{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:09:33Z","timestamp":1787008173583,"version":"build-2736575974"},"reference-count":10,"publisher":"SAGE Publications","issue":"11-12","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:p>Life expectancy of HIV patients has increased over time. Older HIV patients have a higher frequency of noncommunicable diseases (NCD) than general population, and require multiple treatments. The main objective is to evaluate the changes in frequency of NCD and polypharmacy in HIV patients of three referral centers in Salvador and S\u00e3o Paulo. We compared the frequency of NCD and use of concomitant treatments in HIV patients, &gt;50 years, in three Brazilian referral centers (S\u00e3o Paulo and Salvador). Data on sociodemographic characteristics, HIV therapy, CD4 count and viral load measurements, and frequency of NCD at baseline and last medical visit were recorded. We evaluated 451 patients, 128 in Salvador and 323 in S\u00e3o Paulo. Mean age was 57.9\u2009\u00b1\u20096.9 years. Mean baseline CD4 count was 199\u2009\u00b1\u2009169. At baseline, dyslipidemia (4.0%) was the most frequent comorbidity, but at last visit we detected a high frequency of diabetes (14.9%), dyslipidemia (26.7%), osteoporosis (6.7%), stroke (4.4%), and malignancies (3.1%). Use of concomitant drugs for treatment of NCD increased significantly between first and last visit, especially antihypertensive, lipids lowering, and diabetes drugs. Aging in HIV patients in Brazil is characterized by an increasing incidence of NCD and polypharmacy.<\/jats:p>","DOI":"10.1089\/aid.2019.0069","type":"journal-article","created":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T06:47:12Z","timestamp":1566888432000},"page":"1103-1105","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Short Communication: Getting Older with HIV: Increasing Frequency of Comorbidities and Polypharmacy in Brazilian HIV Patients"],"prefix":"10.1177","volume":"35","author":[{"given":"Carlos","family":"Brites","sequence":"first","affiliation":[{"name":"LAPI-Laborat\u00f3rio de Pesquisa em Infectologia, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta Schiavon","family":"Nogueira","sequence":"additional","affiliation":[{"name":"CRT-Centro de Refer\u00eancia e Treinamento em DST-AIDS, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisele C.","family":"Gosuen","sequence":"additional","affiliation":[{"name":"Hospital S\u00e3o Paulo, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica M.C.","family":"Kalmar","sequence":"additional","affiliation":[{"name":"Hospital S\u00e3o Paulo, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana T.S.","family":"Leme","sequence":"additional","affiliation":[{"name":"Hospital S\u00e3o Paulo, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafaela T.","family":"Martins","sequence":"additional","affiliation":[{"name":"LAPI-Laborat\u00f3rio de Pesquisa em Infectologia, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiago","family":"Oyama","sequence":"additional","affiliation":[{"name":"Hospital S\u00e3o Paulo, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda A.","family":"Bastos","sequence":"additional","affiliation":[{"name":"LAPI-Laborat\u00f3rio de Pesquisa em Infectologia, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,11,13]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1590\/1809-98232016019.150140"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-11-251"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00056-0"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.25233"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/17512433.2017.1377610"},{"key":"e_1_3_3_7_2","unstructured":"Brazilian human development map. Available at www.atlasbrasil.org.br\/2013\/pt\/consulta\/ accessed February20 2018."},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.7.684"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/520652"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001374"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2018.02.009"}],"container-title":["AIDS Research and Human Retroviruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/aid.2019.0069","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2019.0069","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2019.0069","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:13:56Z","timestamp":1777367636000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/aid.2019.0069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":10,"journal-issue":{"issue":"11-12","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1089\/aid.2019.0069"],"URL":"https:\/\/doi.org\/10.1089\/aid.2019.0069","relation":{},"ISSN":["0889-2229","1931-8405"],"issn-type":[{"value":"0889-2229","type":"print"},{"value":"1931-8405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11]]}}}