{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:32:14Z","timestamp":1777379534164,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:p>\n                    Bali, the first province to report a case of HIV in 1987, was placed sixth among Indonesian provinces with the highest cumulative number of HIV cases in 2017. As a popular tourist destination, the spread of genetic variants of HIV through international travel may become a cause for concern in Bali. Tourism is mostly concentrated in south Bali; thus, HIV in less popular regions in north Bali, such as Buleleng Regency, may have viral characteristics different from that in south Bali. Forty-three protease (PR), 40 reverse transcriptase (RT), 27\n                    <jats:italic toggle=\"yes\">gag<\/jats:italic>\n                    , and 23\n                    <jats:italic toggle=\"yes\">env<\/jats:italic>\n                    genes were sequenced from 48 samples derived from antiretroviral treatment-experienced individuals. Subtyping revealed CRF01_AE as the dominant circulating recombinant form of HIV-1 in north Bali. Although no major mutation was detected in PR genes, several major mutations were identified in 4 out of the 40 RT genes (10%), indicating the emergence of HIV-1 drug resistance in this region.\n                  <\/jats:p>","DOI":"10.1089\/aid.2019.0058","type":"journal-article","created":{"date-parts":[[2019,4,19]],"date-time":"2019-04-19T07:51:32Z","timestamp":1555660292000},"page":"769-774","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Genotypic Characterization of Human Immunodeficiency Virus Type 1 Isolated from Antiretroviral Treatment-Experienced Individuals in Buleleng Regency, Bali, Indonesia"],"prefix":"10.1177","volume":"35","author":[{"given":"Ni Luh Ayu","family":"Megasari","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devi","family":"Oktafiani","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elsa Fitri","family":"Ana","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhei","family":"Ueda","sequence":"additional","affiliation":[{"name":"Indonesia-Japan Collaborative Research Centre for Emerging and Re-Emerging Infectious Diseases, Institute of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia."},{"name":"Department of Public Health, Kobe University Graduate School of Health Sciences, Hyogo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"Kotaki","sequence":"additional","affiliation":[{"name":"Department of Public Health, Kobe University Graduate School of Health Sciences, Hyogo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Nasronudin","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia."},{"name":"Indonesia-Japan Collaborative Research Centre for Emerging and Re-Emerging Infectious Diseases, Institute of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Soetjipto","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia."},{"name":"Indonesia-Japan Collaborative Research Centre for Emerging and Re-Emerging Infectious Diseases, Institute of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Kameoka","sequence":"additional","affiliation":[{"name":"Department of Public Health, Kobe University Graduate School of Health Sciences, Hyogo, Japan."},{"name":"Center for Infectious Diseases, Kobe University Graduate School of Medicine, Hyogo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,8]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Joint United Nations Programme on HIV\/AIDS (UNAIDS): UNAIDS Data 2018. 2018. Available at www.unaids.org\/sites\/default\/files\/media_asset\/unaids-data-2018_en.pdf accessed on February5 2019."},{"key":"e_1_3_3_3_2","unstructured":"Direktorat Jenderal Pencegahan dan Pengendalian Penyakit Kementerian Kesehatan RI (Ditjen P2P Kemenkes RI): Laporan Situasi Perkembangan HIV-AIDS & PIMS di Indonesia Januari-Desember 2017. 2018. Available at http:\/\/siha.depkes.go.id\/portal\/files_upload\/Laporan_HIV_AIDS_TW_4_Tahun_2017__1_.pdf accessed on February5 2019."},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2011.12.001"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2014.0221"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2016.0054"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2018.0040"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.5114\/hivar.2018.76375"},{"key":"e_1_3_3_9_2","unstructured":"Kementerian Kesehatan Republik Indonesia (Kemenkes RI): Peraturan Menteri Kesehatan Republik Indonesia Nomor 87 Tahun 2014 tentang Pedoman Pengobatan Antiretroviral. 2015. Available at http:\/\/siha.depkes.go.id\/portal\/files_upload\/Buku_Permenkes_ARV_Cetak.pdf accessed on February5 2019."},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.25161"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70255-9"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(03)00484-5"},{"key":"e_1_3_3_13_2","first-page":"69","article-title":"Strategi Menuju Pariwisata Bali yang Berkualitas [Strategies towards excellent Bali tourism]","volume":"03","author":"Utama IGBR","year":"2013","unstructured":"Utama IGBR: Strategi Menuju Pariwisata Bali yang Berkualitas [Strategies towards excellent Bali tourism]. J Bali Stud, 2013; 03:69\u201390.","journal-title":"J Bali Stud"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.1995.11.1413"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.2202\/1544-6115.1680"},{"key":"e_1_3_3_16_2","first-page":"132","article-title":"2017 Update of drug resistance in HIV-1 infection","volume":"24","author":"Wensing AM","year":"2017","unstructured":"Wensing AM, , Calvez V, , Gunthard HF, et al.: 2017 Update of drug resistance in HIV-1 infection. Top Antivir Med, 2017; 24:132\u2013133.","journal-title":"Top Antivir Med"}],"container-title":["AIDS Research and Human Retroviruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/aid.2019.0058","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2019.0058","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2019.0058","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:14:42Z","timestamp":1777367682000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/aid.2019.0058"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1089\/aid.2019.0058"],"URL":"https:\/\/doi.org\/10.1089\/aid.2019.0058","relation":{},"ISSN":["0889-2229","1931-8405"],"issn-type":[{"value":"0889-2229","type":"print"},{"value":"1931-8405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8]]}}}