{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:29:41Z","timestamp":1777379381258,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:p>Sexual contact is the main route of transmission of HIV type 1 (HIV-1) pandemic in China. New unique recombinant forms (URFs) were increasingly characterized in sexual populations in recent years. We reported two URFs identified from two male HIV-1-positive patients who were infected through sexual exposure in Shaanxi, China. Phylogenetic analyses and bootscan analyses revealed that the near full-length genomes of the two URFs were having four recombinant breakpoints, with two CRF07_BC fragments inserted into CRF01_AE backbones. The CRF01_AE fragments of the two URFs clustered with previously reported a cluster 5 lineage of CRF01_AE. The four recombinant breakpoints of the two URFs were quite similar. The emergence of the new CRF01_AE\/07_BC URFs indicated the complexity genetic variability and the active epidemic of HIV-1. Much more attention should be paid to monitor the emergency of recombinant strains.<\/jats:p>","DOI":"10.1089\/aid.2018.0137","type":"journal-article","created":{"date-parts":[[2018,8,17]],"date-time":"2018-08-17T08:03:29Z","timestamp":1534493009000},"page":"191-195","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Identification of Two Novel HIV-1 Second-Generation Recombinant Forms (CRF01_AE\/07_BC) in Shaanxi, China"],"prefix":"10.1177","volume":"35","author":[{"given":"Mengyan","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of AIDS Prevention and Control, Shaanxi Provincial Center for Disease Prevention and Control, Xi'an, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruolei","family":"Xin","sequence":"additional","affiliation":[{"name":"Institute of STD\/AIDS Prevention and Control, Beijing Center for Disease Prevention and Control, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Li","sequence":"additional","affiliation":[{"name":"Department of AIDS Prevention and Control, Shaanxi Provincial Center for Disease Prevention and Control, Xi'an, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lifang","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of AIDS Prevention and Control, Shaanxi Provincial Center for Disease Prevention and Control, Xi'an, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenhui","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of AIDS Prevention and Control, Shaanxi Provincial Center for Disease Prevention and Control, Xi'an, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,2]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.22.11273-11282.2002"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2008.01.007"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2012.10.026"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph13010030"},{"key":"e_1_3_2_6_2","unstructured":"Shaanxi Health and Family Planning Commission: The news release for AIDS control progress in Shaanxi province in 2017. 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