{"name":"IAME, UMR 1137, INSERM, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9, Laboratoire de Virologie, H\u00f4pital Bichat, AP-HP, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvie","family":"Le Gac","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses et Tropicales, AP-HP, H\u00f4pital Bichat-Claude Bernard, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z\u00e9lie","family":"Julia","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses et Tropicales, AP-HP, H\u00f4pital Bichat-Claude Bernard, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvie","family":"Lariven","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses et Tropicales, AP-HP, H\u00f4pital Bichat-Claude Bernard, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane","family":"Descamps","sequence":"additional","affiliation":[{"name":"IAME, UMR 1137, INSERM, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9, Laboratoire de Virologie, H\u00f4pital Bichat, AP-HP, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yazdan","family":"Yazdanpanah","sequence":"additional","affiliation":[{"name":"IAME, UMR 1137, INSERM, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9, Service de Maladies Infectieuses et Tropicales, H\u00f4pital Bichat, AP-HP, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Yeni","sequence":"additional","affiliation":[{"name":"IAME, UMR 1137, INSERM, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9, Service de Maladies Infectieuses et Tropicales, H\u00f4pital Bichat, AP-HP, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00e9ronique","family":"Joly","sequence":"additional","affiliation":[{"name":"IAME, UMR 1137, INSERM, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9, Service de Maladies Infectieuses et Tropicales, H\u00f4pital Bichat, AP-HP, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,1,1]]},"reference":[{"key":"e_1_3_2_2_2","volume-title":"HIV\/AIDS Surveillance in Europe 2009","author":"European Centre for Disease Prevention and Control\/WHO Regional Office for Europe","year":"2010","unstructured":"European Centre for Disease Prevention and Control\/WHO Regional Office for Europe: HIV\/AIDS Surveillance in Europe 2009. 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